Endoscopic Submucosal Dissection Market by Product (Grasp, Clips, Gastroscopes, Colonoscopes), Indication (Cancer (Esophageal, Stomach, Colon), End User (Hospitals, Ambulatory Surgical Centers, Specialty Clinics) & Region - Global Forecasts to 2027
Updated on : Aug 22, 2024
The global endoscopic submucosal dissection market in terms of revenue was estimated to be worth $347 million in 2022 and is poised to reach $483 million by 2027, growing at a CAGR of 6.9% from 2022 to 2027. The rising incidence of target diseases such as cancer is expected to accelerate the need for endoscopic procedures, which, in turn, will propel the growth of this market in the coming years. Due to the high capital, training, and maintenance costs, endoscopic submucosal dissection procedures are generally expensive. Also, in most Asian countries, there is limited or no reimbursement for endoscopic submucosal dissection procedures from governments, which is expected to restrain market growth to a certain extent in the coming years.
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Endoscopic Submucosal Dissection Market Dynamics
Driver: Growing geriatric population
Rising age-related diseases, such as gastric cancer and gastrointestinal (GI) bleeding, are driving demand for endoscopic submucosal dissection (ESD). The aging population is more prone to these diseases, due to its weakened immune system and decreased physical activity. The number of people aged 65 and over is expected to reach 1.5 billion by 2050, which will fuel the demand for endoscopic submucosal dissection. The rising prevalence of cancer is also contributing to the growth of the endoscopic submucosal dissection market.
Restraint: High overhead cost of ESD procedures with limited reimbursements
The high overhead cost of ESD procedures with limited reimbursements is a major restraint to the growth of the endoscopic submucosal dissection market. This is because endoscopic submucosal dissection is a complex and time-consuming procedure and the costs associated with it are quite high. This makes the procedure unaffordable for many patients. Additionally, the reimbursement levels for endoscopic submucosal dissection are quite low, which is another major factor preventing its adoption. This factor is particularly prominent in developing countries where the healthcare infrastructure is not well-developed.
Opportunity: Expected increase in adoption of and preference for endoscopic submucosal dissection procedures in developing countries
The rise of endoscopic submucosal dissection (ESD) procedures in developing countries is expected to drive the growth of the global endoscopic submucosal dissection market. This is due to the increasing affordability of endoscopy procedures and the availability of cost-effective equipment in these markets. Additionally, the growing awareness of ESD procedures and the availability of skilled personnel in these countries are expected to further drive the market growth.
The rising prevalence of gastrointestinal disorders, such as esophageal and gastric cancer, is likely to propel the demand for ESD procedures in developing nations. Increased government focus on healthcare infrastructure and improvements in healthcare access, such as the implementation of universal healthcare systems, are expected to further drive the growth of the market. Additionally, the increasing focus of medical device manufacturers on expanding their presence in these markets is likely to provide a major boost to the market growth.
Furthermore, the growing number of mergers and acquisitions, strategic collaborations, and product launches by market players is expected to create lucrative opportunities for the growth of the global endoscopic submucosal dissection market.
Challenges: Risk of post-operative infection
Endoscopic submucosal dissection is a relatively new procedure used for the treatment of early gastrointestinal cancers, regardless of lesion size and configuration. It has gradually acquired popularity because of its minimally invasive nature. As compared to conventional endoscopic resection, endoscopic submucosal dissection is a more complex procedure and requires a higher level of technical skill. Therefore, it is associated with a higher complication rate. Post-operative fever is one of the most common complications. During ESD, the injection needle catheter is passed through the contaminated endoscopic channel and may directly inoculate bacteria into the bloodstream during the submucosal injection. In addition, ESD can produce mucosal defects. Bacteremia and/or endotoxemia can occur when submucosal and muscularis propria cells are exposed to native bacterial flora in the gastrointestinal tract. Bacteremia could be caused by the bacterial translocation of endogenous microbial flora through the injured mucosa into the bloodstream during the endoscopy procedure. These infectious complications have been reported to be infrequent and transient in both EMR and ESD of the stomach and colon.
Based on product, the knives segment will grow at the highest CAGR in the endoscopic submucosal dissection market during the forecast period.
Based on product, the market is segmented into knives, tissue retractors, graspers/clips, injection agents, gastroscopes and colonoscopes, and other products. The knives segment will continue to dominate the market in 2027, growing at the highest CAGR during the forecast period. In endoscopic submucosal dissection, lesions are circumscribed with a knife to free the lesion completely from the rest of the normal mucosa. There are a variety of knives available in the market, and the field has evolved rapidly over the past two decades with efforts to improve efficacy, safety, and cost-effectiveness.
Based on indications, the esophageal cancer segment will grow at the highest CAGR in the endoscopic submucosal dissection market during the forecast period.
Based on indication, the market is segmented into stomach cancer, colon cancer, and esophageal cancer. The esophageal cancer segment will grow at the highest CAGR during the forecast period. The incidence of superficial esophageal cancer (SEC) is increasing, particularly in Asian countries, including Japan, where screening for upper digestive tract cancers is common.
Based on end user, the hospitals segment will grow at the highest CAGR in the endoscopic submucosal dissection market during the forecast period.
In 2021, the hospitals segment will grow at the highest CAGR during the forecast period. Investments and incentives received by hospitals from government bodies are few key factors for the growth of this segment.
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North America is expected to account for the largest share of the endoscopic submucosal dissection market in 2021.
North America is expected to account for the largest share, and its dominance in the global market is mainly attributed to the high healthcare spending in the country, favourable reimbursement policies for endoscopic procedures, an increased incidence of cancer, constant research on endoscopy techniques, and a high number of FDA approvals for endoscopy systems in the US.
The prominent players in the endoscopic submucosal dissection market are Olympus Corporation (Japan), Boston Scientific Corporation (US), FUJIFILM Holdings Corporation (Japan), Sumitomo Bakelite Co., Ltd. (Japan), Creo Medical (UK), Medtronic (Ireland), MTW Endoskopie Manufaktur (Germany), HOYA Corporation (Japan), Ovesco Endoscope AG (Germany), Zeon Medical Inc. (Japan), KARL STORZ SE & Co. KG (Germany), ConMed Corporation (US), Micro-tech Endoscopy (China), Cook Group (US), Steris PLC (Ireland), Leo Medical Co., Ltd. (China), Erbe Elektromedizin GmbH (Germany), Taewoong Medical (South Korea), DCC Healthcare (Ireland), Kossen Co., Ltd. (South Korea), Innova Medica SPA (Italy), Jiangsu Vedkang Medical Science and Technology Co., Ltd. (China), Hangzhou AGS MedTech Co., Ltd. (China), and Beijing ZKSK Technology Co., Ltd. (China).
Endoscopic Submucosal Dissection Market Report Scope
Report Metric |
Details |
Market Revenue in 2022 |
$347 million |
Estimated Value by 2027 |
$483 million |
Growth Rate |
poised to grow at a CAGR of 6.9% |
Market Segmentation |
Product, Indication, End User & Region |
Market Drivers |
|
Market Opportunities |
|
Geographies covered |
North America, Europe, APAC, MEA, and Latin America |
This report categorizes the global endoscopic submucosal dissection market into the following segments and subsegments:
By Product
- Gastroscopes And Colonoscopes
- Knives
- Injection Agents
- Tissue Retractors
- Graspers/Clips
- Other Products
By Indication
- Stomach Cancer
- Colon Cancer
- Esophageal Cancer
By End User
- Hospitals
- Specialty Clinics
- Ambulatory Surgical Centers
- Other End Users
By Region
-
North America
- US
- Canada
-
Europe
- Germany
- France
- UK
- Italy
- Spain
- Rest of Europe
-
Asia Pacific
- Japan
- China
- India
- Rest of Asia Pacific
- Latin America
- Middle East and Africa
Recent Developments
In recent years, Endoscopic Submucosal Dissection (ESD) has become increasingly popular as a therapeutic option for resecting early gastric cancers. ESD is a minimally invasive endoscopic procedure that uses a special knife and suction device to cut and remove cancerous or precancerous tissue from the gastrointestinal tract. It is a safe, effective, and highly precise method of removing tumors from the stomach, esophagus, and rectum without the need for major surgery. Compared to other therapies such as endoscopic mucosal resection, ESD is more accurate and results in less bleeding and shorter recovery times. It has also been shown to be effective in treating early gastric cancer, reducing gastric cancer mortality rates. In addition, it has been used to treat early colorectal cancer, benign lesions, and dysplasia with high success rates. With its increasing use, ESD is revolutionizing the treatment of early gastric and colorectal cancers and other gastrointestinal diseases.
- In March 2021, FUJIFILM Holdings Corporation (Japan) acquired Diagnostic Imaging-related Business (the Business), Hitachi, Ltd.. This acquisition helped in the expansion of the medical systems business of FUJIFILM Corporation.
- In January 2021, Olympus Corporation (Japan) acquired Quest Innovations B.V. (Netherlands). The acquisition enabled Olympus to strengthen its surgical endoscopy capabilities and incorporate Quest’s advanced FIS capabilities into its comprehensive medical imaging portfolio.
- In November 2020, Creo Medical Group PLC (UK) acquired Boucart Medical SRL (Belgium). Creo Medical Group completed the acquisition of Boucart Medical SRL, the largest independent supplier of gastrointestinal endoscopy consumables in Belgium and Luxembourg.
Frequently Asked Questions (FAQs):
What is the projected market value of the global endoscopic submucosal dissection market?
The global market of endoscopic submucosal dissection is projected to reach USD 483 million.
What is the estimated growth rate (CAGR) of the global endoscopic submucosal dissection market for the next five years?
The global endoscopic submucosal dissection market is projected to grow at a Compound Annual Growth Rate (CAGR) of 6.9% from 2022 to 2027.
What are the major revenue pockets in the endoscopic submucosal dissection market currently?
North America is expected to account for the largest share, and its dominance in the global market is mainly attributed to the high healthcare spending in the country, favourable reimbursement policies for endoscopic procedures, an increased incidence of cancer, constant research on endoscopy techniques, and a high number of FDA approvals for endoscopy systems in the US.
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This study involved the extensive use of both primary and secondary sources. The research process involved the study of various factors affecting the industry to identify the segmentation types, industry trends, key players, competitive landscape, key market dynamics, and key player strategies.
Secondary Research
This research study involved the usage of comprehensive secondary sources; directories; databases such as Bloomberg Business, Factiva, and Dun & Bradstreet; white papers; annual reports; company house documents; investor presentations; and SEC filings of companies. Secondary research was used to identify and collect information useful for an extensive, technical, market-oriented, and commercial study of the endoscopic submucosal dissection market. It was also used to obtain important information about the key players, market classification and segmentation according to industry trends to the bottommost level, and key developments related to market and technology perspectives. A database of the key industry leaders was also prepared using secondary research.
Primary Research
In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. The primary sources from the supply side and demand side are detailed below.
A breakdown of the primary respondents is provided below:
Breakdown of Primary Interviews: Supply-Side Participants- by Company Type, Designation, and Region
Note 1: C-level primaries include CEOs, COOs, CTOs, and VPs.
Note 2: Other primaries include sales managers, marketing managers, and product managers.
Note 3: Companies are classified into tiers based on their total revenue. As of 2020: Tier 1 = >USD 1 billion, Tier 2 = USD 500 million to USD 1 billion, and Tier 3 = <USD 500 million.
To know about the assumptions considered for the study, download the pdf brochure
Breakdown of Primary Interviews: Demand-Side Participants by End-User, Designation, and Region
Note: Others include department heads, research scientists, and professors.
Market Size Estimation
The total size of the endoscopic submucosal dissection market was arrived at after data triangulation from three different approaches, as mentioned below. After each approach, the weighted average of all approaches was taken based on the level of assumptions used in each approach.
Data Triangulation
After arriving at the market size, the total market was divided into several segments and sub-segments. To complete the overall market engineering process and arrive at the exact statistics for all segments and sub-segments, data triangulation and market breakdown procedures were employed, wherever applicable. The following figure shows the market validation, source structure, and data triangulation methodology implemented in this report’s market engineering process.
Objectives of the Study
- To describe, analyze, and forecast the endoscopic submucosal dissection market by product, indication, end user, and region
- To describe and forecast the endoscopic submucosal dissection market for key regions, namely, North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa
- To provide detailed information regarding the drivers, restraints, opportunities, and challenges influencing the growth of the endoscopic submucosal dissection market
- To strategically analyze the ecosystem, regulations, patenting trend, value chain, Porter’s five forces, and prices pertaining to the market under study
- To strategically analyze micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
- To analyze market opportunities for stakeholders and provide details of the competitive landscape for market players
- To profile key players and comprehensively analyze their market shares and core competencies in the endoscopic submucosal dissection market
- To analyze competitive developments such as collaborations, acquisitions, product launches, expansions, and R&D activities in the endoscopic submucosal dissection market
Available customizations
With the given market data, MarketsandMarkets offers customizations as per your company’s specific needs. The following customization options are available for the report:
Company Information
- Detailed analysis and profiling of additional market players (up to 5)
Geographic Analysis
- Further breakdown of the RoE endoscopic submucosal dissection market into Austria, Finland, and others
- Further breakdown of the Latin America endoscopic submucosal dissection market into Brazil, Mexico, Argentina, Colombia, Chile, and others
Competitive Landscape Assessment
Market share analysis for the North America and Europe region, which provides market shares of the top 3–5 key players in the endoscopic submucosal dissection market
- Competitive leadership mapping for established players in the US
Key areas which can be focused in the ESD endoscopy market by a CEO in the Business Strategy
Market analysis: The CEO would need to analyze the market to understand the size, growth rate, and competitive landscape. This would involve identifying key trends and drivers in the market, as well as potential opportunities and threats.
Product development: The CEO would need to consider the company's product portfolio and identify areas for potential expansion or improvement. This might involve developing new products or features that meet the needs of customers or address unmet needs in the market.
Sales and marketing: The CEO would need to develop a sales and marketing strategy to drive growth and increase market share. This might involve investing in advertising, attending trade shows, or partnering with other companies to reach new customers.
Partnerships and collaborations: The CEO might also consider partnering with other companies to expand the company's capabilities or enter new markets. For example, the company might partner with a medical device manufacturer to develop new products or with a healthcare provider to expand distribution channels.
Some recent examples of growth strategies in the ESD endoscopy market include
Product innovation: Companies such as Olympus, Pentax Medical, and Fujifilm have introduced new products that offer advanced features such as high-definition imaging, advanced visualization, and artificial intelligence (AI) capabilities.
Mergers and acquisitions: In 2020, Boston Scientific acquired the majority stake in Preventice Solutions, a provider of remote monitoring and diagnostics for cardiac arrhythmias. This acquisition expanded Boston Scientific's capabilities in digital health and remote patient monitoring, which could be leveraged in the ESD endoscopy market.
Partnerships and collaborations: In 2019, Cook Medical and Taewoong Medical formed a strategic partnership to expand their product portfolios and market presence in the ESD endoscopy market. The partnership leveraged Cook Medical's expertise in endoscopic devices and Taewoong Medical's expertise in stents and other medical devices.
Top use cases including existing and futuristic for ESD endoscopy market
- Early detection and diagnosis of gastrointestinal cancers
- Treatment of early-stage gastrointestinal cancers
- Removal of precancerous polyps
- Endoscopic resection of gastrointestinal tumors
- Management of gastrointestinal bleeding
- Treatment of esophageal strictures
- Treatment of achalasia
- Removal of foreign bodies from the gastrointestinal tract
- Treatment of inflammatory bowel disease
- Endoscopic sleeve gastroplasty for weight loss
- Endoscopic treatment of gastroesophageal reflux disease (GERD)
- Endoscopic retrograde cholangiopancreatography (ERCP) for the treatment of biliary and pancreatic disorders
- Endoscopic ultrasound for the diagnosis and staging of gastrointestinal cancers
- Endoscopic mucosal resection (EMR) for the removal of benign and early-stage malignant tumors
- Endoscopic submucosal tunneling for the treatment of submucosal tumors
- Endoscopic dilation for the treatment of gastrointestinal strictures
- Endoscopic injection of botulinum toxin for the treatment of achalasia
- Endoscopic placement of stents for the treatment of gastrointestinal strictures and obstructions
- Endoscopic hemostasis for the treatment of gastrointestinal bleeding
- Endoscopic band ligation for the treatment of esophageal varices
- Endoscopic submucosal dissection (ESD) for the removal of early-stage gastrointestinal cancers
- Endoscopic mucosal ablation for the treatment of Barrett's esophagus
- Endoscopic radiofrequency ablation for the treatment of Barrett's esophagus and early-stage esophageal cancers
- Endoscopic cryotherapy for the treatment of early-stage esophageal cancers
- Endoscopic full-thickness resection for the removal of gastrointestinal tumors
- Endoscopic submucosal tunneling with endoscopic closure for the treatment of gastrointestinal perforations
- Endoscopic suturing for the closure of gastrointestinal perforations and leaks
- Endoscopic ultrasound-guided ablation for the treatment of pancreatic and biliary tumors
- Endoscopic ultrasound-guided drainage for the treatment of pancreatic pseudocysts and abscesses
- Endoscopic ultrasound-guided gastrojejunostomy for the treatment of gastric outlet obstruction
- Endoscopic ultrasound-guided portal pressure measurement for the diagnosis of portal hypertension
- Endoscopic mucosal resection with cap-assisted aspiration for the removal of large colorectal polyps
- Endoscopic ultrasound-guided fine needle aspiration for the diagnosis of pancreatic and biliary tumors
- Endoscopic ultrasound-guided fiducial marker placement for the delivery of stereotactic radiotherapy
- Endoscopic submucosal dissection with en bloc retrieval for the diagnosis of submucosal tumors
- Endoscopic removal of intraluminal cysts
- Endoscopic treatment of esophageal diverticula
- Endoscopic treatment of Zenker's diverticulum
- Endoscopic mucosal resection with underwater endoscopic mucosal resection for the removal of rectal lesions
- Endoscopic ultrasound-guided gastroenterostomy for the treatment of malignant gastric outlet obstruction
- Endoscopic ultrasound-guided biliary drainage for the treatment of obstructive jaundice
- Endoscopic ultrasound-guided pancreatic duct drainage for the treatment of pancreatic duct obstruction
- Endoscopic ultrasound-guided hepaticogastrostomy for the treatment of bile duct obstruction
Niche threats/restraints for ESD Endoscopy Business in enterprise?
While the ESD (Endoscopic Submucosal Dissection) endoscopy market presents several growth opportunities, there are also some potential threats and restraints that could affect the business. Here are some of the niche threats and restraints for ESD endoscopy business in enterprise
- High cost of ESD procedures compared to conventional endoscopic procedures
- Limited availability of skilled endoscopists who can perform ESD procedures
- Potential complications associated with ESD procedures, such as perforation, bleeding, and post-procedural stricture formation
- Lack of reimbursement coverage for ESD procedures in some regions
- Competition from alternative treatment options, such as laparoscopic or open surgical procedures
- Stringent regulatory requirements for ESD devices and procedures, which may limit product innovation and development
- Ethical and legal concerns around performing ESD procedures on elderly or high-risk patients
- Limited awareness among patients and healthcare providers about the benefits of ESD procedures, which may impact adoption rates
- Challenges in maintaining high-quality endoscopic imaging and visualization during ESD procedures, which may affect clinical outcomes
- Limited access to advanced endoscopic equipment and technologies in some regions, which may affect the ability to perform ESD procedures safely and effectively.
Recent examples of niche threats/restraints for ESD endoscopy business in enterprise
Lack of reimbursement coverage: In the United States, ESD procedures are not covered by Medicare, which is the largest health insurance provider in the country. This limits access to ESD procedures for many patients, and may also affect the profitability of ESD endoscopy businesses. However, some private insurance providers are starting to cover ESD procedures, which may help to improve access and reimbursement.
Regulatory requirements: In Japan, which is one of the largest markets for ESD endoscopy, regulatory requirements for ESD devices and procedures are becoming increasingly stringent. This has led to delays in device approvals and may also limit the ability of companies to innovate and develop new ESD technologies.
Competition from alternative treatment options: In some cases, laparoscopic or open surgical procedures may be a more effective or cost-efficient treatment option than ESD. This competition can limit the adoption of ESD procedures and may also impact the profitability of ESD endoscopy businesses.
Limited availability of skilled endoscopists: ESD procedures require a high level of technical skill and experience, which may limit the availability of skilled endoscopists who can perform these procedures. This can be a barrier to entry for new ESD endoscopy businesses, and may also limit the growth of existing businesses.
Ethical and legal concerns: In some cases, performing ESD procedures on elderly or high-risk patients may raise ethical and legal concerns around patient safety and informed consent. This can limit the adoption of ESD procedures and may also lead to negative publicity for ESD endoscopy businesses.
Growth opportunities and latent adjacency in Endoscopic Submucosal Dissection Market
what are the top 3 use cases of endoscopic submucosal dissection market in near future?