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Top 10 Drug Discovery Technologies Market – Strategic Analysis and Global Forecasts (2010 to 2015)

By: marketsandmarkets.com
Publishing Date: November 2010
Report Code: BT 1028

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The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry as they are the key contributors in the swift introduction of blockbusters and innovative drugs, which is the most important aspect for the pharmaceutical companies. The applications of these technologies in the introduction of drugs for diverse diseases such as cancer, CVD, CNS disorders such as Parkinson’s and Alzheimer’s and other serious chronic diseases have created significant opportunities for the market growth in the future. The slow growth of the introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies.

The global top 10 drug discovery technologies market is expected to be around $ 30.8 billion in 2010 and estimated to reach $ 54 billion mark in 2015, growing at a CAGR of 11.9 % from 2010-2015. The market for high throughput screening accounts for the largest share with approximately 33% of the entire market for top 10 drug discovery technologies. This huge market share is mainly due to the increasing applications of cell based assays and robotics in the parallel screening of compounds.

Scope of the report

This research report includes following drug discovery technologies:

  • High throughput screening (robotics and automation, cell based assays, miniaturization, high content screening and ultra high throughput screening)
  • Bioanalytical instruments (mass spectrometry, NMR, micro plate readers and chemotherapy instruments)
  • Pharmacogenomics
  • Combinatorial chemistry
  • Genomics (functional and structural genomics)
  • Biochips (DNA microarrays, lab on a chip, proteomics microarrays)
  • Bioinformatics
  • Proteomics (2DGE, two hybrid systems, isotope encoding and activity based assays)
  • RNAi (siRNA, miRNA, ddRNAi, short hairpin RNAs)
  • Nanotechnology (Atomic force microscopy, nano mass spectroscopy, dip pen nanolithography and other nanotechnologies)

Each section will provide market data, market drivers, trends and opportunities, top-selling products, key players, and competitive outlook. This report will also provide market tables for covering the sub-segments and micro-markets. In addition, the report also provides more than 20 company profiles covering all the sub-segments.

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Pharmaceuticals, Medical Devices, Biotechnology, Semiconductor and Electronics, Energy and Power Supplies, Food and Beverages, Chemicals, Advanced Materials, Industrial Automation, and Telecom and IT. We also analyze retailers and super-retailers, technology providers, and research and development (R&D) companies.

Key questions answered

  • Which are the high-growth segments/cash cows and how is the market segmented in terms of applications and materials?
  • What are market estimates and forecasts; which markets are doing well and which are not?
  • Where are the gaps and opportunities; what is driving the market?
  • Which are the key playing fields? Which are the winning edge imperatives?
  • How is the competitive outlook; who are the main players in each of the segments; what are the key selling products; what are their strategic directives, operational strengths and product pipelines? Who is doing what?

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TABLE OF CONTENTS

EXECUTIVE SUMMARY  
 Objective 
 Market scenario 
 
1 INTRODUCTION 
   1.1 Key take-aways 
   1.2 Report description 
   1.3 Markets covered 
   1.4 Research methodology 
   1.5 Stakeholders 
 
2 SUMMARY 
 
3 MARKET OVERVIEW 
   3.1 Market segmentation 
   3.2 High throughput screening & bioanalytical instruments leading the market 
   3.3 Patent analysis 
 
4 DRIVING FACTOR ANALYSIS 
   4.1 Drivers 
         4.1.1 Contract research boosting technology adoption 
         4.1.2 Collaborations between academia & pharmaceutical industry 
         4.1.3 Increased necessity for ADME/toxicity technologies 
   4.2 Opportunities 
         4.2.1 Offshoring scenario for drug discovery 
 
5 HIGH THROUGHPUT SCREENING 
   5.1 Introduction 
   5.2 Market overview 
   5.3 Burning issues & winning imperatives 
         5.3.1 Increasing participation from academic research 
         5.3.2 High throughput screening set up: pharmaceutical vs academic 
   5.4 Ultra high throughput screening 
   5.5 Robotics & automation 
   5.6 Miniaturization 
   5.7 High content screening 
         5.7.1 Opportunities 
                5.7.1.1 GPCR drug discovery 
   5.8 Cell based assays 
 
6 BIOANALYTICAL INSTRUMENTS 
   6.1 Introduction 
   6.2 Burning issues & trends 
         6.2.1 Pharmaceutical industry a major end client 
         6.2.2 Agilent penetration in bioanalytical instruments market 
         6.2.3 Outsourcing scenario 
   6.3 Mass spectrometry 
         6.3.1 Upcoming technology - Maldi-QMS 
   6.4 Microplate readers 
   6.5 Nuclear magnetic resonance 
   6.6 Chemotherapy instruments 
 
7 Pharmacogenomics 
   7.1 Introduction 
   7.2 Pharmacogenomics applications in drug development 
   7.3 Burning issues 
         7.3.1 Commercial hurdles in drug development 
                7.3.1.1 Cost issues in clinical development 
                7.3.1.2 FDA approval 
                7.3.1.3 Ethical issues 
         7.3.2 Pharmacogenomics for drug reintroduction 
         7.3.3 Pharmacogenomics applications in existing drugs 
   7.4 Key trends in the pharmacogenomics technology market 
         7.4.1 Regulatory initiatives boosting adoption for pharmacogenomics technology 
         7.4.2 Rise in pharmacogenomics consortia boost technology based research 
         7.4.3 Increasing importance of databases 
   7.5 Future prospects for pharmacogenomics technology research 
   7.6 Pharmacogenomics products: pricing effects 
         7.6.1 Case study: high priced herceptin 
         7.6.2 Pharmacogenomics cost effectiveness 
   7.7 Pharmacogenomics technology: short & long term benefits 
         7.7.1 Improvement in patient safety 
         7.7.2 Increase in drug effectiveness 
         7.7.3 Selection of medication for chronic diseases 
         7.7.4 Better economic efficiency for the healthcare system 
         7.7.5 Improved patient access to drugs 
 
8 COMBINATORIAL CHEMISTRY 
   8.1 Introduction 
   8.2 Market drivers 
         8.2.1 Technological advances boost adoption of combinatorial chemistry 
         8.2.2 Process enhancement results in better compounds 
         8.2.3 Collaborative approach 
         8.2.4 Need for novel compounds acts as market opportunity 
   8.3 Stakeholders characteristics 
   8.4 Burning issues 
   8.5 Key trends and market boosters 
         8.5.1 Increased recognition of combinatorial chemistry technology 
         8.5.2 Faster drug discovery 
 
9 GENOMICS 
   9.1 Introduction 
   9.2 Winning imperatives 
         9.2.1 Reducing cost for whole genome sequencing 
   9.3 Functional genomics 
   9.4 Structural genomics 
 
10 BIOCHIPS 
   10.1 Introduction 
   10.2 Burning issues 
         10.2.1 Business trends 
         10.2.2 Patent disputes 
         10.2.3 Competition 
   10.3 Industry trends 
         10.3.1 Next generation technology: microfluidics with CD-ROM 
         10.3.2 Biochips in biomarker development 
         10.3.3 Outsourcing the biochip technology 
   10.4 DNA microarrays 
         10.4.1 Market drivers 
                10.4.1.1 Increased utilization in complex diseases 
                10.4.1.2 Sequence data proliferation 
                10.4.1.3 Easy-access programs 
   10.5 Lab on a chip 
         10.5.1. New technology & cost saving by lab on a chip boost the market 
   10.6 Proteomics microarrays 
         10.6.1 Burning issues and trends 
                10.6.1.1 Technical lags 
                10.6.1.2 Human protein microarray for multiple protein analysis 
 
11 BIOINFORMATICS 
   11.1 Introduction 
   11.2 Burning issues and trends 
         11.2.1 Outsourcing 
         11.2.2 Allocation of grants 
 
12 PROTEOMICS 
   12.1 Introduction 
   12.2 Industry trends 
         12.2.1 Funding for proteomics research 
         12.2.2 Proteomics in anti cancer drug discovery 
   12.3 Two dimensional gel electrphoresis- 2DGE 
   12.4 Two-hybrid systems 
 
13 RNAI 
   13.1 Technology overview 
   13.2 Winning imperatives 
         13.2.1 Core competency acquisition 
   13.3 Opportunity in RNAi drug discovery 
         13.3.1 RNAi based cholesterol drugs 
         13.3.2 Cancer drugs 
   13.4 SiRNA 
   13.5 MiRNAS 
   13.6 Other RNAi technologies 
 
14 NANOTECHNOLOGY 
   14.1 Introduction 
   14.2 Healthcare application areas for nanotechnology 
         14.2.1 Biomedical research 
         14.2.2 Therapeutics 
         14.2.3 Diagnostics 
   14.3 Burning issues and trends 
         14.3.1 Regulatory & health issues 
         14.3.2 Increase in funding 
   14.4 Atomic force microscopy (AFM) 
   14.5 Nano-mass spectroscopy 
   14.6 Dip-pen Nanolithography 
 
15 GEOGRAPHICAL ANALYSIS 
   15.1 Introduction 
   15.2 North America 
   15.3 Europe 
   15.4 Asia 
   15.5 ROW 
 
16 COMPETITIVE LANDSCAPE 
   16.1 Market share for drug discovery technologies 
   16.2 Agreements & collaborations 
   16.3 New product launch 
   16.4 End clients for top 10 drug discovery technologies 
 
17 COMPANY PROFILES 
   17.1 ABBOTT LABORATORIES INC.
 17.1.1 Overview
 17.1.2 Primary business
 17.1.3 Strategy
 17.1.4 Developments
   17.2 AFFYMETRIX INC.
 17.2.1 Overview
 17.2.2 Primary business
 17.2.3 Strategy
 17.2.4 Developments
   17.3 AGILENT TECHNOLOGIES INC.
 17.3.1 Overview
 17.3.2 Primary business
 17.3.3 Strategy
 17.3.4 Developments
   17.4 ALBANY MOLECULAR RESEARCH INC.
 17.4.1 Overview
 17.4.2 Primary business
 17.4.3 Strategy
 17.4.4 Developments
   17.5 ARQULE INC.
 17.5.1 Overview
 17.5.2 Primary business
 17.5.3 Strategy
 17.5.4 Developments
   17.6 ASTRAZENECA PLC.
 17.6.1 Overview
 17.6.2 Primary business
 17.6.3 Strategy
 17.6.4 Developments
   17.7 BIO-RAD LABORATORIES INC.
 17.7.1 Overview
 17.7.2 Primary business
 17.7.3 Strategy
 17.7.4 Developments
   17.8 CALIPER LIFE SCIENCES INC.
 17.8.1 Overview
 17.8.2 Primary business
 17.8.3 Strategy
 17.8.4 Developments
   17.9 CELERA CORP
 17.9.1 Overview
 17.9.2 Primary business
 17.9.3 Strategy
 17.9.4 Developments
  17.10 CHARLES RIVER LABORATORIES INTERNATIONAL INC.
 17.10.1 Overview
 17.10.2 Primary business
 17.10.3 Strategy
 17.10.4 Developments
  17.11 CHEMBRIDGE CORP
 17.11.1 Overview
 17.11.2 Primary business
 17.11.3 Strategy
 17.11.4 Developments
  17.12 EVOTEC AG
 17.12.1 Overview
 17.12.2 Primary business
 17.12.3 Strategy
 17.12.4 Developments
  17.13 F. HOFFMANN-LA ROCHE LTD.
 17.13.1 Overview
 17.13.2 Primary business
 17.13.3 Strategy
 17.13.4 Developments
  17.14 GYROS AB
 17.14.1 Overview
 17.14.2 Primary business
 17.14.3 Strategy
 17.14.4 Developments
  17.15 INCYTE CORP
 17.15.1 Overview
 17.15.2 Primary business
 17.15.3 Strategy
 17.15.4 Developments
  17.16 LIFE TECHNOLOGIES CORP
 17.16.1 Overview
 17.16.2 Primary business
 17.16.3 Strategy
 17.16.4 Developments
  17.17 SHIMADZU CORP
 17.17.1 Overview
 17.17.2 Primary business
 17.17.3 Strategy
 17.17.4 Developments
  17.18 PERKINELMER INC.
 17.18.1 Overview
 17.18.2 Primary business
 17.18.3 Strategy
 17.18.4 Developments
  17.19 SIGMA-ALDRICH CORP
 17.19.1 Overview
 17.19.2 Primary business
 17.19.3 Strategy
 17.19.4 Developments
  17.20 TECAN GROUP LTD.
 17.20.1 Overview
 17.20.2 Primary business
 17.20.3 Strategy
 17.20.4 Developments
  17.21 THERMO FISHER SCIENTIFIC INC.
 17.21.1 Overview
 17.21.2 Primary business
 17.21.3 Strategy
 17.21.4 Developments
 
APPENDIX  
 U.S. patents 
 EUROPE patents 
 JAPAN patents 

LIST OF TABLES  

1  Global top 10 drug discovery technologies market 2008 – 2015 ($Million) 
2  Estimated time saving by CRO in clinical trials 
3  Global high throughput screening market, by products 2008 – 2015 ($Million) 
4  High throughput screening market, by geography 2008 – 2015 ($Million) 
5  HTS infrastructural/resource comparison for pharmaceutical and academic centers 
6  Ultra high throughput screening market, by geography 2008 – 2015 ($Million) 
7  Robotics and automation market, by geography 2008 – 2015 ($Million) 
8  Miniaturization market, by geography 2008 – 2015 ($Million) 
9  High content screening market, by geography 2008 – 2015 ($Million) 
10 Cell based assays market, by geography 2008 – 2015 ($Million) 
11 Global bioanalytical instruments market, by products 2008 – 2015 ($Million) 
12 Bioanalytical instruments market, by geography 2008 – 2015 ($Million) 
13 Global mass spectrometry market, by products 2008 – 2015 ($Million) 
14 Mass spectrometry market, by geography 2008 – 2015 ($Million) 
15 Microplate Readers Market, By Geography 2008 – 2015 ($Million) 
16 NMR market, by geography 2008 – 2015 ($Million) 
17 Chemotherapy instruments market, by geography 2008 – 2015 ($Million) 
18 Pharmacogenomics market, by geography 2008 – 2015 ($Million) 
19 Combinatorial chemistry market, by geography 2008 – 2015 ($Million) 
20 Cost comparison between traditional and combinatorial chemistry 
21 Global genomics market, by products 2008 – 2015 ($Million) 
22 Genomics market, by geography 2008 – 2015 ($Million) 
23 Functional genomics market, by geography 2008 – 2015 ($Million) 
24 Structural genomics market, by geography 2008 – 2015 ($Million) 
25 Global biochips market, by segment 2008 – 2015 ($Million) 
26 Biochips market, by geography 2008 – 2015 ($Million) 
27 Patent disputes within the biochips market 
28 DNA microarrays market, by geography 2008 – 2015 ($Million) 
29 Lab on a chip market, by geography 2008 – 2015 ($Million) 
30 Proteomics microarrays market, by geography 2008 – 2015 ($Million) 
31 Global bioinformatics market, by products 2008 – 2015 ($Million) 
32 Bioinformatics market, by geography 2008 – 2015 ($Million) 
33 Global proteomics market, by products2008 – 2015 ($Million) 
34 Proteomics market, by geography 2008 – 2015 ($Million) 
35 2DGE market, by geography 2008 – 2015 ($Million) 
36 Two hybrid systems market, by geography 2008 – 2015 ($Million) 
37 Global RNAi market, by products 2008 – 2015 ($Million) 
38 RNAi market, by geography 2008 – 2015 ($Million) 
39 SiRNA market, by geography 2008 – 2015 ($Million) 
40 MiRNA market, by geography 2008 – 2015 ($Million) 
41 Global other RNAi technologies market, by products 2008 – 2015 ($Million) 
42 Other RNAi technologies market, by geography 2008 – 2015 ($Million) 
43 Global nanotechnology market, by products 2008 – 2015 ($Million) 
44 Nanotechnology market, by geography 2008 – 2015 ($Million) 
45 Comparison of AFM technology with other microscopy technology 
46 Atomic force microscopy market, by geography 2008 – 2015 ($Million) 
47 Nano-mass spectroscopy market, by geography 2008 – 2015 ($Million) 
48 Dip-pen Nanolithography market, by geography 2008 – 2015 ($Million) 
49 North American top 10 drug discovery technologies market 2008 – 2015 ($Million) 
50 European top 10 drug discovery technologies market 2008 – 2015 ($Million) 
51 Asian top 10 drug discovery technologies market 2008 – 2015 ($Million) 
52 RoW top 10 drug discovery technologies market 2008 – 2015 ($Million) 
53 Agreements and collaborations (2009 – 2010) 
54 New product development (2009 – 2010) 
 
LIST OF FIGURES
  
1 Revenue analysis for top 10 drug discovery technologies 
2 Top 10 drug discovery technologies market segmentation 
3 Relative market scenario (2010) 
4 Patent analysis by geography 
5 Patent analysis by competitors 2005 – 2010 
6 High throughput screening in drug discovery 
7 Approximate industrial demand for bioanalytical instruments (2010) 
8 Cost saving in comparison with high throughput screening 
9 Approximate end client share for microplate readers 
10 Drug development process and pharmacogenomics applications 
11 Future advancements in the pharmacogenomics research 
12 Cost associated with pharmacogenomics based tests 
13 Long term goals/benefits for pharmacogenomics 
14 Dollar value offered, by technology providers 
15 Time and cost saving by implementation of combinatorial chemistry 
16 Reducing costs for whole genome sequencing 
17 Major end clients for biochip technology market 
18 Historical data for DNA microarray based collaborations 
19 Applications of lab-on-a-chip technology in drug discovery 
20 MiRNA research efforts 
21 Applications areas of MiRNA 
22 MiRNA in drug discovery 
23 Nanotechnology applications 
24 Global market for top 10 drug discovery technologies 
25 Approximate market share for overall drug discovery technologies 
26 Approximate end client share for top 10 drug discovery technologies

Global Top 10 Drug Discovery Technologies Market

The top 10 drug discovery technologies play a vital role in the growth of the entire pharmaceutical industry, as they are the key contributors in the swift introduction of blockbusters and innovative drugs, which is the most important aspect for the pharmaceutical companies.

The applications of these technologies in the introduction of drugs for diverse diseases such as cancer, CVD, CNS disorders such as Parkinson’s and Alzheimer’s and other serious chronic diseases have created significant opportunities for the market growth in the future.

The slow growth of the introduction of new blockbuster drugs is a major concern which the drug development companies are catering to by using these top technologies. The increasing utilization of HTS in the lead generation and increasing adoption of the technology by the academia are some of the prime market boosters for high throughput screening.

The global top 10 drug discovery technologies market is expected to be around $ 30.8 billion in 2010 and estimated to reach $ 54 billion mark in 2015 growing at a CAGR of 11.9 % from 2010-2015. The market for high throughput screening accounts for the largest share with approximately 33% of the entire market for top 10 drug discovery technologies. This huge market share is mainly due to the increasing applications of cell based assays and robotics in the parallel screening of compounds.

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