Cartilage Repair Market / Cartilage Regeneration Market by Treatment modalities (Cell based Type (Chondrocyte Transplantation, Growth Factor), Non-Cell (Tissue Scaffolds)), Application (Hyaline), End User (ASCs, Clinic), Site (Knee) & Region - Global Forecasts to 2025
Updated on : February 22, 2023
The global cartilage repair market in terms of revenue was estimated to be worth $787 million in 2020 and is poised to reach $1,603 million by 2025, growing at a CAGR of 15.3% from 2020 to 2025. The growth of this market is primarily driven by the increasing incidence of osteoarthritis and increasing funding and investments for research in this field.
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Cartilage Repair Market Dynamics
Drivers: Increasing incidence of osteoarthritis
Over the years, the incidence of osteoarthritis has increased across the globe. According to a study by the University of North Carolina, around 1 million knee and hip replacement procedures are conducted every year in the US. The economic burden of osteoarthritis in the US is ~136.8 billion annually. As per the Arthritis Foundation in 2019, degenerative joint diseases such as osteoarthritis will affect more than 130 million patients worldwide by 2050.
Some of the most commonly used treatments for osteoarthritis are autologous chondrocyte implantation and Scaffolds implants Thus, the increasing incidence of osteoarthritis is expected to drive the demand for cartilage repair and regeneration products.
Restraints: High cost of cartilage repair surgeries
Although cartilage repair surgeries offer better and long-lasting results as compared to total knee replacement surgeries, the cost of these therapies is one of the major factors limiting their adoption among patients. The average cost for knee replacement procedures is around USD 16,000, while the average cost of cartilage repair procedures is around USD 18,000–USD 23,000, depending on the region where the procedure is being performed. Such high costs underrate the results of cartilage repair therapies, and in turn, result in a lower preference for these procedures as compared to knee replacement surgeries.
Opportunities: Technological advancements
As a result of the rising government investments in regenerative medicine for cartilage regeneration research, the number of companies focusing on the development of cartilage regeneration products has increased significantly over the last few years. As a result of these factors, the number of clinical trials and the development of new technologies for cartilage regeneration has increased. Major players in this market are making significant investments in R&D, resulting in a strong pipeline of products based on various approaches to cartilage repair.
Challenges: Limitation of cartilage-based stem cell products
Active research is ongoing to identify an exhaustive universal source of progenitor cells, such as embryonic stem cells and induced pluripotent stem cells, for cartilage repair and regeneration. However, there are major challenges associated with their clinical use due to ethical considerations and safety issues, such as immune rejection, tumorigenesis, and teratoma formation. In order to monitor these activities, strict regulations have been formulated by authorities such as the Human Tissue Authority (HTA), Human Fertilization and Embryology Authority (HFEA), Medicines and Healthcare Products Regulatory Agency (MHRA), and the Central Ethics Committee for Stem Cell Research. Due to the presence of these organizations, coupled with the ethical concerns on the use of embryonic stem cells in research and development activities, regenerative medicine research is being restricted to a great extent in various countries across the globe. Other issues related to the effective use of stem cells include reduced potentiality with age and disease and production of fibrocartilage instead of hyaline cartilage at the site of damage. With stringent regulations in place, a large number of products under development do not proceed to the marketing approval stage as they cannot clear the safety and efficacy requirements.
By end user segment, the hospitals segment accounted for the largest share of the cartilage repair market in 2019.
Based on end users, the cartilage regeneration market is segmented into hospitals and ambulatory surgery centers (ASCs) and clinics. The hospitals segment accounted for the largest share of the global market in 2019. This can be attributed to the large number of minimally invasive surgeries performed in hospitals and the growing number of hospitals in emerging economies.
By application site, the knee segment accounted for the largest share of the cartilage repair market in 2019.
Based on the application site, the cartilage regeneration market is segmented into knee, hip, ankle and foot, and other application sites (nose and shoulder). The knee segment accounted for the largest share of application site segment of the global market in 2019. This can be attributed to the growing number of knee arthroscopy procedures and the increasing incidence of knee osteoarthritis.
North America accounted for the largest share of the cartilage repair market in 2019.
In 2019, North America accounted for the largest share of the global market, followed by Europe. The large share of the North American region can be attributed to the high burden of osteoarthritis, increasing prevalence of sports injuries, and increasing research investments in the US and Canada.
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The cartilage repair market is dominated by a few globally established players such as Smith & Nephew plc (UK), DePuy Synthes (US), Zimmer Biomet (US), CONMED Corporation (US), Stryker Corporation (US), and Vericel Corporation (US).
Cartilage Regeneration Market Report Scope:
|
Report Metric |
Details |
|
Market Size Available for Years |
2018–2025 |
|
Base Year Considered |
2019 |
|
Forecast Period |
2020–2025 |
|
Forecast Units |
Value (USD) |
|
Segments Covered |
Application, Treatment Modality, Application Site, End user, and Region |
|
Geographies Covered |
North America, Europe, APAC and the RoW |
|
Companies Covered |
The major market players include DePuy Synthes (US), Smith & Nephew plc (UK), Zimmer Biomet (US), CONMED Corporation (US), Stryker Corporation (US), and Vericel Corporation (US). (Total 16 companies)
|
The study categorizes the cartilage repair market market into the following segments and sub-segments:
By Treatment Modality
-
Cell-based
- Chondrocyte Transplantation
- Stem Cells
- Growth Factors
-
Non-cell-based
- Tissue Scaffolds
- Cell-free Composites
By Application
- Hyaline Cartilage
- Fibrocartilage
By Application Site
- Knee
- Hip
- Ankle and Foot
- Other Application Sites
By End User
- Hospitals
- Ambulatory Surgery Centers and Clinics
By Region
-
North America
- US
- Canada
-
Europe
- Germany
- France
- UK
- Rest of Europe
-
Asia Pacific
- Japan
- China
- India
- Rest of Asia Pacific
- Rest of the World
Recent Developments
- In 2019, Smith & Nephew acquired Osiris Therapeutics, Inc. (US). This acquisition increased the company’s customer base and enhanced the advanced wound care management segment of Smith & Nephew.
- In 2019, MEDIPOST (South Korea) expanded the GMP manufacturing facility to accelerate CARTISTEM production.
- In 2018, Vericel Corporation collaborated with Innovative Cellular Therapeutics (ICT, China), under this collaboration, ICT will develop and distribute MACI, Epicel, Ixmyelocel-T, and Carticel products in China, South Korea, Singapore, and other countries in Asia.
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TABLE OF CONTENTS
1 INTRODUCTION (Page No. - 26)
1.1 OBJECTIVES OF THE STUDY
1.2 MARKET DEFINITION
TABLE 1 INCLUSIONS & EXCLUSIONS
1.3 MARKET SCOPE
FIGURE 1 MARKETS COVERED
1.3.1 YEARS CONSIDERED FOR THE STUDY
1.4 CURRENCY
1.5 LIMITATIONS
1.6 STAKEHOLDERS
1.7 SUMMARY OF CHANGES
2 RESEARCH METHODOLOGY (Page No. - 30)
2.1 RESEARCH DATA
2.1.1 SECONDARY DATA
2.1.2 PRIMARY DATA
FIGURE 2 BREAKDOWN OF PRIMARIES: CARTILAGE REPAIR MARKET
2.1.3 MARKET DATA ESTIMATION & TRIANGULATION
2.1.3.1 Data Triangulation
FIGURE 3 DATA TRIANGULATION METHODOLOGY
2.2 MARKET ESTIMATION METHODOLOGY
FIGURE 4 MARKET SIZE ESTIMATION APPROACH 1: COMPANY REVENUE ANALYSIS-BASED ESTIMATION
FIGURE 5 MARKET SIZE ESTIMATION APPROACH 2: TOP-DOWN APPROACH
FIGURE 6 CARTILAGE REPAIR AND REGENERATION MARKET SIZE (USD MILLION)
2.3 GROWTH RATE ASSUMPTIONS/GROWTH FORECAST
FIGURE 7 SEGMENTAL GROWTH RATE OF COMPANIES (2015−2019)
FIGURE 8 FINAL CAGR PROJECTIONS (2020−2025)
FIGURE 9 CAGR PROJECTIONS FROM THE ANALYSIS OF DEMAND-SIDE DRIVERS AND OPPORTUNITIES
2.4 INSIGHTS FROM PRIMARIES
FIGURE 10 MARKET VALIDATION FROM PRIMARY EXPERTS
2.5 RESEARCH ASSUMPTIONS
2.6 RISK ASSESSMENT
TABLE 2 RISK ASSESSMENT
3 EXECUTIVE SUMMARY (Page No. - 39)
FIGURE 11 CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY
FIGURE 12 CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2020—2025
FIGURE 13 CARTILAGE REPAIR AND REGENERATION MARKET SHARE, BY END USER, 2019
FIGURE 14 GEOGRAPHICAL SNAPSHOT OF THE CARTILAGE REPAIR AND REGENERATION MARKET
4 PREMIUM INSIGHTS (Page No. - 42)
4.1 CARTILAGE REPAIR MARKET OVERVIEW
FIGURE 15 RISING INCIDENCE OF OSTEOARTHRITIS TO DRIVE MARKET GROWTH
4.2 ASIA PACIFIC: CARTILAGE REPAIR AND REGENERATION MARKET, BY TREATMENT MODALITY AND COUNTRY (2019)
FIGURE 16 CELL-BASED SEGMENT ACCOUNTED FOR THE LARGEST SHARE OF THE ASIA PACIFIC MARKET IN 2019
4.3 CARTILAGE REPAIR AND REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE (2020–2025)
FIGURE 17 CHONDROCYTE TRANSPLANTATION SEGMENT WILL CONTINUE TO DOMINATE THE MARKET IN THE FORECAST PERIOD
4.4 CARTILAGE REGENERATION MARKET SHARE, BY APPLICATION, 2020 VS. 2025
FIGURE 18 HYALINE CARTILAGE IS THE LARGEST APPLICATION SEGMENT OF THE CARTILAGE REPAIR AND REGENERATION MARKET
4.5 CARTILAGE REPAIR AND REGENERATION MARKET, BY APPLICATION SITE, 2020 VS. 2025 (USD MILLION)
FIGURE 19 THE KNEE SEGMENT WILL CONTINUE TO DOMINATE THE CARTILAGE REPAIR AND REGENERATION MARKET IN 2025
5 MARKET OVERVIEW (Page No. - 46)
5.1 INTRODUCTION
5.2 MARKET DYNAMICS
FIGURE 20 CARTILAGE REGENERATION MARKET: DRIVERS, RESTRAINTS, OPPORTUNITIES, AND CHALLENGES
5.2.1 MARKET DRIVERS
5.2.1.1 Increasing incidence of osteoarthritis
5.2.1.2 Increasing research funding and investments
5.2.2 RESTRAINTS
5.2.2.1 High cost of cartilage repair surgeries
5.2.3 OPPORTUNITIES
5.2.3.1 Technological advancements
5.2.4 CHALLENGES
5.2.4.1 Limitation of cartilage-based stem cell products
5.3 SUPPLY CHAIN ANALYSIS
FIGURE 21 SUPPLY CHAIN ANALYSIS OF THE CARTILAGE REPAIR AND REGENERATION MARKET
5.4 IMPACT OF THE COVID-19 OUTBREAK ON THE GROWTH OF THE CARTILAGE REPAIR AND REGENERATION MARKET
FIGURE 22 COVID-19 IMPACT ON THE CARTILAGE REPAIR AND REGENERATION MARKET
5.5 REGULATORY ASSESSMENT
5.5.1 INTRODUCTION
5.5.2 NORTH AMERICA
5.5.3 EUROPE
5.5.4 ASIA PACIFIC
5.6 PATENT ANALYSIS
5.6.1 DOCUMENT TYPE
TABLE 3 PATENTS FILED
FIGURE 23 PATENTS FILED (2016—2020)
FIGURE 24 PATENTS FILED BETWEEN 2016 AND AUGUST 2020
5.6.2 INSIGHTS
FIGURE 25 JURISDICTION ANALYSIS (2019)
5.6.3 TOP APPLICANTS (2019)
5.7 PIPELINE ANALYSIS
5.7.1 BASED ON THE PHASE OF CLINICAL TRIAL
FIGURE 26 MAJORITY OF CARTILAGE REPAIR CANDIDATE PRODUCTS ARE IN PHASE 3
5.8 TECHNOLOGY ANALYSIS
6 CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY (Page No. - 59)
6.1 INTRODUCTION
TABLE 4 CARTILAGE REPAIR AND REGENERATION MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
6.2 CELL-BASED
TABLE 5 CARTILAGE REPAIR AND REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 6 CARTILAGE REPAIR AND REGENERATION MARKET FOR CELL-BASED APPROACHES, BY REGION, 2018–2025 (USD MILLION)
TABLE 7 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR CELL-BASED APPROACHES, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 8 EUROPE: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 9 APAC: CARTILAGE REPAIR AND REGENERATION MARKET FOR CELL-BASED APPROACHES, BY COUNTRY, 2018–2025 (USD MILLION)
6.2.1 CHONDROCYTE TRANSPLANTATION
6.2.1.1 Cost-effectiveness of chondrocyte transplantation to support market growth
TABLE 10 CHONDROCYTE TRANSPLANTATION MARKET, BY REGION, 2018–2025 (USD MILLION)
TABLE 11 NORTH AMERICA: CHONDROCYTE TRANSPLANTATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
6.2.2 GROWTH FACTORS
6.2.2.1 Promising results associated with growth factors is the major factor driving the growth of this segment
TABLE 12 GROWTH FACTORS MARKET, BY REGION, 2018–2025 (USD MILLION)
TABLE 13 NORTH AMERICA: GROWTH FACTORS MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
6.2.3 STEM CELLS
6.2.3.1 Advancements in stem cell-based tissue engineering will drive the growth of this segment
TABLE 14 STEM CELLS MARKET, BY REGION, 2018–2025 (USD MILLION)
TABLE 15 NORTH AMERICA: STEM CELLS MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
6.3 NON-CELL-BASED
TABLE 16 CARTILAGE REPAIR AND REGENERATION MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 17 CARTILAGE REPAIR AND REGENERATION MARKET FOR NON-CELL-BASED APPROACHES, BY REGION, 2018–2025 (USD MILLION)
TABLE 18 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR NON-CELL-BASED APPROACHES, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 19 EUROPE: CARTILAGE REPAIR AND REGENERATION MARKET FOR NON-CELL-BASED APPROACHES, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 20 APAC: CARTILAGE REPAIR AND REGENERATION MARKET FOR NON-CELL-BASED APPROACHES, BY COUNTRY, 2018–2025 (USD MILLION)
6.3.1 TISSUE SCAFFOLDS
6.3.1.1 Benefits of the one-step procedure likely to boost the market growth
TABLE 21 TISSUE SCAFFOLDS MARKET, BY REGION, 2018–2025 (USD MILLION)
6.3.2 CELL-FREE COMPOSITES
6.3.2.1 Increasing research to support market growth
TABLE 22 CELL-FREE COMPOSITES MARKET, BY REGION, 2018–2025 (USD MILLION)
7 CARTILAGE REPAIR MARKET, BY APPLICATION SITE (Page No. - 68)
7.1 INTRODUCTION
TABLE 23 CARTILAGE REGENERATION MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
7.2 KNEE
7.2.1 INCREASING CASES OF KNEE ARTHROSCOPY TO DRIVE MARKET GROWTH
TABLE 24 CARTILAGE REPAIR AND REGENERATION MARKET FOR KNEE, BY REGION, 2018–2025 (USD MILLION)
TABLE 25 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR KNEE, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 26 EUROPE: CARTILAGE REPAIR AND REGENERATION MARKET FOR KNEE, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 27 APAC: CARTILAGE REPAIR AND REGENERATION MARKET FOR KNEE, BY COUNTRY, 2018–2025 (USD MILLION)
7.3 HIP
7.3.1 INCREASING ADOPTION OF MINIMALLY INVASIVE ARTHROSCOPY PROCEDURES TO SUPPORT MARKET GROWTH
TABLE 28 CARTILAGE REPAIR AND REGENERATION MARKET FOR HIP, BY REGION, 2018–2025 (USD MILLION)
TABLE 29 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR HIP, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 30 EUROPE: CARTILAGE REPAIR AND REGENERATION MARKET FOR HIP, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 31 APAC: CARTILAGE REPAIR AND REGENERATION MARKET FOR HIP, BY COUNTRY, 2018–2025 (USD MILLION)
7.4 ANKLE & FOOT
7.4.1 INCREASING SPORTS INJURIES IN THE ANKLE & FOOT ARE LIKELY TO DRIVE THE DEMAND FOR CARTILAGE REPAIR PROCEDURES
TABLE 32 CARTILAGE REPAIR AND REGENERATION MARKET FOR ANKLE & FOOT, BY REGION, 2018–2025 (USD MILLION)
TABLE 33 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR ANKLE & FOOT, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 34 EUROPE: CARTILAGE REPAIR AND REGENERATION MARKET FOR ANKLE & FOOT, BY COUNTRY, 2018–2025 (USD MILLION)
7.5 OTHER APPLICATION SITES
TABLE 35 CARTILAGE REPAIR AND REGENERATION MARKET FOR OTHER APPLICATION SITES, BY REGION, 2018–2025 (USD MILLION)
TABLE 36 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR OTHER APPLICATION SITES, BY COUNTRY, 2018–2025 (USD MILLION)
8 CARTILAGE REPAIR MARKET, BY APPLICATION (Page No. - 75)
8.1 INTRODUCTION
TABLE 37 CARTILAGE REGENERATION MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
8.2 HYALINE CARTILAGE
8.2.1 HYALINE CARTILAGE SEGMENT HOLDS THE LARGER MARKET SHARE
TABLE 38 HYALINE CARTILAGE REPAIR AND REGENERATION MARKET, BY REGION, 2018–2025 (USD MILLION)
TABLE 39 NORTH AMERICA: HYALINE CARTILAGE REPAIR AND REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 40 EUROPE: HYALINE CARTILAGE REPAIR AND REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 41 APAC: HYALINE CARTILAGE REPAIR AND REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
8.3 FIBROCARTILAGE
8.3.1 FIBROCARTILAGE PROVIDES SUPPORT AND RIGIDITY TO SURROUNDING STRUCTURES
TABLE 42 FIBROCARTILAGE REPAIR AND REGENERATION MARKET, BY REGION, 2018–2025 (USD MILLION)
TABLE 43 NORTH AMERICA: FIBROCARTILAGE REPAIR AND REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 44 EUROPE: FIBROCARTILAGE REPAIR AND REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 45 APAC: FIBROCARTILAGE REPAIR AND REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
9 CARTILAGE REPAIR MARKET, BY END USER (Page No. - 80)
9.1 INTRODUCTION
TABLE 46 CARTILAGE REGENERATION MARKET, BY END USER, 2018–2025 (USD MILLION)
9.2 HOSPITALS
9.2.1 HOSPITALS ARE THE LARGEST & FASTEST-GROWING END USERS OF THE MARKET
TABLE 47 CARTILAGE REPAIR AND REGENERATION MARKET FOR HOSPITALS, BY REGION, 2018–2025 (USD MILLION)
TABLE 48 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR HOSPITALS, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 49 EUROPE: CARTILAGE REPAIR AND REGENERATION MARKET FOR HOSPITALS, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 50 APAC: CARTILAGE REPAIR AND REGENERATION MARKET FOR HOSPITALS, BY COUNTRY, 2018–2025 (USD MILLION)
9.3 AMBULATORY SURGERY CENTERS & CLINICS
9.3.1 RISING PREFERENCE FOR PERFORMING SURGERIES IN ASCS IS SUPPORTING THE GROWTH OF THIS SEGMENT
TABLE 51 CARTILAGE REPAIR AND REGENERATION MARKET FOR ASCS & CLINICS, BY REGION, 2018–2025 (USD MILLION)
TABLE 52 NORTH AMERICA: CARTILAGE REPAIR AND REGENERATION MARKET FOR ASCS & CLINICS, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 53 EUROPE: CARTILAGE REPAIR AND REGENERATION MARKET FOR ASCS & CLINICS, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 54 APAC: CARTILAGE REPAIR AND REGENERATION MARKET FOR ASCS & CLINICS, BY COUNTRY, 2018–2025 (USD MILLION)
10 CARTILAGE REPAIR MARKET, BY REGION (Page No. - 85)
10.1 INTRODUCTION
FIGURE 27 CARTILAGE REGENERATION MARKET, BY REGION, 2020 VS. 2025 (USD MILLION)
TABLE 55 GLOBAL MARKET, BY REGION, 2018–2025 (USD MILLION)
10.2 NORTH AMERICA
FIGURE 28 NORTH AMERICA: CARTILAGE REPAIR MARKET SNAPSHOT
TABLE 56 NORTH AMERICA: CARTILAGE REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 57 NORTH AMERICA: MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 58 NORTH AMERICA: MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 59 NORTH AMERICA: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 60 NORTH AMERICA: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 61 NORTH AMERICA: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 62 NORTH AMERICA: MARKET, BY APPLICATION SITE, 2018–2025(USD MILLION)
10.2.1 US
10.2.1.1 Increasing incidence of obesity is the major factor supporting the market growth in the US
TABLE 63 US: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 64 US: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 65 US: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 66 US: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 67 US: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 68 US: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.2.2 CANADA
10.2.2.1 Increasing investments in regenerative medicine research to drive market growth
TABLE 69 CANADA: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 70 CANADA: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 71 CANADA: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 72 CANADA: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 73 CANADA: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 74 CANADA: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.3 EUROPE
TABLE 75 EUROPE: CARTILAGE REPAIR MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 76 EUROPE: CARTILAGE REGENERATION MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 77 EUROPE: MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 78 EUROPE: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 79 EUROPE: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 80 EUROPE: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 81 EUROPE: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.3.1 GERMANY
10.3.1.1 Strong R&D base and focus on minimally invasive surgeries to support market growth
TABLE 82 GERMANY: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 83 GERMANY: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 84 GERMANY: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 85 GERMANY: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 86 GERMANY: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 87 GERMANY: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.3.2 UK
10.3.2.1 Rising number of clinical trials in the UK to drive market growth
TABLE 88 UK: CARTILAGE REPAIR AND REGENERATION PRODUCTS UNDER CLINICAL TRIALS
TABLE 89 UK: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 90 UK: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 91 UK: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 92 UK: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 93 UK: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 94 UK: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.3.3 FRANCE
10.3.3.1 Rising healthcare expenditure in the country to drive market growth
TABLE 95 FRANCE: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 96 FRANCE: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 97 FRANCE: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 98 FRANCE: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 99 FRANCE: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 100 FRANCE: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.3.4 REST OF EUROPE
TABLE 101 ROE: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 102 ROE: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 103 ROE: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 104 ROE: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 105 ROE: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 106 ROE: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.4 ASIA PACIFIC
FIGURE 29 ASIA PACIFIC: CARTILAGE REPAIR MARKET
TABLE 107 APAC: CARTILAGE REGENERATION MARKET, BY COUNTRY, 2018–2025 (USD MILLION)
TABLE 108 APAC: MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 109 APAC: MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 110 APAC: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 111 APAC: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 112 APAC: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 113 APAC: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.4.1 JAPAN
10.4.1.1 Rising geriatric population is the major factor supporting market growth in Japan
TABLE 114 JAPAN: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 115 JAPAN: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 116 JAPAN: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 117 JAPAN: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 118 JAPAN: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 119 JAPAN: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.4.2 CHINA
10.4.2.1 China forms the fastest-growing market in the APAC
TABLE 120 CHINA: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 121 CHINA: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 122 CHINA: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 123 CHINA: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 124 CHINA: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 125 CHINA: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.4.3 INDIA
10.4.3.1 Medical tourism will propel market growth in India
TABLE 126 INDIA: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 127 INDIA: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 128 INDIA: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 129 INDIA: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 130 INDIA: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 131 INDIA: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.4.4 REST OF ASIA PACIFIC
TABLE 132 ROAPAC: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 133 ROAPAC: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 134 ROAPAC: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 135 ROAPAC: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 136 ROAPAC: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 137 ROAPAC: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
10.5 REST OF THE WORLD
TABLE 138 ROW: CARTILAGE REPAIR MARKET, BY TREATMENT MODALITY, 2018–2025 (USD MILLION)
TABLE 139 ROW: CARTILAGE REGENERATION MARKET FOR CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 140 ROW: MARKET FOR NON-CELL-BASED APPROACHES, BY TYPE, 2018–2025 (USD MILLION)
TABLE 141 ROW: MARKET, BY END USER, 2018–2025 (USD MILLION)
TABLE 142 ROW: MARKET, BY APPLICATION, 2018–2025 (USD MILLION)
TABLE 143 ROW: MARKET, BY APPLICATION SITE, 2018–2025 (USD MILLION)
11 COMPETITIVE LANDSCAPE (Page No. - 122)
11.1 INTRODUCTION
11.2 MARKET RANKING ANALYSIS
FIGURE 30 CARTILAGE REPAIR MARKET RANKING, 2019
11.2.1 MARKET REVENUE ANALYSIS (2015–2019)
FIGURE 31 REVENUE ANALYSIS OF MAJOR PLAYERS (2015−2019)
11.3 MARKET EVALUATION FRAMEWORK
TABLE 144 MARKET EVALUATION FRAMEWORK: PRODUCT LAUNCH—THE MAJOR STRATEGY ADOPTED BY PLAYERS
11.4 COMPETITIVE SCENARIO
11.4.1 KEY PRODUCT LAUNCHES
11.4.2 KEY ACQUISITIONS
11.4.3 KEY COLLABORATIONS
11.4.4 KEY EXPANSIONS
11.5 COMPANY EVALUATION MATRIX
11.5.1 STARS
11.5.2 EMERGING LEADERS
11.5.3 PARTICIPANTS
11.5.4 PERVASIVE
FIGURE 32 CARTILAGE REGENERATION MARKET: COMPETITIVE EVALUATION MATRIX (2019)
12 COMPANY PROFILES (Page No. - 127)
(Business overview, Products offered, Recent Developments, SWOT analysis, MNM view)*
12.1 SMITH & NEPHEW PLC
FIGURE 33 SMITH & NEPHEW: COMPANY SNAPSHOT (2019)
12.2 DEPUY SYNTHES
FIGURE 34 JOHNSON & JOHNSON: COMPANY SNAPSHOT (2019)
12.3 ZIMMER BIOMET HOLDINGS, INC.
FIGURE 35 ZIMMER BIOMET: COMPANY SNAPSHOT (2019)
12.4 STRYKER CORPORATION
FIGURE 36 STRYKER CORPORATION: COMPANY SNAPSHOT (2019)
12.5 VERICEL CORPORATION
FIGURE 37 VERICEL CORPORATION: COMPANY SNAPSHOT (2019)
12.6 B. BRAUN MELSUNGEN AG
FIGURE 38 B. BRAUN MELSUNGEN AG: COMPANY SNAPSHOT (2019)
12.7 ANIKA THERAPEUTICS
FIGURE 39 ANIKA THERAPEUTICS: COMPANY SNAPSHOT (2019)
12.8 RTI SURGICAL
12.9 CONMED CORPORATION
FIGURE 40 CONMED CORPORATION: COMPANY SNAPSHOT (2019)
12.10 ARTHREX, INC.
12.11 REGROW BIOSCIENCES
12.12 MEDIPOST
FIGURE 41 MEDIPOST: COMPANY SNAPSHOT (2019)
12.13 GEISTLICH PHARMA AG
12.14 ALLOSOURCE
12.15 ORTHOCELL LTD.
12.16 BIOTISSUE SA
*Details on Business overview, Products offered, Recent Developments, SWOT analysis, MNM view might not be captured in case of unlisted companies.
13 APPENDIX (Page No. - 151)
13.1 DISCUSSION GUIDE
13.2 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL
13.3 AVAILABLE CUSTOMIZATIONS
13.4 RELATED REPORTS
13.5 AUTHOR DETAILS
This market research study involves the extensive use of secondary sources, directories, and databases to identify and collect information useful for this technical, market-oriented, and financial study of the global cartilage repair market. In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, among other experts, to obtain and verify critical qualitative and quantitative information and assess market prospects. The size of the cartilage regeneration market was estimated through various secondary research approaches and triangulated with inputs from primary research to arrive at the final market size.
Secondary Research
The secondary sources referred to for this research study include publications from government sources, such as World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), US Food and Drug Administration (FDA), and International Cartilage Regeneration & Joint Preservation Society (ICRS), Asian Cartilage Repair Society, Alliance for Regenerative Medicine; secondary sources such as corporate and regulatory filings (such as annual reports, SEC filings, investor presentations, and financial statements); business magazines and research journals; press releases; and trade, business, and professional associations. Secondary data was collected and analyzed to arrive at the overall size of the global cartilage repair market, which was validated through primary research.
Primary Research
Extensive primary research was conducted after acquiring basic knowledge about the global cartilage regeneration market scenario through secondary research. Several primary interviews were conducted with market experts from both the demand (such as personnel from the pharmaceutical and biopharmaceutical industry) and supply sides (such as C-level and D-level executives, product managers, marketing and sales managers of key manufacturers, and distributors) across four major regions—North America, Europe, Asia Pacific, and the Rest of the World. Approximately 80% and 20% of primary interviews were conducted with supply-side and demand-side participants, respectively. This primary data was collected through questionnaires, e-mails, online surveys, personal interviews, and telephonic interviews.
To know about the assumptions considered for the study, download the pdf brochure
Data Triangulation
After arriving at the overall market size of the global cartilage repair market through the methodology mentioned above, this market was split into several segments and subsegments. Market breakdown procedures were employed, wherever applicable, to arrive at the exact market value for the key segments and subsegments. The extrapolated market data was triangulated by studying various macroindicators and regional trends from both demand- and supply-side participants.
Report Objectives
- To define, describe, and forecast the cartilage repair market based on application, treatment modality, application site, end user, and region
- To provide detailed information about the major factors influencing the market growth (such as drivers, opportunities, restraints, and challenges)
- To strategically analyze micromarkets1 with respect to individual growth trends, prospects, and contributions to the overall cartilage regeneration market
- To analyze market opportunities for stakeholders and provide details of the competitive landscape for key players
- To forecast the size of the market segments with respect to five major regions, namely, North America, Europe, Asia Pacific (APAC), and the Rest of the World
- To profile the key players and comprehensively analyze their core competencies2 in terms of key developments, product portfolios, and financials
- To track and analyze competitive developments such as product launches, agreements, partnerships, collaborations, acquisitions, and expansions in the cartilage regeneration market
Available Customizations
With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for the report:
Geographic Analysis
- Further breakdown of the APAC cartilage repair market, by country.
- Further breakdown of the European cartilage repair market into Spain and Italy.
Generating Response ...
Growth opportunities and latent adjacency in Cartilage Repair Market