Label-Free Detection Market by Technology (Surface Plasmon Resonance, Bio-layer Interferometry), Products (Consumables, Microplates, Biosensor Chips), Applications (Binding Kinetics, Thermodynamics, Lead Generation), End User - Global Forecast to 2022
Label-free detection is gaining widespread acceptance as an important research and development tool in biotechnology and pharmaceutical industries as well as in academic research. It helps in the investigation of biomolecular interactions without using fluorescent labels, which usually cause spatial interference or quenching. The major advantage offered by label-free technology is that it can help in the study of varied cell types and targets. Label-free detection is a highly sensitive method used for the measurement of endogenous targets in live cell assays, without the use of dyes, labeling reagents, and engineered cells. Owing to this, label-free detection is used widely in basic research, drug discovery, and drug development. The global label-free detection market is expected to reach USD 1.31 Billion by 2022 from USD 0.87 Billion in 2017, at a CAGR of 8.5% during forecast period. Innovations in label-free detection technologies, increasing drug discovery programs through research partnerships between pharmaceutical companies and academic institutes, and growth in the global pharmaceutical and biotechnology industries are factors driving the growth of this market. The development of more sensitive label-free technologies and rising life science research activities in emerging markets are expected to provide a range of growth opportunities for players in the market
By product, instrument segment is expected to grow at the highest growth rate during the forecast period
The instrument segment is projected to register the highest growth rate during the forecast period. The drug discovery industry is adopting label-free technologies for various molecular and cellular assays. These technologies result in creating demand for automated, easy-to-use bioanalytical systems, which is driving the growth of this market. Additionally, with the help of enhanced instrumentation, pharmaceutical and biotechnology companies can streamline and simplify laboratory workflows to improve productivity that will lead to a reduction in costs.
By technology, bio-layer interferometry segment to record the highest CAGR during the forecast period
Bio-layer interferometry technology segment is projected to register a higher CAGR during the forecast period. It is a fast and high-throughput technology that allows real-time analysis for the determination of affinity, kinetics, and concentration. Bio-layer interferometry has gained major acceptance in the recent years owing to its ability to detect rapid real-time biomolecular interactions (for instance, protein-protein interactions) in micro-volume sample sizes.
By application type, binding kinetics segment to record the highest CAGR during the forecast period
Binding kinetics application segment is projected to register a higher CAGR during the forecast period. Factors such as increasing drug discovery research and development activities and increasing efforts to study biomolecular kinetics through label-free detection technologies are driving the growth of this segment.
By end user type, academic and research institutes segment to record the highest CAGR during the forecast period
Academic and research institutes end user segment is projected to register a higher CAGR during the forecast period. Label-free detection plays a vital role in the discovery of therapeutic agents and understanding protein biology studies such as protein-protein interactions. Growth in the academic and research institutes segment is primarily attributed to the growing research and development activities and development of cost-effective instruments.
North America to account for the largest market size during the forecast period.
North America is expected to account for the largest share of this market. Increasing research activities in drug discovery and development, growing number of biotechnology and pharmaceutical companies, and higher investments for label-free detection as compared to other regions are the key factors driving the growth of the label-free detection market in North America.
Driver: Innovations in label-free detection technologies
Technological innovations and advancements in label-free detection technologies, such as surface plasmon resonance (SPR), bio-layer interferometry (BLI), and quartz crystal microbalance (QCM), play a pivotal role in drug discovery. Surface plasmon resonance (SPR) helps in the accurate analysis of biomolecular interactions. It is one of the key label-free detection methods in which molecular interactions are analyzed on a surface. Another technological innovation is SPR imaging (SPRi), which improves the efficiency of SPR by facilitating the analysis of multiple biomolecular interactions simultaneously.
Similarly, bio-layer interferometry (BLI) is another technologically advanced label-free detection technology, which is used for biomolecular interaction analysis. BLI is used in a wide range of biomolecular interactions, including antibody-antigen, DNA-protein, protein-protein, metabolite-protein, enzyme-substrate/inhibitor, and small molecule-drug target interactions. Quartz crystal microbalance (QCM) has also had a major impact on the amplification and analysis of biomolecular interactions in drug discovery. This technology helps in the detection of large changes in molecular quantification with the help of sensors.
These innovative and advanced applications of label-free detection technologies have increased their adoption by pharmaceutical and biopharmaceutical companies for biomolecular analysis during drug discovery. This is, in turn, expected to drive market growth.
Opportunity: Rising life science research activities in emerging markets
Growth in the Asian economies, particularly China and India, along with increased investments in biotechnology and drug discovery are the major factors driving the label-free detection market in Asia. Currently, most Asian countries do not possess established business models but have the scientific talent to develop strong local biotechnology industries. Hence, the number of mergers, collaborations, and acquisitions are on the rise in the Asian continent. In 2015, mergers & acquisitions in China went up by 138% from 2014, generating USD 32 billion. Many Asian economies have modified regulations, policies, and guidelines to support investments, innovation, and commercialization. Owing to this, research activities in the life science industry are on the rise.
Many companies such as AstraZeneca, GlaxoSmithKline, Sanofi, and Johnson & Johnson have also announced plans for investing in the life science R&D activities in the emerging markets in the coming years. These increasing investments in the emerging markets will boost research and development activities, which in turn will provide a range of growth opportunities for players in the market.
Trend: Microscale thermophoresis
Microscale thermophoresis (MST) is a powerful new technology, which enables the quantitative analysis of molecular interactions at the microliter scale and with high sensitivity. It offers more superior features in determining the parameters of molecular interactions. The binding affinities of any pair of interacting molecules are determined quickly by fast measurement interactions between those molecules. The binding affinities are recorded in the time frame of minutes, with the binding partners in the solution.
Material consumption is minimal using this technology and experiments can be carried out with a broad range of solution conditions, including detergent mixtures and complex bioliquids. It is also temperature-controlled, cost-efficient, and fast as well as offers unmatched flexibility.
Scope of the Report
|
Report Metric |
Details |
|
Market Size Available for Years |
20152022 |
|
Base year considered |
2016 |
|
Forecast period |
20172022 |
|
Forecast units |
Million (USD) |
|
Segments covered |
Product, Technology, Application, End User and Region |
|
Geographies covered |
North America, Europe, Asia Pacific, Rest of the World (RoW) |
|
Companies covered |
General Electric, Danaher Corporation, Perkinelmer, Ametek, F. Hoffman-La Roche AG, Malvern Panalytical, TA Instruments, Corning Incorporated, Horiba, Shimadzu Corporation, Hitachi High-Technologies Corporation |
The research report categorizes the label-free detection market into the following segments and subsegments:
By Product
- Biosensor Chips
- Microplates
By Technology
- Surface Plasmon Resonance
- Bio-Layer Interferometry
- Isothermal Titration Calorimetry
- Differential Scanning Calorimetry
- Other Label-Free Detection Technologies
By Application
- Binding Kinetics
- Binding Thermodynamics
- Endogenous Receptor Detection
- Hit Confirmation
- Other Applications
- Lead Generation
- Other Applications
By End User
- Pharmaceutical & Biotechnology Companies
- Academic Research Institutes
- Contract Research Organizations
- Other End Users
By Region
- North America
- US
- Canada
- Europe
- Germany
- UK
- France
- Italy
- Spain
- Rest of Eupore (RoE)
- Asia Pacific
- Japan
- China
- India
- Rest of Asia (RoA)
- Rest of the World (RoW)
Key Market Players
General Electric Company, PerkinElmer, AMETEK, Corning Incorporated, Malvern PANalytical, TA Instruments, F. Hoffman-La Roche AG, Hitachi High-Technologies Corporation, HORIBA , Shimadzu Corporation, , Danaher Corporation, Mettler-Toledo International, BiOpti, Wyatt Technology Corporation.
Recent DevelopmentsProduct Launches
Critical questions the report answers:
- Where will all these developments take the industry in the long term?
- What are the upcoming trends for the label-free detection market?
- Which segment provides the most opportunity for growth?
- Who are the leading vendors operating in this market?
- What are the opportunities for new market entrants?
To speak to our analyst for a discussion on the above findings, click Speak to Analyst
Table of Contents
1 Introduction (Page No. - 16)
1.1 Objectives of the Study
1.2 Market Definition
1.3 Market Scope
1.3.1 Market Covered
1.3.2 Years Considered for the Study
1.4 Currency
1.5 Limitations
1.6 Stakeholders
2 Research Methodology (Page No. - 19)
2.1 Research Data
2.1.1 Secondary Data
2.1.1.1 Key Data From Secondary Sources
2.1.2 Primary Data
2.1.2.1 Key Data From Primary Sources
2.1.2.2 Breakdown of Primary Interviews: By Company Type, Designation, and Region
2.2 Market Size Estimation
2.2.1 Bottom-Up Approach
2.2.2 Top-Down Approach
2.3 Market Breakdown & Data Triangulation
2.4 Assumptions for the Study
3 Executive Summary (Page No. - 27)
4 Premium Insights (Page No. - 31)
4.1 Label-Free Detection Market: Overview
4.2 Asia Pacific Market, By Country & Technology (2017)
4.3 Global Market, By Product, 20172022
4.4 Geographical Snapshot of the Global Market
5 Market Overview (Page No. - 34)
5.1 Introduction
5.2 Market Dynamics
5.2.1 Drivers
5.2.1.1 Innovations in Label-Free Detection Technologies
5.2.1.2 Increasing Drug Discovery Programs Through Research Partnerships Between Pharmaceutical Companies and Academic Institutes
5.2.1.3 Growth in the Global Pharmaceutical and Biotechnology Industries
5.2.1.3.1 Significant Expenditure on Research and Development By Biopharma Companies
5.2.1.3.2 Rising Pharmaceutical Outsourcing
5.2.2 Restraints
5.2.2.1 High Cost of Instruments
5.2.3 Opportunities
5.2.3.1 Development of More Sensitive Label-Free Technologies
5.2.3.2 Rising Life Science Research Activities in Emerging Markets
5.2.4 Challenges
5.2.4.1 Shortage of Skilled Professionals
5.2.4.2 Unclear Fda Guidelines
5.2.5 Technology Trends
5.2.5.1 Microscale Thermophoresis
6 Label-Free Detection Market, By Product (Page No. - 39)
6.1 Introduction
6.2 Instruments
6.3 Consumables
6.3.1 Biosensor Chips
6.3.2 Microplates
7 Label-Free Detection Market, By Technology (Page No. - 45)
7.1 Introduction
7.2 Surface Plasmon Resonance
7.3 Bio-Layer Interferometry
7.4 Isothermal Titration Calorimetry
7.5 Differential Scanning Calorimetry
7.6 Other Lfd Technologies
8 Label-Free Detection Market, By Application (Page No. - 52)
8.1 Introduction
8.2 Binding Kinetics
8.3 Binding Thermodynamics
8.4 Endogenous Receptor Detection
8.5 Hit Confirmation
8.6 Lead Generation
8.7 Other Applications
9 Label-Free Detection Market, By End User (Page No. - 59)
9.1 Introduction
9.2 Pharmaceutical & Biotechnology Companies
9.3 Academic & Research Institutes
9.4 Contract Research Organizations
9.5 Other End Users
10 Label-Free Detection Market, By Region (Page No. - 65)
10.1 Introduction
10.2 North America
10.2.1 US
10.2.2 Canada
10.3 Europe
10.3.1 Germany
10.3.2 UK
10.3.3 France
10.3.4 Italy
10.3.5 Spain
10.3.6 Rest of Europe (RoE)
10.4 Asia Pacific
10.4.1 China
10.4.2 Japan
10.4.3 India
10.4.4 Rest of Asia Pacific (RoAPAC)
10.5 Rest of the World (RoW)
11 Competitive Landscape (Page No. - 114)
11.1 Market Share Analysis
12 Company Profile (Page No. - 115)
(Overview, Products Offered, Product Offering Scorecard, Business Strategy Scorecard, Recent Developments)*
12.1 General Electric
12.2 Danaher Corporation
12.3 Perkinelmer
12.4 Ametek
12.5 F. Hoffman-La Roche AG
12.6 Malvern Panalytical
12.7 TA Instruments
12.8 Corning Incorporated
12.9 Horiba
12.10 Shimadzu Corporation
12.11 Hitachi High-Technologies Corporation
*Details on Marketsandmarkets View, Overview, Products Offered, Product Offering Scorecard, Business Strategy Scorecard, and Recent Developments Might Not Be Captured in Case of Unlisted Companies.
13 Appendix (Page No. - 139)
13.1 Industry Insights
13.2 Discussion Guide
13.3 Knowledge Store: Marketsandmarkets Subscription Portal
13.4 Introducing RT: Real-Time Market Intelligence
13.5 Available Customizations
13.6 Related Reports
13.7 Author Details
List of Tables (110 Tables)
Table 1 R&D Expenditure of Pharmaceutical Companies in 2015
Table 2 Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 3 Label-Free Detection Instruments Market, By Region, 20152022 (USD Million)
Table 4 Label-Free Detection Consumables Market, By Region, 20152022 (USD Million)
Table 5 Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 6 Label-Free Detection Consumables Market for Biosensor Chips, By Region, 20152022 (USD Million)
Table 7 Label-Free Detection Consumables Market for Microplates, By Region, 20152022 (USD Million)
Table 8 Market, By Technology, 20152022 (USD Million)
Table 9 Market for Surface Plasmon Resonance, By Region, 20152022 (USD Million)
Table 10 Market for Bio-Layer Interferometry, By Region, 20152022 (USD Million)
Table 11 Market for Isothermal Titration Calorimetry, By Region, 20152022 (USD Million)
Table 12 Market for Differential Scanning Calorimetry, By Region, 20152022 (USD Million)
Table 13 Market for Other Technologies, By Region, 20152022 (USD Million)
Table 14 Market, By Application, 20152022 (USD Million)
Table 15 Market for Binding Kinetics, By Region, 20152022 (USD Million)
Table 16 Market for Binding Thermodynamics, By Region, 20152022 (USD Million)
Table 17 Market for Endogenous Receptor Detection, By Region, 20152022 (USD Million)
Table 18 Label-Free Detection Market for Hit Confirmation, By Region, 20152022 (USD Million)
Table 19 Market for Lead Generation, By Region, 20152022 (USD Million)
Table 20 Market for Other Applications, By Region, 20152022 (USD Million)
Table 21 Market, By End User, 20152022 (USD Million)
Table 22 Market for Pharmaceutical & Biotechnology Companies, By Region, 20152022 (USD Million)
Table 23 Market for Academic & Research Institutes, By Region, 20152022 (USD Million)
Table 24 Market for Contract Research Organizations, By Region, 20152022 (USD Million)
Table 25 Market for Other End Users, By Region, 20152022 (USD Million)
Table 26 Market, By Region, 20152022 (USD Million)
Table 27 North America: Label-Free Detection Market, By Country, 20152022 (USD Million)
Table 28 North America: Market, By Product, 20152022 (USD Million)
Table 29 North America: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 30 North America: Market, By Technology, 20152022 (USD Million)
Table 31 North America: Market, By Application, 20152022 (USD Million)
Table 32 North America: Market, By End User, 20152022 (USD Million)
Table 33 US: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 34 US: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 35 US: Market, By Technology, 20152022 (USD Million)
Table 36 US: Market, By Application, 20152022 (USD Million)
Table 37 US: Market, By End User, 20152022 (USD Million)
Table 38 Canada: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 39 Canada: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 40 Canada: Market, By Technology, 20152022 (USD Million)
Table 41 Canada: Market, By Application, 20152022 (USD Million)
Table 42 Canada: Market, By End User, 20152022 (USD Million)
Table 43 Europe: Label-Free Detection Market, By Country/Region, 20152022 (USD Million)
Table 44 Europe: Market, By Product, 20152022 (USD Million)
Table 45 Europe: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 46 Europe: Market, By Technology, 20152022 (USD Million)
Table 47 Europe: Market, By Application, 20152022 (USD Million)
Table 48 Europe: , By End User, 20152022 (USD Million)
Table 49 Germany: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 50 Germany: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 51 Germany: Market, By Technology, 20152022 (USD Million)
Table 52 Germany: Market, By Application, 20152022 (USD Million)
Table 53 Germany: Market, By End User, 20152022 (USD Million)
Table 54 UK: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 55 UK: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 56 UK: Market, By Technology, 20152022 (USD Million)
Table 57 UK: Market, By Application, 20152022 (USD Million)
Table 58 UK: Market, By End User, 20152022 (USD Million)
Table 59 France: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 60 France: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 61 France: Market, By Technology, 20152022 (USD Million)
Table 62 France: Market, By Application, 20152022 (USD Million)
Table 63 France: Market, By End User, 20152022 (USD Million)
Table 64 Italy: Market, By Product, 20152022 (USD Million)
Table 65 Italy: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 66 Italy: Market, By Technology, 20152022 (USD Million)
Table 67 Italy: Market, By Application, 20152022 (USD Million)
Table 68 Italy: Market, By End User, 20152022 (USD Million)
Table 69 Spain: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 70 Spain: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 71 Spain: Market, By Technology, 20152022 (USD Million)
Table 72 Spain: Market, By Application, 20152022 (USD Million)
Table 73 Spain: Market, By End User, 20152022 (USD Million)
Table 74 RoE: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 75 RoE: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 76 RoE: Market, By Technology, 20152022 (USD Million)
Table 77 RoE: Market, By Application, 20152022 (USD Million)
Table 78 RoE: Market, By End User, 20152022 (USD Million)
Table 79 Asia Pacific: Label-Free Detection Market, By Country/Region, 20152022 (USD Million)
Table 80 Asia Pacific: Market, By Product, 20152022 (USD Million)
Table 81 Asia Pacific: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 82 Asia Pacific: Market, By Technology, 20152022 (USD Million)
Table 83 Asia Pacific: Market, By Application, 20152022 (USD Million)
Table 84 Asia Pacific: Market, By End User, 20152022 (USD Million)
Table 85 China: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 86 China: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 87 China: Market, By Technology, 20152022 (USD Million)
Table 88 China: Market, By Application, 20152022 (USD Million)
Table 89 China: Market, By End User, 20152022 (USD Million)
Table 90 Japan: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 91 Japan: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 92 Japan: Market, By Technology, 20152022 (USD Million)
Table 93 Japan: Market, By Application, 20152022 (USD Million)
Table 94 Japan: Market, By End User, 20152022 (USD Million)
Table 95 India: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 96 India: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 97 India: Market, By Technology, 20152022 (USD Million)
Table 98 India: Market, By Application, 20152022 (USD Million)
Table 99 India: Market, By End User, 20152022 (USD Million)
Table 100 RoAPAC: Label-Free Detection Market, By Product, 20152022 (USD Million)
Table 101 RoAPAC: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 102 RoAPAC: Market, By Technology, 20152022 (USD Million)
Table 103 RoAPAC: Market, By Application, 20152022 (USD Million)
Table 104 RoAPAC: Market, By End User, 20152022 (USD Million)
Table 105 RoW: Label-Free Detection Market, By Country/Region, 20152022 (USD Million)
Table 106 RoW: Market, By Product, 20152022 (USD Million)
Table 107 RoW: Label-Free Detection Consumables Market, By Type, 20152022 (USD Million)
Table 108 RoW: Market, By Technology, 20152022 (USD Million)
Table 109 RoW: Market, By Application, 20152022 (USD Million)
Table 110 RoW: Market, By End User, 20152022 (USD Million)
List of Figures (39 Figures)
Figure 1 Label-Free Detection Market Segmentation
Figure 2 Research Design
Figure 3 Bottom-Up Approach
Figure 4 Top-Down Approach
Figure 5 Data Triangulation Methodology
Figure 6 Market, By Product, 2017 vs 2022 (USD Million)
Figure 7 Market, By Consumables, 2017 vs 2022 (USD Million)
Figure 8 Market, By Application, 2017 vs 2022 (USD Million)
Figure 9 Market, Technology, 2017 vs 2022 (USD Million)
Figure 10 Market, End User, 2017 vs 2022 (USD Million)
Figure 11 Market, By Region, 2017 vs 2022 (USD Million)
Figure 12 Innovations in Label-Free Detection Technologies to Drive Market Growth
Figure 13 Surface Plasmon Resonance to Dominate the APAC Market in 2017
Figure 14 Instrument Segment to Register the Highest CAGR During the Forecast Period
Figure 15 APAC to Register the Highest CAGR Between 2017 & 2022
Figure 16 Global Market: Drivers, Restraints, Opportunities, and Challenges
Figure 17 The Instruments Segment is Expected to Dominate the Label-Free Detection Market During the Forecast Period
Figure 18 Surface Plasmon Resonance Technology Segment to Dominate the Market During the Forecast Period
Figure 19 Binding Kinetics Application Segment to Dominate the Label-Free Detection Market During the Forecast Period
Figure 20 Pharmaceutical & Biotechnology Companies to Dominate the Market in 2022
Figure 21 Asia Pacific to Register the Highest Growth Rate in the Label-Free Detection Market During the Forecast Period
Figure 22 North America: Market Snapshot
Figure 23 Instruments Segment to Dominate the US Market in 2017
Figure 24 Europe: Market Snapshot
Figure 25 Bio-Layer Interferometry Segment to Register the Highest CAGR in the German Market During the Forecast Period
Figure 26 Asia Pacific: Market Snapshot
Figure 27 RoW: Market Snapshot
Figure 28 Global Market: Market Share (2016)
Figure 29 General Electric: Company Snapshot (2016)
Figure 30 Danaher: Company Snapshot (2016)
Figure 31 Perkinelmer: Company Snapshot (2016)
Figure 32 Ametek: Company Snapshot (2016)
Figure 33 Roche: Company Snapshot (2016)
Figure 34 Spectris: Company Snapshot (2016)
Figure 35 Waters Corporation: Company Snapshot (2016)
Figure 36 Corning Incorporated: Company Snapshot (2016)
Figure 37 Horiba, Ltd.: Company Snapshot (2016)
Figure 38 Shimadzu Corporation: Company Snapshot (2016)
Figure 39 Hitachi High Tech: Company Snapshot (2015)
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Growth opportunities and latent adjacency in Label-Free Detection Market