Clinical Research Management System (CRMS) is a computer-based software system used to manage large amount of data related to clinical research planning, preparation, performance, and reporting. CRMS deals with the management of pharmacovigilance tasks, clinical trial management (CTMS), and regulatory filings management. It also helps to simplify the regulatory assessment and reporting process, thereby shortening the time taken to develop and market a new drug. CRMS is offered into three different delivery modes such as on-demand CRMS, (Saas) web-based CRMS, and cloud computing-based CRMS. Clinical Research Management System (CRMS) market is divided into three categories based on end-users such as provider CRMS market, pharmaceutical CRMS market, and Clinical Research Organizations (CRO) CRMS market. CRMS is mostly used by healthcare providers (academics/universities, hospitals, and research centers) who handle extensive clinical research projects that are complex as compared to the clinical trials. The application of CRMS will reduce both; the length and expenditure of the research. Moreover, clinical research projects are generally conducted concurrently over multiple geographies and making the right information accessible to the right people at the right time is of extreme importance and introduction of advanced CRMS will help in achieving this object. Effective management of clinical research stands as a priority to the research centers, academics/universities, and hospitals as they also involve huge investment and time.