Cryo-electron Microscopy Market by Product & Service (Instruments, Software, Services), Technology (Electron Crystallography, Cryo-ET), Voltage (300 kV), Application (Cancer, Omics, Gene Therapy, Nanotechnology, Vaccine) & Region - Global Forecasts to 2028
Updated on : March 03, 2023
The global cryo-electron microscopy market in terms of revenue was estimated to be worth $1.1 billion in 2022 and is poised to reach $2.1 billion by 2028, growing at a CAGR of 11.6% from 2022 to 2028. The increasing focus on nanotechnology has risen the use of cryo-electron microscopes globally. Different academic and research institutes has increased the adoption of technologically advanced cryo-electron microscopes.
Global Cryo-Electron Microscopy Market
e- Estimated; p- Projected
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Cryo-electron Microscopy Market Dynamics
Drivers: Technological advancements in cryo-electron microscopes
Recent years have seen significant advancements in cryo-electron microscopes, such as developments in direct electron detectors (DEDs) and data analysis software such as cryoSPARC, SerialEM, and CryoDiscovery. These technologically advanced detectors have improved sensors and detect electrons at increased frame rates with higher detector quantum efficiency (DQE). Recent advancements have also eliminated the challenges associated with sample preparation. These advancements has increased the popularity of the instruments in different sectors such as pharmaceutical & biotech industries and research institutes.
- Restraints: High equipment costs
Recent technological advancements, newly added features, and high resolution have increased the popularity of cryo-electron microscopes. There is a consistent rise in the cost of these systems with the addition of sample preparation & transfer systems and customized software for analyzing the generated images. The basic software solution is priced low but the software with advanced features and specific applications is often costly. In addition, there are recurrent expenses in the form of maintenance costs, which ultimately drive up the overall cost of ownership. This high cost has left users reliant on government and private research funding, which restricts market growth to a certain extent.
Opportunities: Growing opportunities in emerging markets
Developing countries, including China, India, Russia, and Brazil, offer significant growth opportunities for players in the microscopy market. Government funding for R&D in advanced microscopes has increased considerably in these countries. In addition to government funding, original equipment manufacturers (OEMs) in emerging markets provide opportunities for key players to outsource their microscopy products as a cost-saving strategy. Increasing use of cryo-electron microscopy technique for structural analysis of proteins and other biomolecules at an atomic scale for various applications in life science research is driving the growth of the market.
Challenges: Shortage of skilled professionals
Skilled personnel are required to use advanced cryo-electron microscopes. High-end microscopes are required to be maintained properly. This requires qualified service engineers to ensure optimal performance. The individual operating the high end microscopes requires to have a interdisciplinary knowledge to study the characterization of biological molecules at a nanoscale. The complexity of cryo-electron microscopes makes the shortage of skilled professionals a key challenge to their use and adoption.
By Technology, single particle analysis segment of cryo-electron microscopy market, accounted for the largest share in 2021.
Based on technology, the global market is segmented into electron crystallography, single particle analysis, cryo-electron tomography, and other technologies. In 2021, single particle analysis segment accounted for the largest share of market. Rising use of technogical advanced instruments neurodegenerative research, rapid freezing of the samples, and requirement of small amount of purified sample is driving the growth of this segment.
By product & service, instruments segment of cryo-electron microscopy market, accounted for the largest share in 2021
Based on product & services, the global market is segmented into instruments, software, and services. The instruments segment is further segmented into fully automated instruments and semi-automated instruments. In 2021, fully automated instruments accounted for the largest share of market. The highest share of this segment is attributed to the technological advancements and new product launches in the segment.
By application, life science research & academia segment of cryo-electron microscopy market, to register significant growth in near future
Based on application, the global market is segmented into life science research & academia, pharma & biotech manufacturing, healthcare/medical applications, material analysis, and nanotechnology. Life science research & academia to register the highest growth rate during the forecast period. The major factors responsible for the highest growth rate of this segment are numerous fundings to promote research and development in structural biology and rising assistance by the major players in the market by providing different grants for cryo-EM installation.
By Region, North America is expected to be the largest region of cryo-electron microscopy market, during the forecast period
North America, comprising the US and Canada, accounted for the largest share of market market in 2021. Factors such as increase in the funding to support research activities, rise in the number of clinical trials, and growing applications in healthcare/medical sector are driving the growth of the of market in North America.
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As of 2021, prominent players in the market are Thermo Fisher Scientific (US), Danaher (US), JEOL Ltd. (Japan), Intertek Group Plc (UK), Charles River Laboratories (US).
Cryo-electron Microscopy Market Report Scope:
|
Report Metric |
Details |
|
Market size available for years |
2020–2028 |
|
Base year considered |
2021 |
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Forecast period |
2022–2028 |
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Forecast units |
Value (USD) |
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Segments covered |
Product & Service, Technology, Voltage, Application, and Region |
|
Geographies covered |
North America, Europe, Asia Pacific, Latin America, and Middle East and Africa |
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Companies covered |
Thermo Fisher Scientific (US), Danaher (US), JEOL (Japan), Intertek Group Plc (UK), Charles River Laboratories (US), Hitachi High-Technologies Corporation (Japan), Carl Zeiss (Germany), Gatan, Inc. (US), Oxford Instruments (UK) among others. |
This report has segmented the global cryo-electron microscopy market into following segments & sub-segments:
By Product & Service
- Instruments
- Fully Automated Instruments
- Semi-automated Instruments
- Software
- Services
By Technology
- Electron Crystallography
- Single Particle Analysis
- Cryo-electron Tomography
- Other Technologies
By Voltage
- 300 kV
- 200 kV
- 120 kV
By Application
- Life Science Research & Academia
- Cancer Research
- Omics Research
- Pharma & Biotech Manufacturing
- Cell & Gene Therapy
- Vaccines
- Preclinical & Clinical Research
- Healthcare/Medical Applications
- Disease Diagnosis & Pathology
- Toxicology Studies
- Material Analysis
- Nanotechnology
- Other Applications
By Region
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North America
- US
- Canada
-
Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
-
Asia Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest of Asia Pacific
- Latin America
- Middle East & Africa
Recent Developments
- In 2022, Thermo Fisher Scientific (US) launched the Glacios 2 Cryo-Transmission Electron Microscope (Cryo-TEM). The product features high-resolution capabilities and helps in drug discovery research.
- In 2022, Leica Microsystems (US), a subsidiary of Danaher launched a new Coral Cryo-electron workflow solution to support researchers with high-precision confocal 3D targeting
- In 2021, JEOL Ltd. (Japan) launched CRYO ARM 300 II. It is a cold emission cryo-electron microscope. It aims to enable the observation of biological specimens under high resolution
Frequently Asked Questions (FAQ):
What is the projected market value of the global cryo-electron microscopy market?
The global market of cryo-electron microscopy is projected to reach USD 2.1 billion.
What is the estimated growth rate (CAGR) of the global cryo-electron microscopy market for the next five years?
The global cryo-electron microscopy market is projected to grow at a Compound Annual Growth Rate (CAGR) of 11.6% from 2022 to 2028.
What are the major revenue pockets in the cryo-electron microscopy market currently?
North America, comprising the US and Canada, accounted for the largest share of market market in 2021. Factors such as increase in the funding to support research activities, rise in the number of clinical trials, and growing applications in healthcare/medical sector are driving the growth of the of cryo-electron microscopy market in North America.
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This study involved the extensive use of both primary and secondary sources. The research process involved the study of various factors affecting the industry to identify the segmentation types, industry trends, key players, competitive landscape, key market dynamics, and key player strategies.
Secondary Research
The secondary research process involves the widespread use of secondary sources, directories, databases (such as Bloomberg Businessweek, Factiva, and D&B Hoovers), white papers, annual reports, company house documents, investor presentations, and SEC filings of companies. Secondary research was used to identify and collect information useful for the extensive, technical, market-oriented, and commercial study of the cryo-electron microscopy market. It was also used to obtain important information about the key players and market classification & segmentation according to industry trends to the bottom-most level, and key developments related to market and technology perspectives. A database of the key industry leaders was also prepared using secondary research.
Primary Research
In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side include industry experts such as CEOs, vice presidents, marketing and sales directors, technology & innovation directors, and related key executives from various key companies and organizations in cryo-electron microscopy market. The primary sources from the demand side include medical OEMs, Oncologists, CDMOs and service providers, among others. Primary research was conducted to validate the market segmentation, identify key players in the market, and gather insights on key industry trends & key market dynamics.
A breakdown of the primary respondents is provided below:
*Others include sales managers, marketing managers, business development managers, product managers, distributors, and suppliers.
Note: Companies are classified into tiers based on their total revenue. As of 2021, Tier 1 = >USD 1,000 million, Tier 2 = USD 500–1,000 million, and Tier 3 = <USD 500 million.
To know about the assumptions considered for the study, download the pdf brochure
Market Estimation Methodology
In this report, the cryo-electron microscopy market's size was arrived at by using the revenue share analysis of leading players. For this purpose, key players in the market were identified, and their revenues from the market business were determined through various insights gathered during the primary and secondary research phases. Secondary research included the study of the annual and financial reports of the top market players. In contrast, primary research included extensive interviews with key opinion leaders, such as CEOs, directors, and key marketing executives.
To calculate the global market value, segmental revenues were calculated based on the revenue mapping of major solution/service providers. This process involved the following steps:
- Generating a list of major global players operating in the market.
- Mapping annual revenues generated by major global players from the product segment (or nearest reported business unit/product category)
- Revenue mapping of major players to cover major share of the global market share, as of 2021
- Extrapolating the global value of the market industry
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Data Triangulation
After arriving at the overall market size from the market size estimation process explained above, the global market was split into segments and subsegments. Data triangulation and market breakdown procedures were employed to complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments. The data was triangulated by studying various factors and trends from both the demand and supply sides. Additionally, the market was validated using both top-down and bottom-up approaches.
Objectives of the Study
- To define, describe, and forecast cryo-electron microscopy market on the basis of product & service, technology, application, and region
- To provide detailed information regarding the major factors influencing the growth potential of the global market (drivers, restraints, opportunities, challenges, and trends)
- To analyze the micro markets with respect to individual growth trends, future prospects, and contributions to the global market.
- To analyze key growth opportunities in the global market for key stakeholders and provide details of the competitive landscape for market leaders
- To forecast the size of market segments and/or subsegments with respect to five major regions, namely, North America (US and Canada), Europe (Germany, France, the UK, Italy, Spain, and the RoE), Asia Pacific (Japan, China, India, Australia, South Korea and the RoAPAC), Latin America, and the Middle East & Africa
- To profile the key players in the market and comprehensively analyze their market shares and core competencies
- To track and analyze the competitive developments undertaken in the global cryo-electron microscopy market, such as product launches; agreements; expansions; and mergers & acquisitions
Available Customizations
With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for the present global cryo-electron microscopy market report:
Product Analysis
- Product matrix, which gives a detailed comparison of the product portfolios of the top five companies
Company Information
- Detailed analysis and profiling of additional market players (up to 5)
Geographic Analysis
- Further breakdown of the Rest of Europe market into Russia, Belgium, the Netherlands, Switzerland, Austria, Finland, Sweden, Poland, and Portugal among other
- Further breakdown of the Rest of Asia Pacific market into Singapore, Taiwan, New Zealand, Philippines, Malaysia, and other APAC countries
- Further breakdown of the Latin American market into Brazil, Mexico, Colombia, Chile, Argentina, and Peru, among other
Generating Response ...
Growth opportunities and latent adjacency in Cryo-electron Microscopy Market