HOME Top Market Reports Isothermal Nucleic Acid Amplification Technology (INAAT) Market by Application (Infectious Diseases, Blood Screening, Research), Products (Instruments, Reagents), End-User (Hospital, Reference Laboratories, Other) - Global Forecast to 2018

Isothermal Nucleic Acid Amplification Technology (INAAT) Market by Application (Infectious Diseases, Blood Screening, Research), Products (Instruments, Reagents), End-User (Hospital, Reference Laboratories, Other) - Global Forecast to 2018

By: marketsandmarkets.com
Publishing Date: May 2014
Report Code: BT 2491

 

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The global isothermal nucleic acid technology (INAAT) market is estimated to reach $1,651 million by 2018 at a CAGR of 13.5% during the forecast period. The market growth is primarily attributed to increasing demand for advanced isothermal based molecular testing over conventional thermal polymerase chain reaction (PCR) technology.

The study covers different product, application, and end-user segments of the global isothermal nucleic acid amplification technology market. The INAAT product segment is categorized into reagent and instrument sub-segments; whereas, the INAAT application segment is classified into infectious diseases, blood screening and research sub-segments. The scope of the end-users study of isothermal nucleic acid amplification technology includes hospitals, reference laboratories and others sub-segments.

Analysis for different market dynamics identified less expensive molecular testing using INAAT, increasing prevalence of infectious disease and cancer, growing demand for enhanced throughput in gene amplification, and advent of novel technologies such as Loop-Mediated Isothermal Amplification (LAMP), Nucleic Acid Sequence Based Amplification (NASBA) and Helicase Dependent Amplification (HDA) as the key driving factors of the global market. On the other hand, dominance of PCR technology and inadequate infrastructure hinder the market growth. The hand held device accessible POCT device is expected to capitalize on the diagnosis market for different infectious diseases such as tropical disease and sexually transmitted disease due to its low cost and rapid testing facility. Moreover, the advent of real time Chip based Nucleic Acid Testing (NAT) for SNP genotyping and cancer might encourage the adoption of INAAT due to its rapid turnaround time. Difficulties in developing lab-on-chip due to lack of multidisciplinary approach, and entry barrier in the PCR dominated emerging nations are considered the major challenges of the global market.

Amongst various application areas, INAAT is widely used for the detection of infectious diseases; it is expected to grow at the highest CAGR of 14.4% during the forecast period due to high incidence rate of various infectious diseases such as HIV and hepatitis A & B globally. On the other hand, rapid emergence of reference laboratories and rising importance of isothermal technology in different complex molecular testing are expected to ensure a significant adoption of technologies in reference laboratory.

North America commanded the largest market share of about 44% in 2013; whereas, Asian market is expected to grow at a higher CAGR during the forecast period. It is primarily due to increasing prevalence rate of infectious diseases and significant adoption of novel technologies. Capitalization on the unmet needs in infectious disease treatment market is expected to lure leading players to penetrate into emerging nations such as India, China, South Africa, Singapore, and Middle East.

Notable players in the global isothermal nucleic acid amplification technology market include Alere, Inc. (U.S.), Becton, Dickinson & Company (U.S.), BioHelix (U.S.), bioMerieux (France), Eiken Chemical Co. Ltd (Japan), Hologic Gene-Probe (U.S.), Lucigen (U.S.), Meridian Bioscience, Inc. (U.S.), New England Biolabs, Inc. (England), Novartis Diagnostics (Spain), Nugen (U.S.), QIAGEN (The Netherlands), and Ustar Biotechnologies, Ltd. (China).

Scope of the Report

This research report categorizes the global isothermal nucleic acid amplification technology market on the basis of products, application, end-user, and geography:

  • By Product:
    • Instruments
    • Reagents
  • By Application:
    • Infectious Diseases
    • Blood Screening
    • Research
  • By End-User:
    • Hospital
    • Reference Laboratories
    • Others
  • By Geography:
    • North America
    • Europe
    • Asia
    • Rest of the World

Table Of Content  
  
1 Introduction 
    1.1 Objectives Of The Study 
    1.2 Report Scope 
    1.3 Research Methodology 
    1.4 Key Data From Secondary & Primary Sources 
  
2 Executive Summary 
  
3 Technology Landscape Analysis 
    3.1 Technology Overview 
    3.2 INAAT Vs. Conventional Methods – Competitive Advantages 
    3.3 Technology Value Chain Analysis 
    3.4 Technology Capability and Maturity 
    3.5 Test Results General Nat Vs. INAAT Poct 
    3.6 Comparative Analysis Of INAAT Types 
  
4 Technology Investment Potential 
    4.1 Investment Climate Assessment  
          4.1.1 Investor Network 
                  4.1.1.1 Investment Climate Assessment 
                  4.1.1.2 Philanthropic Bodies 
                  4.1.1.3 Private Investors & Venture Capital Firms 
                  4.1.1.4 Insights on Current and Future Technology Investment Trends 
                  4.1.1.5 Some Of The Funds and Investments on INAAT 
    4.2 Evaluation Of Technologies Available For Licensing & Acquisition For Stakeholders 
    4.3 Analysis Of Potential Application Areas For Technology Investment Using Ose Grid 
          4.3.1 Ose - Parameters For Evaluation 
  
5 Market Landscape Analysis 
    5.1 Market Segmentation 
    5.2 Market Share in Molecular Diagnostics (Mdx) 
    5.3 Market Dynamics 
          5.3.1 Drivers – Description 
          5.3.2 Restraints – Description 
          5.3.3 Challenges – Description 
    5.4 Demand-Side Analysis 
  
6 Product Market 
    6.1 Product/Technology Innovations – Applications 
          6.1.1 Product/Technology Innovations – Applications 
                  6.1.1.1 INAAT Instrument Market – By Geography 
                  6.1.1.2 INAAT Reagent Market – By Geography 
  
7 Applications Market 
    7.1 INAAT & Molecular Diagnostics 
    7.2 Infectious Disease Diagnostics 
    7.3 Blood Screening 
    7.4 Laboratory Research  
    7.5 Cancer Research  
    7.6 Global INAAT Market – By Application (2013–2018) 
          7.6.1 INAAT Infectious Diseases Market, By Geography 
          7.6.2 INAAT Blood Screening Market – By Geography 
          7.6.3 INAAT Research Market – By Geography 
  
8 End-User Market 
    8.1 Global Isothermal Nucleic Acid Amplification Technology Market – By End User (2013–2018) 
    8.2 Global Market – By End User 
          8.2.1 INAAT Hospitals Market – By Geography 
          8.2.2 INAAT Reference Laboratories Market – By Geography 
          8.2.3 INAAT Other End-Users Market – By Geography 
    8.3 INAAT Market For Hospitals, By Application 
    8.4 INAAT Market For Reference Laboratories, By Application 
    8.5 INAAT Market For Other End Users, By Application 
  
9 Geographic Analysis 
    9.1 Technology Adoption & Development - Key Findings 
          9.1.1 Global Isothermal Nucleic Acid Amplification Technology Market - By Geography (2013–2018) 
    9.2 North America 
          9.2.1 North America – INAAT Market, By Application 
          9.2.2 North America – Market, By Product 
          9.2.3 North America – Market, By End User 
    9.3 Europe 
          9.3.1 Europe – INAAT Market, By Application 
          9.3.2 Europe – Market, By Product 
          9.3.3 Europe – Market, By End User 
    9.4 Asia 
          9.4.1 Asia – INAAT Market, By Application 
          9.4.2 Asia – Market, By Product 
          9.4.3 Asia – Market, By End User 
    9.5 Rest Of The World (ROW)  
          9.5.1 ROW– INAAT Market, By Application 
          9.5.2 ROW– Market, By Product 
          9.5.3 ROW– Market, By End User 
    9.6 Regions With High Technology Adoption 
  
10 Competitive Landscape 
    10.1 Partnerships, Collaborations & Agreements 
    10.2 New Product Launches 
    10.3 Mergers and Acquisitions 
  
11 Company Profiles 
    11.1 Alere 
    11.2 Becton, Dickinson and Company (Bd) 
    11.3 Biohelix 
    11.4 Biomerieux 
    11.5 Eiken Chemical Co., Ltd. 
    11.6 Hologic Gen-Probe 
    11.7 Lucigen 
    11.8 Meridian Bioscience, Inc. 
    11.9 New England Biolabs 
    11.10 Novartis Diagnostics 
    11.11 Nugen 
    11.12 Qiagen 
    11.13 Ustar Biotechnologies (Hangzhou) Ltd. 


List Of Tables (31 Tables)  

Table 1 NIH Funding Details and Estimation For Infectious Diseases During The Fiscal Year (Fy) 2010–2015 
Table 2 Gates Foundation Grants ($) (2010-2014) 
Table 3 Global Isothermal Nucleic Acid Amplification Technology Market, By Product, 2011–2018 ($Million) 
Table 4 INAAT Instruments Market, By Geography, 2011–2018 ($Million) 
Table 5 INAAT Reagents Market, By Geography, 2011–2018 ($Million) 
Table 6 Global Isothermal Nucleic Acid Amplification Technology Market, By Application, 2011–2018 ($Million) 
Table 7 INAAT Infectious Diseases Market,  By Geography, 2011–2018 ($Million) 
Table 8 INAAT Blood Screening Market, By Geography, 2011–2018 ($Million) 
Table 9 INAAT Research Market, By Geography, 2011–2018 ($Million) 
Table 10 Global Isothermal Nucleic Acid Amplification Technology Market, By End User, 2011–2018 ($Million) 
Table 11 INAAT Hospitals Market, By Geography, 2011–2018 ($Million) 
Table 12 INAAT Reference Laboratories Market, By Geography, 2011–2018 ($Million) 
Table 13 INAAT Other End-Users Market, By Geography, 2011–2018 ($Million) 
Table 14 INAAT Hospital Market Revenue, By Application, 2011–2018 ($Million) 
Table 15 INAAT Reference Laboratories Market Revenue, By Application, 2011–2018 ($Million) 
Table 16 INAAT Other End Users Market Revenue, By Application, 2011–2018 ($Million) 
Table 17 North America: Market, By Application, 2011–2018 ($Million) 
Table 18 North America:  Market, By Product, 2011–2018 ($Million) 
Table 19 North America: Market, By End User, 2011–2018 ($Million) 
Table 20 Europe: Market, By Application, 2011–2018 ($Million)  
Table 21 Europe: Market, By Product, 2011–2018 ($Million)  
Table 22 Europe: Market, By End User, 2011–2018 ($Million)  
Table 23 Asia: Market, By Application, 2011–2018 ($Million)  
Table 24 Asia: Market, By Product, 2011–2018 ($Million)  
Table 25 Asia: Market, By End User, 2011-2018 ($Million)  
Table 26 ROW: Market, By Application, 2011-2018 ($Million)  
Table 27 ROW: Market, By Product, 2011-2018 ($Million)  
Table 28 ROW: Market, By End User, 2011-2018 ($Million)  
Table 29 Partnerships, Collaborations & Agreements, 2011–2014 
Table 30 New Product Launches, 2011–2014 
Table 31 Mergers & Acquisitions, 2011–2014 


List Of Figures (53 Figure) 

Figure 1 Research Methodology  
Figure 2 INAAT Vs. Molecular Diagnostics: Market Revenue Forecast, 2011–2018 
Figure 3 Technology Evolution 
Figure 4 INAAT Vs. Conventional Methods – Competitive Advantages 
Figure 5 Technology Value Chain Analysis 
Figure 6 INAAT Capability Towards Poct 
Figure 7 Test Results General Nat Vs. INAAT Poct 
Figure 8 Comparative Analysis Of INAAT Types 
Figure 9 Technology Roadmap 
Figure 10 Attractive Forces For Increased Market Value 
Figure 11 Investor Network 
Figure 12 NIH Funds Towards Infectious Diseases 
Figure 13 Opportunity Strategic Evaluation Analysis 
Figure 14 Market Segmentation 
Figure 15 Market Share in Molecular Diagnostics (Mdx)  
Figure 16 Market Dynamics 
Figure 17 Drivers Impact – Timeline 
Figure 18 Restraints Impact – Timeline 
Figure 19 Current and Emerging Opportunities 
Figure 20 Demand-Side Analysis 
Figure 21 Market Share, By Product, 2013–2018  
Figure 22 Global Market, By Product, 2013 & 2018 ($Million) 
Figure 23 INAAT Instruments Market, By Geography, 2013 & 2018 ($Million) 
Figure 24 Global INAAT Reagents Market, By Geography, 2013 & 2018 ($Million) 
Figure 25 Isothermal Nucleic Acid Amplification Technology Applications Market 
Figure 26 INAAT Products Currently Available For Infectious Diseases  
Figure 27 Market Share, By Application, 2013–2018  
Figure 28 Global Market, By Application, 2013 & 2018 ($Million) 
Figure 29 INAAT Infectious Diseases Market, By Geography, 2013 & 2018 ($Million) 
Figure 30 INAAT Blood Screening Market,  By Geography, 2013 & 2018 ($Million) 
Figure 31 INAAT Research Market,  By Geography, 2013 & 2018 ($Million) 
Figure 32 Market Share, By End User, 2013–2018  
Figure 33 Global Market,  By End-User, 2013 & 2018 ($Million) 
Figure 34 INAAT Hospitals  Market, By Geography, 2013 & 2018 ($Million) 
Figure 35 INAAT Reference Laboratories  Market, By Geography, 2013 & 2018 ($Million) 
Figure 36 INAAT Other End-Users Market, By Geography, 2013 & 2018 ($Million) 
Figure 37 INAAT Hospital Market Revenue, By Application,  2013 Vs. 2018, ($Million) 
Figure 38 INAAT Reference Laboratories Market Revenue, By Application,  2013 Vs 2018 ($Million) 
Figure 39 INAAT Others End Users Market Revenue, By Application,  2013 Vs. 2018 ($Million) 
Figure 40 Market Share, By Geography, 2013–2018 
Figure 41 North America: Market, By Application,  2013 Vs. 2018 ($Million) 
Figure 42 North America:  Market, By Product, 2013 Vs.2018 ($Million) 
Figure 43 North America: Market, By End User, 2013 Vs. 2018 ($Million) 
Figure 44 Europe: Market, By Application, 2013 Vs.2018 ($Million)  
Figure 45 Europe: Market, By Product, 2013 Vs.2018 ($Million)  
Figure 46 Europe: Market, By End User, 2013 Vs.2018 ($Million)  
Figure 47 Asia: Market, By Application, 2013 Vs.2018 ($Million)  
Figure 48 Asia: Market, By Product, 2013 Vs.2018 ($Million)  
Figure 49 Asia: Market, By End User, 2013 Vs.2018 ($Million)  
Figure 50 ROW: Market, By Application, 2013 Vs.2018 ($Million)  
Figure 51 ROW: Market, By Product, 2013 Vs.2018 ($Million)  
Figure 52 ROW: Market, By End User, 2013 Vs.2018 ($Million)  
Figure 53 Key Growth Strategies Of The Global Isothermal Nucleic Acid Amplification Technologies Market, 2011–2014

The isothermal nucleic acid amplification technology (INAAT) market is poised to reach $1,651 million by 2018 at a CAGR of 13.5% during the forecast period. Despite the dominance of polymerase chain reaction (PCR) technology, INAAT is expected to seize a considerable market space in the global market since it enhances the quality of point-of-care testing using miniature DNA diagnostics.

Major driving factors of the global market includes increasing prevalence of infectious disease and cancer, promise for less expensive and better throughput in gene amplification using INAAT, and advent of novel technologies such as Loop-Mediated Isothermal Amplification (LAMP), Nucleic Acid Sequence Based Amplification (NASBA) and Helicase Dependent Amplification (HDA). However, inadequate automation and portability, and high dominance of PCR technology restrict the adoption of isothermal amplification technology globally.

Reagent segment held the maximum share of 70% of the global market in 2013; the segment is expected to grow at 14.7% CAGR due to increasing consumption of reagents in the detection of chronic diseases and genetic disorders. Future scope of market development lies in less expensive and portable POCT device as well as real time Chip based Nucleic Acid Testing (NAT) for SNP genotyping and cancer. Currently, difficulties in developing lab-on-chip due to lack of multidisciplinary approach, and high entry barrier in PCR dominated emerging nations restrict the market momentum in the developing countries.

Infectious disease was found to be the highest revenue generating segment (57.2%) of the global isothermal nucleic acid amplification technology market in 2013; it is expected to grow at a double digit growth during the forecast period. It is primarily attributed to high incidence rate of various infectious diseases such as HIV and hepatitis A & B, and increasing importance of INAAT in infection detection globally. Adoption of INAAT in blood screening application is also expected to grow as it ensures the quality of donated blood through its early prognosis of pathogen; whereas, cancer research, whole genome amplification, mutation, SNP detection and expression analysis are expected to drive the INAAT research application market.

Amongst different end-users, hospital segment accounts for the maximum share of the global end-user market in 2013. However, INAAT adoption in reference laboratories is expected to grow significantly due to increasing awareness of isothermal technology in different complex molecular testing.

North America contributed the largest market share of about 44% in 2013. On the other hand, increasing prevalence of infectious diseases and significant adoption of novel technologies are expected to drive the Asian market in the coming years. India, China, South Africa, Singapore, and Middle East were identified as the major focus areas amongst different emerging nations.

The notable players in the global isothermal nucleic acid amplification technology market include Alere, Inc. (U.S.), Becton, Dickinson & Company (U.S.), BioHelix (U.S.), bioMerieux (France), Hologic Gene-Probe (U.S.), and QIAGEN (The Netherlands).

Global INAAT market size snapshot, 2013 ($Million)

Isothermal Nucleic Acid Amplification Technologies Market, INAAT Market

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