Protein A Resin Market

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Protein A Resin Market by Product (Agarose-based, Glass/Silica-based, Organic polymer-based), Type (Recombinant Protein A, Natural Protein A), Application (Antibody Purification, Immunoprecipitation), End User & Region - Global Forecast to 2028

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Report Code: AST 7818 Apr, 2023, by marketsandmarkets.com

Updated on : May 17, 2023

The global protein A resin market in terms of revenue was estimated to be worth $1.2 billion in 2022 and is poised to reach $2.1 billion by 2028, growing at a CAGR of 9.8% from 2022 to 2028 The new research study consists of an industry trend analysis of the market. The new research study consists of industry trends, pricing analysis, patent analysis, conference and webinar materials, key stakeholders, and buying behaviour in the market. Growth of the market is attributed to the increased R&D investments in pharmaceutical industries, the growing demand for protein engineered products used in the development of vaccines and therapeutics.

Global protein A resin market Trends

Protein A Resin Market

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Protein A Resin Market

Protein A resin Market Dynamics

Driver: Increasing demand for therapeutic antibodies

Chromatography is an essential step in the purification of monoclonal antibodies (mAbs). Over the past decade, there has been a tremendous increase in the demand for monoclonal antibodies in oncology and several other therapeutic areas, including neurological, autoimmune, and inflammatory disorders. As a result, almost all major pharmaceutical companies are focusing on the R&D of therapeutic antibodies.

In the purification of monoclonal antibodies, anionic impurities, such as nucleic acids and endotoxins, are removed through chromatography. In drug discovery applications, this process consumes a large number of resins, as the usage is not limited to purification but also includes the study of the ionic interaction of molecules. Impurities such as albumin and transferrin are removed by size-exclusion chromatography (SEC). High levels of purification can be achieved through the use of protein A affinity resins. This is because antibodies selectively bind protein A ligands with the resins. This is expected to drive the demand for protein A resins during the forecast period. In June 2020, UK’s Medicines and Healthcare Products Regulatory Agency planned for new regulations to come into force in 2023. Products that already have conformity markings, either UKCA or CE, will be able to remain in the market after the regulations come into force.

Restraint: High cost of resins

Protein A resins cost around 5–10 times more than other types of resins. Though there are no alternative techniques that can achieve purification levels as high as protein A resins, their high cost makes end users look for alternatives. Some of the techniques that provide acceptable levels of purification include both chromatography and non-chromatography methods. mAb crystallization and precipitation by polyethylene glycol (PEG) precipitation are being explored as alternatives for protein A chromatography.

The impact of this restraining factor is more evident in emerging markets such as the Asia Pacific and Latin America. However, with the entry of new market players, the cost of protein A resins is expected to come down significantly. The increasing pressure on major market players is expected to result in price reduction, as small market entrants are offering resins at far lower prices while simultaneously offering comparable product quality.

Opportunity: Increasing number of CMOs and CROs

An increasing number of CMOs and CROs are offering their services to pharmaceutical companies across the globe. This is expected to offer potential growth opportunities to protein A resin manufacturers during the forecast period.

Pharmaceutical companies are increasingly relying on contract manufacturers in various areas of research to fulfill a number of basic needs, such as specialized competencies and cost reduction. The pharmaceutical contract manufacturing industry has experienced robust growth in recent years, and this trend is expected to continue in the coming years. The increasing pressure from several governments to reduce healthcare costs and declining R&D productivity have compelled core pharmaceutical producers to rely on contract manufacturing. Moreover, the rising demand for generic drugs in China and India is a key driver for CMO sales.

In the biologics sector, the biosimilars market is expected to witness the highest growth. The patent expiry of blockbuster biologics is expected to encourage a number of companies to invest in biosimilars during the forecast period. Chromatography is one of the key bioseparation techniques used in the manufacturing of biosimilar antibodies. The rising demand for biosimilars is thus estimated to increase the use of chromatography resins during the forecast period.

The currently available biosimilars are used to treat cancer, rheumatoid arthritis, infectious diseases, psoriasis, anemia, kidney failure, Type I and Type II diabetes, post-menopausal osteoporosis, and hormonal disorders. The key targeted therapeutic areas for which various biosimilars are in the pipeline include oncology, autoimmune disorders, diabetes, and hepatitis. Besides these, biosimilars can be developed for other chronic disorders, such as meningitis, breast cancer, adult T-cell leukemia, obesity, hypertension, and hepatitis E.

Most of the early biologic drugs lost their patent protection in the first half of the 20th century, while many of the current best-selling drugs will lose their patent protection in the coming years. This is creating new opportunities for biosimilar drugs. For instance, in 2020, the patent of Vyrologix (Leronlimab), prescribed in the treatment of cancer, COVID-19, HIV, and cancer, expired in the US. This is expected to create significant opportunities for lower-priced Vyrologix biosimilars in the US and Europe.

Challenge: Issues associated with scaling up production of protein A resins

The production of protein A resins is a complex process that involves many steps, including fermentation, extraction, purification, and packaging. Scaling up the production process to meet the growing demand requires careful planning and management to ensure consistency and quality throughout the production process.

Scaling up the production process can result in variability in the quality and consistency of the resin. Factors such as changes in the source material, equipment, and personnel can all contribute to this variability. Maintaining consistency in the manufacturing process is essential to ensure the quality of the final product.

By product, the agarose-based protein A resin segment of global protein A resin market, accounted for the largest share during the forecast period.

Based on product, the market is segmented into agarose-based protein A resin, glass/silica based protein a resin and organic polymer based protein A resin. The agarose based protein A resin segment accounts for the largest share of the market. Agarose-based protein A resins exhibit enhanced durability, greater mechanical robustness, and a superior capacity to incorporate metal dopant absorption at pH levels that are appropriate.

By type, the recombinant protein A resin segment of protein A resin market, accounted for the largest share during the forecast period.

Based on type, the market is segmented into recombinant and natural protein A resin. The recombinant protein A resin segment accounts for the largest share of the market. Due to its advanced technological improvements in the drug discovery process, there is a rising need for recombinant protein resins in the pharmaceutical industry. This is because they offer a more targeted binding capacity, which is expected to propel the growth of this segment during the forecast period.

By application type, the antibody purification segment of protein A resin market is expected to witness a significant growth during the forecast period.

Based on application, the market is segmented into Based on application, the protein A resin is segmented into antibody purification, immunoprecipitation. The antibody purification segment is expected to witness a significant growth during the forecast period. The biopharmaceutical and biotechnology industries have facilitated the advancement of immunoprecipitation applications in the R&D sector, leading to its significant growth and dominance in the industry in the upcoming years.

By End User, pharmaceutical & biopharmaceutical companies’ segment of protein A resin market to grow at the fastest rate during the forecast period.

Based on end user, the global market is segmented into pharmaceutical & biopharmaceutical companies, academic and research institutes, other end users. The pharmaceutical and biopharmaceutical companies have facilitated the advancement of immunoprecipitation applications in the R&D sector, leading to its significant growth and dominance in the industry in the upcoming years. Also, the anticipated revenue growth of this segment during the forecast period is attributed to the rapid expansion of the biopharmaceutical industry worldwide and the technological advancements in the pharmaceutical and biotechnology sectors.

Protein A Resin Market by Region

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North America is expected to be the largest region of the global protein A resin market during the forecast period.

North America, comprising the US and Canada, held the largest share of the global market. This region is witnessing a surge in demand for protein-based therapeutics to combat infectious diseases, which is further amplified by the growing number of FDA-approved pharmaceutical and biotechnology companies in this region.

As of 2021, prominent players in the market are Danaher Corporation (US), Merck KGAa (Germany), Repligen Corporation (US), Thermo Fisher Scientific (US), Agilent Technologies (US), GenScript (China), PerkinElmer Inc. (US), Bio-Rad Laboratories, Inc. (US), Orochem Technologies Inc. (US), Kaneka Corporation (Japan), Abcam Plc. (UK), Agarose Bead Technologies (US), and Avantor, Inc. (US), among others.

Protein A Resin Market Report Scope:

Report Metric	Details
Market Revenue in 2022	$1.2 billion
Projected Revenue by 2028	$2.1 billion
Revenue Rate	poised to grow at a CAGR of 9.8%
Growth Driver	Increasing demand for therapeutic antibodies
Growth Opportunity	Increasing number of CMOs and CROs

This report has segmented the global protein A resin market to forecast revenue and analyze trends in each of the following submarkets:

By product

Agarose based protein A resin
Glass/Silica based protein A resin
Organic polymer based protein A resin

By Type

Recombinant protein A resin
Natural protein A resin

By Application

Antibody Purification
Immunoprecipitation

By end user

Pharmaceutical and biopharmaceutical companies
Academic Research institutes
Other end users

By Region

North America
- US
- Canada
Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
Asia Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest of Asia Pacific
Rest of the World

Recent Developments

In September 2022, As part of its charitable efforts through the Agilent Foundation, Agilent Technologies partnered with Delaware State University (DSU) to boost the number of minority students who choose STEM careers.
In October 2021, Tosoh Biosciences LLC completed the acquisition of Semba Biosciences, a privately held leading innovator in the field of multi-column chromatography (MCC) instrumentation and technology for the downstream purification of biologics.
In September 2021, Repligen and Navigo completed their co-development of a novel affinity ligand that addresses aggregation issues associated with pH-sensitive antibodies and Fc-fusion proteins. This ligand, NGL-Impact HipH, is produced and supplied to Purolite for use in a platform usage resin product.
In May 2021, The Life Sciences business of GE Healthcare was acquired by Danaher Corporation and rebranded as Cytiva.

Frequently Asked Questions (FAQ):

What is the projected market revenue value of the protein A resin market?

The protein A resin market boasts a total revenue value of $2.1 billion by 2028.

What is the estimated growth rate (CAGR) of the protein A resin market?

The global protein A resin market has an estimated compound annual growth rate (CAGR) of 9.8% and a revenue size in the region of $1.2 billion in 2022.

To speak to our analyst for a discussion on the above findings, click Speak to Analyst

TABLE OF CONTENTS

1 INTRODUCTION (Page No. - 18)

1.1 STUDY OBJECTIVES

1.2 MARKET DEFINITION

1.3 INCLUSIONS AND EXCLUSIONS

TABLE 1 PROTEIN A RESIN MARKET: INCLUSIONS AND EXCLUSIONS

1.4 MARKETS COVERED

FIGURE 1 MARKET SEGMENTATION

1.4.1 GEOGRAPHIC SEGMENTATION

1.5 YEARS CONSIDERED

1.6 CURRENCY CONSIDERED

1.7 LIMITATIONS

1.8 STAKEHOLDERS

1.9 SUMMARY OF CHANGES

2 RESEARCH METHODOLOGY (Page No. - 23)

2.1 RESEARCH DATA

2.2 RECESSION IMPACT

FIGURE 2 RESEARCH DESIGN

2.2.1 SECONDARY RESEARCH

2.2.2 PRIMARY RESEARCH

2.2.2.1 Primary sources

2.2.2.2 Key industry insights

2.2.2.3 Breakdown of primaries

FIGURE 3 BREAKDOWN OF PRIMARY INTERVIEWS: SUPPLY-SIDE AND DEMAND-SIDE PARTICIPANTS

FIGURE 4 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION

2.3 RESEARCH ASSUMPTION

FIGURE 5 RESEARCH METHODOLOGY: HYPOTHESIS BUILDING

2.3.1 BOTTOM-UP APPROACH

2.3.1.1 Approach 1: Company revenue estimation approach

FIGURE 6 MARKET SIZE ESTIMATION: VENDOR REVENUE MAPPING APPROACH

FIGURE 7 ANALYSIS OF VENDOR REVENUE MAPPING

2.3.1.2 Approach 2: Customer-based market estimation

FIGURE 8 MARKET SIZE ESTIMATION: BOTTOM-UP APPROACH

2.3.1.3 CAGR projection

FIGURE 9 CAGR PROJECTION: SUPPLY-SIDE ANALYSIS

2.4 DATA VALIDATION APPROACH

FIGURE 10 DATA TRIANGULATION METHODOLOGY

2.5 MARKET SHARE ASSESSMENT

2.6 STUDY ASSUMPTIONS

2.7 RISK ASSESSMENT

2.7.1 MARKET: RISK ASSESSMENT

2.8 GROWTH RATE ASSUMPTIONS

3 EXECUTIVE SUMMARY (Page No. - 36)

FIGURE 11 PROTEIN A RESIN MARKET, BY PRODUCT, 2022 VS. 2028 (USD MILLION)

FIGURE 12 MARKET, BY TYPE, 2022 VS. 2028 (USD MILLION)

FIGURE 13 MARKET, BY APPLICATION, 2022 VS. 2028 (USD MILLION)

FIGURE 14 MARKET, BY END USER, 2022 VS. 2028 (USD MILLION)

FIGURE 15 GEOGRAPHIC SNAPSHOT: MARKET

4 PREMIUM INSIGHTS (Page No. - 40)

4.1 PROTEIN A RESIN MARKET OVERVIEW

FIGURE 16 INCREASING DEMAND FOR PRE-PACKED DISPOSABLE COLUMNS TO DRIVE MARKET GROWTH

4.2 NORTH AMERICA: MARKET, BY PRODUCT, 2022 VS. 2028 (USD MILLION)

FIGURE 17 AGAROSE-BASED PROTEIN A SEGMENT TO DOMINATE NORTH AMERICAN MARKET DURING FORECAST PERIOD

4.3 ASIA PACIFIC: MARKET, BY END USER, 2022 VS. 2028 (USD MILLION)

FIGURE 18 PHARMACEUTICAL AND BIOPHARMACEUTICAL COMPANIES SEGMENT TO CONTINUE TO DOMINATE ASIA PACIFIC MARKET DURING FORECAST PERIOD

4.4 GEOGRAPHIC SNAPSHOT OF MARKET

FIGURE 19 CHINA TO WITNESS HIGHEST GROWTH DURING FORECAST PERIOD

5 MARKET OVERVIEW (Page No. - 43)

5.1 INTRODUCTION

5.2 MARKET DYNAMICS

FIGURE 20 PROTEIN A RESIN MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES

5.2.1 DRIVERS

5.2.1.1 Growing demand for disposable pre-packed columns

TABLE 2 ADVANTAGES OF PRE-PACKED COLUMNS

5.2.1.2 Increasing demand for therapeutic antibodies

5.2.1.3 Increasing pharmaceutical R&D spending

5.2.1.4 Stringent regulatory control in healthcare industry

5.2.2 RESTRAINTS

5.2.2.1 High cost of resins

5.2.2.2 Dearth of skilled professionals

5.2.3 OPPORTUNITIES

5.2.3.1 Increasing number of CMOs and CROs

5.2.4 CHALLENGES

5.2.4.1 Regulatory restrictions

5.2.4.2 Issues associated with scaling up production of protein A resins

5.3 REGULATIONS

5.3.1 NORTH AMERICA

5.3.1.1 US

5.3.1.2 Canada

5.3.2 EUROPE

5.3.3 ASIA PACIFIC

5.3.4 LATIN AMERICA

5.3.5 MIDDLE EAST & AFRICA

5.4 PRICING ANALYSIS: MARKET

5.5 PORTER’S FIVE FORCES ANALYSIS

TABLE 3 MARKET: PORTER’S FIVE FORCES ANALYSIS

5.5.1 THREAT OF SUBSTITUTES

5.5.2 BARGAINING POWER OF SUPPLIERS

5.5.3 BARGAINING POWER OF BUYERS

5.5.4 THREAT OF NEW ENTRANTS

5.5.5 INTENSITY OF COMPETITIVE RIVALRY

6 PROTEIN A RESIN MARKET, BY PRODUCT (Page No. - 53)

6.1 INTRODUCTION

TABLE 4 MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

6.2 AGAROSE-BASED PROTEIN A

6.2.1 AGAROSE-BASED PROTEIN A SEGMENT TO DOMINATE MARKET

TABLE 5 AGAROSE-BASED PROTEIN A MARKET, BY REGION, 2020–2028 (USD MILLION)

TABLE 6 NORTH AMERICA: AGAROSE-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 7 EUROPE: AGAROSE-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 8 ASIA PACIFIC: AGAROSE-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

6.3 GLASS/SILICA-BASED PROTEIN A

6.3.1 LOW PH TOLERANCE OF SILICA-BASED RESINS TO LIMIT THEIR MARKET GROWTH

TABLE 9 GLASS/SILICA-BASED PROTEIN A MARKET, BY REGION, 2020–2028 (USD MILLION)

TABLE 10 NORTH AMERICA: GLASS/SILICA-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 11 EUROPE: GLASS/SILICA-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 12 ASIA PACIFIC: GLASS/SILICA-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

6.4 ORGANIC POLYMER-BASED PROTEIN A

6.4.1 INCREASING POPULARITY OF ORGANIC POLYMERS TO DRIVE MARKET GROWTH

TABLE 13 ORGANIC POLYMER-BASED PROTEIN A MARKET, BY REGION, 2020–2028 (USD MILLION)

TABLE 14 NORTH AMERICA: ORGANIC POLYMER-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 15 EUROPE: ORGANIC POLYMER-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 16 ASIA PACIFIC: ORGANIC POLYMER-BASED PROTEIN A MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

7 PROTEIN A RESIN MARKET, BY TYPE (Page No. - 61)

7.1 INTRODUCTION

TABLE 17 MARKET, BY TYPE, 2020–2028 (USD MILLION)

7.2 RECOMBINANT PROTEIN A

7.2.1 COST-EFFICIENCY OF RECOMBINANT PROTEINS TO DRIVE MARKET GROWTH

TABLE 18 RECOMBINANT PROTEIN A MARKET, BY REGION, 2020–2028 (USD MILLION)

7.3 NATURAL PROTEIN A

7.3.1 ADVANTAGES OF RECOMBINANT PROTEIN A HAVE RESTRICTED MARKET POTENTIAL OF NATURAL PROTEIN A

TABLE 19 NATURAL PROTEIN A MARKET, BY REGION, 2020–2028 (USD MILLION)

8 PROTEIN A RESIN MARKET, BY APPLICATION (Page No. - 64)

8.1 INTRODUCTION

TABLE 20 MARKET, BY APPLICATION, 2020–2028 (USD MILLION)

8.2 ANTIBODY PURIFICATION

8.2.1 ANTIBODY PURIFICATION SEGMENT TO DOMINATE MARKET DURING FORECAST PERIOD

TABLE 21 MARKET FOR ANTIBODY PURIFICATION, BY REGION, 2020–2028 (USD MILLION)

8.3 IMMUNOPRECIPITATION

8.3.1 IMMUNOPRECIPITATION SEGMENT TO GROW AT LOWER CAGR DURING FORECAST PERIOD

TABLE 22 MARKET FOR IMMUNOPRECIPITATION, BY REGION, 2020–2028 (USD MILLION)

9 PROTEIN A RESIN MARKET, BY END USER (Page No. - 67)

9.1 INTRODUCTION

TABLE 23 MARKET, BY END USER, 2020–2028 (USD MILLION)

9.2 PHARMACEUTICAL AND BIOPHARMACEUTICAL COMPANIES

9.2.1 PROTEIN A RESINS EXTENSIVELY USED TO PRODUCE BIOLOGICAL DRUGS

FIGURE 21 SPENDING ON PHARMACEUTICAL RESEARCH AND DEVELOPMENT, 2020–2028 (USD BILLION)

TABLE 24 MARKET FOR PHARMACEUTICAL AND BIOPHARMACEUTICAL COMPANIES, BY REGION, 2020–2028 (USD MILLION)

9.3 ACADEMIC RESEARCH INSTITUTES

9.3.1 INCREASING R&D IN DRUG DISCOVERY TO DRIVE USE OF PROTEIN A RESINS

TABLE 25 MARKET FOR ACADEMIC RESEARCH INSTITUTES, BY REGION, 2020–2028 (USD MILLION)

9.4 OTHER END USERS

TABLE 26 MARKET FOR OTHER END USERS, BY REGION, 2020–2028 (USD MILLION)

10 PROTEIN A RESIN MARKET, BY REGION (Page No. - 72)

10.1 INTRODUCTION

TABLE 27 MARKET, BY REGION, 2020–2028 (USD MILLION)

10.2 NORTH AMERICA

FIGURE 22 NORTH AMERICA: PROTEIN A RESIN MARKET SNAPSHOT

TABLE 28 NORTH AMERICA: MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 29 NORTH AMERICA: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

TABLE 30 NORTH AMERICA: MARKET, BY TYPE, 2020–2028 (USD MILLION)

TABLE 31 NORTH AMERICA: MARKET, BY APPLICATION, 2020–2028 (USD MILLION)

TABLE 32 NORTH AMERICA: MARKET, BY END USER, 2020–2028 (USD MILLION)

10.2.1 US

10.2.1.1 Increasing R&D investments in pharmaceutical industry to propel market growth

TABLE 33 US: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.2.2 CANADA

10.2.2.1 Government initiatives focused on boosting pharmaceutical industry to drive market growth

TABLE 34 CANADA: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.3 EUROPE

TABLE 35 EUROPE: PROTEIN A RESIN MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 36 EUROPE: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

TABLE 37 EUROPE: MARKET, BY TYPE, 2020–2028 (USD MILLION)

TABLE 38 EUROPE: MARKET, BY APPLICATION, 2020–2028 (USD MILLION)

TABLE 39 EUROPE: MARKET, BY END USER, 2020–2028 (USD MILLION)

10.3.1 GERMANY

10.3.1.1 Flourishing biotechnology industry to drive market growth

TABLE 40 GERMANY: PROTEIN A RESIN MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.3.2 UK

10.3.2.1 Favorable R&D scenario to support market growth

TABLE 41 UK: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.3.3 FRANCE

10.3.3.1 Favorable healthcare scenario to boost market growth

TABLE 42 FRANCE: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.3.4 ITALY

10.3.4.1 Well-established pharmaceutical industry to spur demand for protein A resins

TABLE 43 ITALY: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.3.5 SPAIN

10.3.5.1 Presence of large number of biotech R&D service providers to support market growth

TABLE 44 SPAIN: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.3.6 REST OF EUROPE

TABLE 45 REST OF EUROPE: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.4 ASIA PACIFIC

FIGURE 23 ASIA PACIFIC: PROTEIN A RESIN MARKET SNAPSHOT

TABLE 46 ASIA PACIFIC: MARKET, BY COUNTRY, 2020–2028 (USD MILLION)

TABLE 47 ASIA PACIFIC: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

TABLE 48 ASIA PACIFIC: MARKET, BY TYPE, 2020–2028 (USD MILLION)

TABLE 49 ASIA PACIFIC: MARKET, BY APPLICATION, 2020–2028 (USD MILLION)

TABLE 50 ASIA PACIFIC: MARKET, BY END USER, 2020–2028 (USD MILLION)

10.4.1 JAPAN

10.4.1.1 Increasing demand for generic drugs and monoclonal antibody biosimilars to drive resin consumption

TABLE 51 JAPAN: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.4.2 CHINA

10.4.2.1 Increasing pharmaceutical R&D spending to drive market growth

TABLE 52 CHINA: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.4.3 INDIA

10.4.3.1 Growth of pharma and biotech industries to drive demand for protein A resins

TABLE 53 INDIA: PROTEIN A RESIN MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.4.4 AUSTRALIA

10.4.4.1 Increasing demand for protein-based therapeutics for treatment of infectious diseases to drive growth

TABLE 54 AUSTRALIA: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.4.5 SOUTH KOREA

10.4.5.1 Developments in biopharmaceutical sector to drive market growth

TABLE 55 SOUTH KOREA: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.4.6 REST OF ASIA PACIFIC

TABLE 56 REST OF ASIA PACIFIC: MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

10.5 REST OF THE WORLD

TABLE 57 ROW: PROTEIN A RESIN MARKET, BY PRODUCT, 2020–2028 (USD MILLION)

TABLE 58 ROW: MARKET, BY TYPE, 2020–2028 (USD MILLION)

TABLE 59 ROW: MARKET, BY APPLICATION, 2020–2028 (USD MILLION)

TABLE 60 ROW: MARKET, BY END USER, 2020–2028 (USD MILLION)

11 COMPETITIVE LANDSCAPE (Page No. - 94)

11.1 OVERVIEW

11.2 MARKET SHARE ANALYSIS

FIGURE 24 PROTEIN A RESIN MARKET SHARE ANALYSIS (2021)

11.3 COMPETITIVE LEADERSHIP MAPPING

11.3.1 STARS

11.3.2 EMERGING LEADERS

11.3.3 PERVASIVE PLAYERS

11.3.4 PARTICIPANTS

FIGURE 25 MARKET: COMPETITIVE LEADERSHIP MAPPING (2022)

11.4 COMPETITIVE SCENARIO

11.4.1 PRODUCT LAUNCHES

TABLE 61 MARKET: PRODUCT LAUNCHES, JANUARY 2020 TO FEBRUARY 2023

11.4.2 DEALS

TABLE 62 MARKET: DEALS, JANUARY 2020 TO FEBRUARY 2023

11.4.3 OTHER DEVELOPMENTS

TABLE 63 MARKET: OTHER DEVELOPMENTS, JANUARY 2020 TO FEBRUARY 2023

12 COMPANY PROFILES (Page No. - 99)

12.1 KEY PLAYERS

(Business Overview, Products/Services/Solutions Offered, MnM View, Key Strengths and Right to Win, Strategic Choices Made, Weaknesses and Competitive Threats, Recent Developments)*

12.1.1 DANAHER CORPORATION

TABLE 64 DANAHER CORPORATION: COMPANY OVERVIEW

FIGURE 26 DANAHER CORPORATION: COMPANY SNAPSHOT (2021)

12.1.2 THERMO FISHER SCIENTIFIC

TABLE 65 THERMO FISHER SCIENTIFIC: COMPANY OVERVIEW

FIGURE 27 THERMO FISHER SCIENTIFIC: COMPANY SNAPSHOT (2022)

12.1.3 MERCK KGAA

TABLE 66 MERCK KGAA: COMPANY OVERVIEW

FIGURE 28 MERCK KGAA: COMPANY SNAPSHOT (2022)

12.1.4 REPLIGEN CORPORATION

TABLE 67 REPLIGEN CORPORATION: COMPANY OVERVIEW

FIGURE 29 REPLIGEN CORPORATION: COMPANY SNAPSHOT (2022)

12.1.5 TOSOH BIOSCIENCE LLC

TABLE 68 TOSOH BIOSCIENCE LLC: COMPANY OVERVIEW

FIGURE 30 TOSOH BIOSCIENCE LLC: COMPANY SNAPSHOT (2021)

12.1.6 AGILENT TECHNOLOGIES, INC.

TABLE 69 AGILENT TECHNOLOGIES, INC.: COMPANY OVERVIEW

FIGURE 31 AGILENT TECHNOLOGIES INC.: COMPANY SNAPSHOT (2022)

12.1.7 PUROLITE

TABLE 70 PUROLITE: COMPANY OVERVIEW

12.1.8 PERKINELMER INC.

TABLE 71 PERKINELMER INC.: COMPANY OVERVIEW

FIGURE 32 PERKINELMER INC.: COMPANY SNAPSHOT (2022)

12.1.9 NOVASEP HOLDING SAS

TABLE 72 NOVASEP HOLDING SAS: COMPANY OVERVIEW

12.1.10 GENSCRIPT

TABLE 73 GENSCRIPT: COMPANY OVERVIEW

FIGURE 33 GENSCRIPT: COMPANY SNAPSHOT (2021)

12.1.11 BIO-RAD LABORATORIES, INC.

TABLE 74 BIO-RAD LABORATORIES, INC.: COMPANY OVERVIEW

FIGURE 34 BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT (2022)

12.1.12 KANEKA CORPORATION

TABLE 75 KANEKA CORPORATION: COMPANY OVERVIEW

FIGURE 35 KANEKA CORPORATION: COMPANY SNAPSHOT (2021)

12.1.13 OROCHEM TECHNOLOGIES INC.

TABLE 76 OROCHEM TECHNOLOGIES INC.: COMPANY OVERVIEW

12.1.14 ABCAM PLC

TABLE 77 ABCAM PLC.: COMPANY OVERVIEW

12.1.15 AGAROSE BEAD TECHNOLOGIES

TABLE 78 AGAROSE BEAD TECHNOLOGIES: COMPANY OVERVIEW

*Business Overview, Products/Services/Solutions Offered, MnM View, Key Strengths and Right to Win, Strategic Choices Made, Weaknesses and Competitive Threats, Recent Developments might not be captured in case of unlisted companies.

12.2 OTHER COMPANIES

12.2.1 AVANTOR, INC.

12.2.2 JSR LIFESCIENCES, LLC

12.2.3 BIO-WORKS

12.2.4 TAKARA BIO INC.

12.2.5 GENERON

12.2.6 GENO TECHNOLOGY INC.

12.2.7 JNC CORPORATION

12.2.8 PROMEGA CORPORATION

12.2.9 SUZHOU NANOMICRO TECHNOLOGY CO., LTD.

12.2.10 TRANSGEN BIOTECH CO., LTD.

13 APPENDIX (Page No. - 140)

13.1 DISCUSSION GUIDE

13.2 KNOWLEDGESTORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL

13.3 CUSTOMIZATION OPTIONS

13.4 RELATED REPORTS

13.5 AUTHOR DETAILS

This study involved the extensive use of both primary and secondary sources. The research process involved the study of various factors affecting the industry to identify the segmentation types, industry trends, key players, competitive landscape, key market dynamics, and key player strategies.

Secondary Research

The secondary research process involves the widespread use of secondary sources, directories, databases (such as Bloomberg Businessweek, Factiva, and D&B Hoovers), white papers, annual reports, company house documents, investor presentations, and SEC filings of companies. Secondary research was used to identify and collect information useful for the extensive, technical, market-oriented, and commercial study of the protein A resin market. It was also used to obtain important information about the key players and market classification & segmentation according to industry trends to the bottom-most level and key developments related to market and technology perspectives. A database of the key industry leaders was also prepared using secondary research.

Primary Research

In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include industry experts such as CEOs, vice presidents, marketing and sales directors, technology & innovation directors, and related key executives from various key companies and organizations in the protein A resin market. The primary sources from the demand side include medical OEMs, Analytical instrument OEMs, CDMOs, and service providers, among others. Primary research was conducted to validate the market segmentation, identify key players in the market, and gather insights on key industry trends & key market dynamics.

A breakdown of the primary respondents is provided below:

Protein A Resin Market Size, and Share

*Others include sales managers, marketing managers, business development managers, product managers, distributors, and suppliers.

Note: Companies are classified into tiers based on their total revenue. As of 2021, Tier 1 = >USD 2 billion, Tier 2 = USD 50 million to USD 2 billion, and Tier 3 = <USD 50 million.

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Company Name	Designation
Tosoh Bioscience LLC	Application Manager
Cytiva	Product Sales Specialist
Cytiva	Product Manager

Market Estimation Methodology

In this report, the global protein A resin market size was arrived at by using the revenue share analysis of leading players. For this purpose, key players in the market were identified, and their revenues from the protein A resin business were determined through various insights gathered during the primary and secondary research phases. Secondary research included the study of the annual and financial reports of the top market players. In contrast, primary research included extensive interviews with key opinion leaders, such as CEOs, directors, and key marketing executives.

To calculate the global market value, segmental revenues were calculated based on the revenue mapping of major solution/service providers. This process involved the following steps:

Generating a list of major global players operating in the protein A resin market
Mapping annual revenues generated by major global players from the protein A resin segment (or nearest reported business unit/product category)
Revenue mapping of key players to cover major share of the global market, as of 2021
Extrapolating the global value of the protein A resin industry

Protein A Resin Market Size, and Share

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Data Triangulation

After arriving at the overall market size from the market size estimation process explained above, the global protein A resin market was split into segments and subsegments. Data triangulation and market breakdown procedures were employed to complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments. The data was triangulated by studying various factors and trends from both the demand and supply sides. Additionally, the market was validated using both top-down and bottom-up approaches.

Objectives of the Study

To define, describe, and forecast the protein A resin market on the basis of product, type, application, end user, and region
To provide detailed information regarding the major factors influencing the growth potential of the global market (drivers, restraints, opportunities, challenges, and trends)
To analyze the micro markets with respect to individual growth trends, future prospects, and contributions to the global market
To analyze key growth opportunities in the global market for key stakeholders and provide details of the competitive landscape for market leaders
To forecast the size of market segments and/or subsegments with respect to five major regions, namely, North America (US and Canada), Europe (Germany, France, the UK, Italy, Spain, and the RoE), Asia Pacific (Japan, China, India, Australia, South Korea, and the RoAPAC), and rest of the world.
To profile the key players in the global market and comprehensively analyze their market shares and core competencies
To track and analyze the competitive developments undertaken in the global protein A resin market, such as product launches, agreements, expansions, and & acquisitions

Available Customizations

With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for the present global protein A resin market report:

Product Analysis

Product matrix, which gives a detailed comparison of the product portfolios of the top fifteen companies

Geographic Analysis

Further breakdown of the Rest of Europe market into Russia, Belgium, the Netherlands, Switzerland, Austria, Finland, Sweden, Poland, and Portugal among other
Further breakdown of the Rest of Asia Pacific market into Singapore, Taiwan, New Zealand, Philippines, Malaysia, and other APAC countries
Further breakdown of the Rest of the world market into Latin America, MEA, and Africa

Custom Market Research Services

We will customize the research for you, in case the report listed above does not meet with your exact requirements. Our custom research will comprehensively cover the business information you require to help you arrive at strategic and profitable business decisions.