Hydrophobic Interaction Chromatography Market

Hydrophobic Interaction Chromatography Market by Product & Services (Resin, Columns (Empty, Prepacked), Buffer), Sample (Monoclonal Antibodies, Vaccines), End User (Pharmaceutical Companies, CROs & CMOs, Research Institutes) - Global Forecast to 2023

Report Code: BT 6542 Aug, 2018, by marketsandmarkets.com

[112 Pages Report] The global hydrophobic interaction chromatography market is projected to reach USD 418.2 million in 2023 from USD 271.0 million in 2017, at a CAGR of 7.5%. The base year considered for the study is 2017, and the forecast for the market size is provided for the period between 2018 and 2023. In the current market scenario, there is a growing demand for hydrophobic interaction chromatography. The major factors driving the growth of this market are the increasing demand for monoclonal antibodies and increasing R&D expenditure in biopharmaceuticals.

Market Dynamics

Drivers

  • Increasing demand for monoclonal antibodies
  • Increasing R&D expenditure in biopharmaceuticals

Opportunities

  • Increasing number of CMOs and CROs
  • Patent Expiry

Challenges

  • Lack of skilled professionals and highly qualified researchers

Monoclonal antibodies likely to drive the market

In the past decade, there has been a significant increase in the demand for mAbs not only in oncology but several other therapeutic areas such as Alzheimer’s, autoimmune diseases, and inflammatory disorders. These therapeutic areas have also gained prominence in recent years, as a result of which, almost all major pharmaceutical companies have undertaken R&D on therapeutic antibodies. In the purification of mAbs, impurities and aggregates are removed through different chromatography resins, including hydrophobic interaction chromatography resins. In drug discovery applications, hydrophobic interaction chromatography plays an important role in capturing and polishing target proteins during the purification process.

Hydrophobic interaction chromatography is widely used for mAbs purification. Therefore, the increase in the number of mAbs approvals will eventually drive the demand for hydrophobic interaction chromatography resins.

Objectives of the Study

  • To define, describe, and forecast the hydrophobic interaction chromatography market on the basis of product & service, sample type, end user, and region
  • To provide detailed information regarding the major factors influencing the growth of the market (drivers, opportunities, and industry-specific challenges)
  • To strategically analyze the micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
  • To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
  • To forecast the size of the market segments with respect to four major regional segments, namely, North America, Europe, Asia Pacific, and the Rest of the World (RoW)
  • To profile the key players in the market and comprehensively analyze their market positions and core competencies
  • To track and analyze competitive developments such as collaborations and acquisitions, product launches, and research and development activities in the hydrophobic interaction chromatography market

Research Methodology

Top-down and bottom-up approaches were used to validate the size of the global hydrophobic interaction chromatography market and estimate the size of various other dependent submarkets. Major players in the market were identified through secondary research, and their market presence was studied through primary and secondary research. Secondary research included Annual Reports, Press Releases, SEC Filings, Investor Presentations, World Health Organization, National Institutes of Health, National Center for Biotechnology Information, US FDA, Chromatographic Society, Chinese American Chromatography Association, European Society for Separation Science, American Association for Laboratory Accreditation, Research Institute for Chromatography, Chromatography Institute of America, Chromatographic Society of India, Journals, BioPharm Magazine, Expert Interviews, and MarketsandMarkets Analysis. Whereas, primary research included extensive interviews with key opinion leaders such as CEOs, directors, and marketing executives. The percentage splits, shares, and breakdowns of the segments were determined using secondary sources and verified through primary sources. This data is consolidated and added to detailed inputs and analysis from MarketsandMarkets and presented in this report.

Hydrophobic Interaction Chromatography Market

To know about the assumptions considered for the study, download the pdf brochure

The key players in the global hydrophobic interaction chromatography market are Bio-Rad Laboratories (US), Sartorius (Germany), and Thermo Fisher Scientific (US).

Target Audience:

  • Chromatography product manufacturers
  • Third-party chromatography suppliers
  • Environment protection agencies and institutes
  • Pharmaceutical and biotechnology companies
  • Contract manufacturing companies (CMOs)
  • Contract research organizations (CROs)
  • Market research and consulting firms
  • Regulatory bodies
  • Venture capitalists

Scope of the Report

The research report categorizes the global hydrophobic interaction chromatography market into the following segments and subsegments:

Hydrophobic Interaction Chromatography Market, by Product and Service

  • Products
    • Resins, by Type
      1. Bead-based Resins
      2. Membrane-based Resins
    • Columns, by Type
      1. Empty Columns
      2. Prepacked Columns
    • Columns, by Material
      1. Stainless Steel Columns
      2. Glass and Plastic Columns
    • Buffers
    • Other Products
  • Services

Hydrophobic Interaction Chromatography Market, by Sample Type

  • Monoclonal Antibodies
  • Vaccines
  • Other Samples

Hydrophobic Interaction Chromatography Market, by End User

  • Pharmaceutical & Biopharmaceutical Companies
  • CROs & CMOs
  • Research & Academic Institutes

Hydrophobic Interaction Chromatography Market, by Region

  • North America
    • US
    • Canada
  • Europe
  • Asia Pacific
  • Rest of the World (RoW)

Available customizations

With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for the report:

Geographical Analysis

  • Further breakdown of the European hydrophobic interaction chromatography market into Germany, France, the UK, Italy, and Spain
  • Further breakdown of the APAC hydrophobic interaction chromatography market into India, China, Japan, and Australia

Company Information

  • Detailed analysis and profiling of additional market players (up to 5)

The global hydrophobic interaction chromatography market is projected to reach USD 418.2 million in 2023 from USD 291.3 billion in 2018, at a CAGR of 7.5%. The increasing demand for monoclonal antibodies and increasing R&D expenditure in biopharmaceuticals are driving the growth of the market.

In this report, the market has been categorized based on product & service, sample type, end user, and region. The HIC products market includes resins, columns, buffers, and other HIC products. In 2018, HIC resins are expected to dominate the products market. This segment is also estimated to grow at the highest CAGR during the forecast period owing to the increasing demand for HIC resins for the purification of hydrophobic protein molecules.

On the basis of sample type, the global hydrophobic interaction chromatography market is divided into monoclonal antibodies, vaccines, and other samples. In 2018, the monoclonal antibodies segment is expected to account for the largest share of the global hydrophobic interaction chromatography market. This large share of this segment is attributed to increasing application of mAbs in autoimmune disorders, CVD, infectious diseases, and cancer.

In 2018, North America is expected to account for the largest share of the global hydrophobic interaction chromatography market. The availability of government and public funding for protein-based research projects, increased adoption of automated purification instruments, high demand for protein biologics, and increasing R&D efforts by pharmaceutical and biotechnology companies are some of the major factors driving the growth of the HIC market in North America.

Hydrophobic Interaction Chromatography Market

Increasing demand for membrane-based resins and the growing requirement of ready-to-use prepacked columns in purification processes are likely to drive the hydrophobic market

Resins

HIC resins are used for purifying biomolecules such as monoclonal antibodies, therapeutic enzymes, aggregates, hormones, viruses, vaccines, and endotoxins. Bead-based resins and membrane-based resins are the two types of HIC resins available in the market.

Bead based

Bead-based resins are the most commonly preferred resins by drug manufacturers as they offer high resolution and high surface area for the adsorption of proteins. These resins are available in porous and non-porous forms, and can be used with different buffer mixtures without altering the size of the beads

Membrane based

Membrane-based resins provide fast flow-rate purification of therapeutic proteins as compared to conventional bead-based resins. Membrane HIC helps to achieve increased throughput, saves amount of buffer solutions, and decreases raw material costs in the purification process. Also, these resins have a high binding capacity and reduce impurities to a large extent.

The key players in the global hydrophobic interaction chromatography market include GE Healthcare (US), Bio-Rad Laboratories (US), Sartorius (Germany), Thermo Fisher Scientific (US), and Tosoh Corporation (Japan). These players focus on both organic and inorganic growth strategies, such as product launches, collaborations, and acquisition to maintain and enhance their market share in the hydrophobic interaction chromatography market.

Hydrophobic interaction chromatography market is consolidated in nature with a major share attributed by top companies in this market such as GE Healthcare, Tosoh Corporation, Merck, and Bio-Rad. Rankings for this market have been derived on the basis of several aspects such as segmental revenue, market strategies, brand image, product portfolios, product innovation, and geographic presence.

To speak to our analyst for a discussion on the above findings, click Speak to Analyst

Table of Contents

1 Introduction (Page No. - 14)
    1.1 Objectives of the Study
    1.2 Market Definition
    1.3 Market Scope
           1.3.1 Markets Covered
           1.3.2 Years Considered for the Study
    1.4 Currency
    1.5 Limitations
    1.6 Stakeholders

2 Research Methodology (Page No. - 18)
    2.1 Market Size Estimation
    2.2 Market Breakdown and Data Triangulation
           2.2.1 Key Data From Secondary Sources
           2.2.2 Key Data From Primary Sources
                    2.2.2.1 Key Industry Insights

3 Executive Summary (Page No. - 25)

4 Premium Insights (Page No. - 29)
    4.1 Hydrophobic Interaction Chromatography (HIC) Market Overview
    4.2 Hydrophobic Interaction Chromatography Market, By Sample Type and Region (2018)
    4.3 Hydrophobic Interaction Chromatography Market, By Product, 2018 vs 2023
    4.4 Hydrophobic Interaction Chromatography Market, By End User, 2018–2023

5 Market Overview (Page No. - 33)
    5.1 Introduction
    5.2 Market Dynamics
           5.2.1 Drivers
                    5.2.1.1 Increasing Demand for Monoclonal Antibodies
                    5.2.1.2 Increasing R&D Expenditure in Biopharmaceuticals
           5.2.2 Opportunities
                    5.2.2.1 Increasing Number of Cmos and Cros
                    5.2.2.2 Patent Expiry
           5.2.3 Challenges
                    5.2.3.1 Lack of Skilled Professionals and Highly Qualified Researchers

6 Hydrophobic Interaction Chromatography Market, By Product and Service (Page No. - 37)
    6.1 Introduction
    6.2 Products
           6.2.1 Resins
                    6.2.1.1 Bead-Based Resins
                    6.2.1.2 Membrane-Based Resins
           6.2.2 Columns
                    6.2.2.1 Empty Columns
                    6.2.2.2 Prepacked Columns
           6.2.3 HIC Columns, By Material
                    6.2.3.1 Stainless Steel Columns
                    6.2.3.2 Glass & Plastic Columns
           6.2.4 Buffers
           6.2.5 Other Products
    6.3 Services

7 Hydrophobic Interaction Chromatography Market, By Sample Type (Page No. - 49)
    7.1 Introduction
    7.2 Monoclonal Antibodies
    7.3 Vaccines
    7.4 Other Samples

8 Hydrophobic Interaction Chromatography Market, By End User (Page No. - 53)
    8.1 Introduction
    8.2 Pharmaceutical & Biopharmaceutical Companies
    8.3 Contract Research Organizations & Contract Manufacturing Organizations
    8.4 Research & Academic Institutes

9 Hydrophobic Interaction Chromatography Market, By Region (Page No. - 58)
    9.1 Introduction
    9.2 North America
           9.2.1 US
           9.2.2 Canada
    9.3 Europe
    9.4 Asia Pacific
    9.5 Rest of the World

10 Competitive Landscape (Page No. - 82)
     10.1 Market Overview
     10.2 Market Ranking Analysis, 2018
     10.3 Competitive Situation and Trends
             10.3.1 Acquisitions
             10.3.2 Product Launches
             10.3.3 Collaborations, Agreements, and Partnerships
             10.3.4 Other Developments

11 Company Profiles (Page No. - 85)
(Introduction, Products & Services, Strategy, & Analyst Insights, Developments, MnM View)*
     11.1 Bio-Rad Laboratories
     11.2 Sartorius AG
     11.3 Thermo Fisher Scientific
     11.4 GE Healthcare
     11.5 Tosoh Corporation
     11.6 Waters Corporation
     11.7 Geno Technology
     11.8 Sepax Technologies
     11.9 JNC Corporation
     11.10 Knauer
     11.11 Merck KGaA
     11.12 Mitsubishi Chemical Corporation
     11.13 Danaher Corporation
     11.14 Avantor Performance Materials

*Details on Marketsandmarkets View, Introduction, Product & Services, Strategy, & Analyst Insights, New Developments Might Not Be Captured in Case of Unlisted Companies.

12 Appendix (Page No. - 107)
     12.1 Discussion Guide
     12.2 Knowledge Store: Marketsandmarkets’ Subscription Portal
     12.3 Available Customizations
     12.4 Related Reports
     12.5 Author Details


List of Tables (83 Tables)

Table 1 Recently Approved Monoclonal Antibodies in the US and EU
Table 2 Bestselling Biologics Expected to Go Off-Patent
Table 3 Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 4 Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 5 Hydrophobic Interaction Chromatography Products Market, By Region, 2016–2023 (USD Million)
Table 6 North America: Hydrophobic Interaction Chromatography Products Market, By Country, 2016–2023 (USD Million)
Table 7 Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 8 Hydrophobic Interaction Chromatography Resins Market, By Region, 2016–2023 (USD Million)
Table 9 North America: Hydrophobic Interaction Chromatography Resins Market, By Country, 2016–2023 (USD Million)
Table 10 Bead-Based Resins Market, By Region, 2016–2023 (USD Million)
Table 11 Membrane-Based Resins Market, By Region, 2016–2023 (USD Million)
Table 12 Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 13 Hydrophobic Interaction Chromatography Columns Market, By Region, 2016–2023 (USD Million)
Table 14 North America: Hydrophobic Interaction Chromatography Columns Market, By Country, 2016–2023 (USD Million)
Table 15 Empty Columns Market, By Region, 2016–2023 (USD Million)
Table 16 Prepacked Columns Market, By Region, 2016–2023 (USD Million)
Table 17 Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 18 Stainless Steel Columns Market, By Region, 2016–2023 (USD Million)
Table 19 Glass & Plastic Columns Market, By Region, 2016–2023 (USD Million)
Table 20 Hydrophobic Interaction Chromatography Buffers Market, By Region, 2016–2023 (USD Million)
Table 21 North America: Hydrophobic Interaction Chromatography Buffers Market, By Country, 2016–2023 (USD Million)
Table 22 Other Hydrophobic Interaction Chromatography Products Market, By Region, 2016–2023 (USD Million)
Table 23 Hydrophobic Interaction Chromatography Services Market, By Region, 2016–2023 (USD Million)
Table 24 North America: Hydrophobic Interaction Chromatography Services Market, By Country, 2016–2023 (USD Million)
Table 25 Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 26 Hydrophobic Interaction Chromatography Market for Monoclonal Antibodies, By Region, 2016–2023 (USD Million)
Table 27 Hydrophobic Interaction Chromatography Market for Vaccines, By Region, 2016–2023 (USD Million)
Table 28 Hydrophobic Interaction Chromatography Market for Other Samples, By Region, 2016–2023 (USD Million)
Table 29 Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 30 Hydrophobic Interaction Chromatography Market for Pharmaceutical and Biopharmaceutical Companies, By Region, 2016–2023 (USD Million)
Table 31 North America: Hydrophobic Interaction Chromatography Market for Pharmaceutical and Biopharmaceutical Companies, By Country, 2016–2023 (USD Million)
Table 32 Hydrophobic Interaction Chromatography Market for Contract Research Organizations & Contract Manufacturing Organizations, By Region, 2016–2023 (USD Million)
Table 33 North America: Hydrophobic Interaction Chromatography Market for Contract Research Organizations & Contract Manufacturing Organizations, By Country, 2016–2023 (USD Million)
Table 34 Hydrophobic Interaction Chromatography Market for Research & Academic Institutes, By Region, 2016–2023 (USD Million)
Table 35 North America: Hydrophobic Interaction Chromatography Market for Research & Academic Institutes, By Country, 2016–2023 (USD Million)
Table 36 Hydrophobic Interaction Chromatography Market, By Region, 2016–2023 (USD Million)
Table 37 North America: Hydrophobic Interaction Chromatography Market, By Country, 2016–2023 (USD Million)
Table 38 North America: Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 39 North America: Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 40 North America: Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 41 North America: Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 42 North America: Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 43 North America: Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 44 North America: Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 45 US: Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 46 US: Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 47 US: Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 48 US: Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 49 US: Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 50 US: Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 51 US: Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 52 Canada: Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 53 Canada: Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 54 Canada: Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 55 Canada: Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 56 Canada: Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 57 Canada: Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 58 Canada: Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 59 Europe: Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 60 Europe: Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 61 Europe: Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 62 Europe: Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 63 Europe: Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 64 Europe: Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 65 Europe: Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 66 Asia Pacific: Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 67 Asia Pacific: Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 68 Asia Pacific: Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 69 Asia Pacific: Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 70 Asia Pacific: Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 71 Asia Pacific: Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 72 Asia Pacific: Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 73 RoW: Hydrophobic Interaction Chromatography Market, By Product & Service, 2016–2023 (USD Million)
Table 74 RoW: Hydrophobic Interaction Chromatography Products Market, By Type, 2016–2023 (USD Million)
Table 75 RoW: Hydrophobic Interaction Chromatography Resins Market, By Type, 2016–2023 (USD Million)
Table 76 RoW: Hydrophobic Interaction Chromatography Columns Market, By Type, 2016–2023 (USD Million)
Table 77 RoW: Hydrophobic Interaction Chromatography Columns Market, By Material, 2016–2023 (USD Million)
Table 78 RoW: Hydrophobic Interaction Chromatography Market, By Sample Type, 2016–2023 (USD Million)
Table 79 RoW: Hydrophobic Interaction Chromatography Market, By End User, 2016–2023 (USD Million)
Table 80 Acquisitions, 2015-2018
Table 81 Product Launches, 2015-2018
Table 82 Collaborations 2015–2018
Table 83 Other Developments, 2015-2018


List of Figures (27 Figures)

Figure 1 Research Design: HIC Market
Figure 2 HIC Market: Top-Down Approach
Figure 3 HIC Market: Bottom-Up Approach
Figure 4 Breakdown of Primary Interviews: By Company Type, Designation, and Region
Figure 5 Data Triangulation Methodology
Figure 6 Hydrophobic Interaction Chromatography Market, By Product & Service, 2018 vs 2023
Figure 7 Hydrophobic Interaction Chromatography Products Market, By Type, 2018 vs 2023
Figure 8 Hydrophobic Interaction Chromatography Market, By Sample Type, 2018 vs 2023
Figure 9 Hydrophobic Interaction Chromatography Market, By End User, 2018 vs 2023
Figure 10 Geographical Snapshot of the Hydrophobic Interaction Chromatography Market
Figure 11 Increasing Demand for Monoclonal Antibodies and Growing R&D Expenditure in the Biopharmaceutical Industry—Key Drivers for the Market
Figure 12 Monoclonal Antibodies Segment to Account for the Largest Market Share in 2018
Figure 13 Resins Will Continue to Dominate the HIC Products & Services Market in 2023
Figure 14 Pharmaceutical & Biopharmaceutical Companies to Account for the Largest Share in 2018
Figure 15 Hydrophobic Interaction Chromatography Market: Drivers, Opportunities, & Challenges
Figure 16 Geographic Snapshot (2018): Asia Pacific to Be the Fastest-Growing Regional Market
Figure 17 North America: Hydrophobic Interaction Chromatography Market Snapshot
Figure 18 Asia Pacific: Hydrophobic Interaction Chromatography Market Snapshot
Figure 19 Rank of Companies in the Global Hydrophobic Interaction Chromatography Market, 2018
Figure 20 Bio-Rad Laboratories: Company Snapshot (2017)
Figure 21 Sartorius AG: Company Snapshot (2017)
Figure 22 Thermo Fisher Scientific: Company Snapshot (2017)
Figure 23 GE Healthcare: Company Snapshot (2017)
Figure 24 Tosoh Corporation: Company Snapshot (2017)
Figure 25 Water Corporation: Company Snapshot (2017)
Figure 26 Merck KGaA: Company Snapshot (2017)
Figure 27 Danaher Corporation: Company Snapshot (2017)


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