HOME Research Insight Charles River Laboratories International, Inc. And the Jackson Laboratory To Dominate the Global Mice Model Market



Charles River Laboratories International, Inc. And the Jackson Laboratory To Dominate the Global Mice Model Market


Charles River Laboratories International, Inc. (U.S.), The Jackson Laboratory (U.S.), Taconic Biosciences, Inc. (U.S.), and Envigo (U.K.) are the top players in this market. These players jointly accounted for a share of 70% to 75% of the total mice model market in 2015.

Charles River Laboratories International, Inc. built upon its core competency of in vivo biology through its diverse products and services portfolio. It offers products, services, and solutions that focus specifically on early-stage drug discovery and preclinical development. The mice models offered by the company include inbred, outbred, hybrid, immunodeficient, congenic, and genetically engineered mice. The company also offers mice modeling services such as surgical service for rodents, genetic testing services, colony management services, and health monitoring services. The strong portfolio enables the company to increase collaboration with clients-from early lead generation to candidate selection. The firm acquired six companies in the last three years to improve its production and distribution capabilities as well as to strengthen its products and services portfolio. For instance, in September 2016, Charles River Laboratories International, Inc. acquired Agilux Laboratories, Inc. (U.S.), a provider of bioanalytical services, drug metabolism & pharmacokinetic services, and pharmacology services.

The Jackson Laboratory is an independent, non-profit organization and has a portfolio of over 2,500 targeted and 1,200 transgenic mutant mouse lines, and every year, over 600 hundred lines are added to this repository. In 2014, the company distributed 2.5 million JAX mice to approximately 20,000 investigators (or laboratories) in more than 900 institutions in 56 countries. The company also provides mice model services, including breeding, rederivation, cryopreservation, in vivo pharmacology services, and surgical & preconditioning services. The company receives a large number of grants that support the development of its mice model business. From 2013 to 2016, the company received nearly 30 grants/funds from leading health organizations, academic institutes, and government bodies such as National Institutes of Health (NIH) (U.S.), Howard Hughes Medical Institute (HHMI) (U.S.), Jane’s Trust (U.S.), Government of South Korea, Cogswell Rossi Foundation (U.S.), Maine Cancer Foundation (U.S.), Chordoma Foundation (U.S.), and National Human Genome Research Institute (U.S.). These grants helped the company develop new models, conduct specific studies on the models, compile genome-scale data sets for mice and humans, and examine various patterns of gene expression in mice that enable a better understanding of the genetic programs responsible for normal development and disease.

Taconic Biosciences, Inc. provides genetically modified rat and mice models and supporting services such as custom model generation, imaging studies, and surgical services. The company focused on developing unique models and established an “Emerging Models Program.” This program is a collaborative effort between Principal Investigators (PI) and Taconic to improve and develop new and developing transgenic rodent models. The program is currently working on light-producing transgenic animals (LPTA). Taconic also provides a unique tADMET portfolio of mice models that enabled the company to bridge the gap between the requirement and availability of human hepatocytes. The company is increasing its presence in untapped markets across Asia. For instance, in May 2016, Taconic Biosciences entered into a partnership with Life Technologies (India) Pvt. Ltd. to provide Taconic’s mice models and services to researchers in India and the Middle East.

Other players operating in this market adopted the strategy of collaborations/agreements/joint ventures/partnerships/alliances, expansions, product launches, acquisitions, and licensing to expand across different geographical regions and establish a strong foothold in the market.

Related Reports:

Mice Model Market by Type (Inbred, Knockout, Hybrid), Technology (CRISPR, Microinjection), Application (Oncology, Diabetes), Service (Breeding, Quarantine, Genetic testing) & Care Products (Bedding, Feed) - Analysis & Global Forecast to 2021

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