Protein A Resin Market

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Protein A Resin Market by Product (Agarose-based, Glass/Silica-based), Type (Recombinant Protein A, Natural Protein A), Application (Antibody Purification, Immunoprecipitation), & End User - Global Forecast to 2025

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Report Code: AST 7818 Jan, 2021, by marketsandmarkets.com

[140 Pages Report] The protein A resin market is expected to reach USD 1.9 billion by 2025 from USD 1.1 billion in 2020, at a CAGR of 11.4% during the forecast period. The growth in this market is mainly driven by the growing demand for disposable pre-packed columns, increasing demand for therapeutic antibodies, and the increasing pharmaceutical R&D spending are expected to drive the growth of this market during the forecast period. However, the high cost of resins is expected to limit the growth of this market.

Protein A Resin Market

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COVID-19 Impact on the Protein A Resin Market

For the past 30 years, monoclonal antibodies have transformed the way we treat various diseases�they have proven to be more effective, better tolerated, and easier to deliver than other treatments. Researchers are optimistic that monoclonal antibodies could help prevent and treat early infections of COVID-19. Several monoclonal antibodies that are licensed or in development for other diseases are in clinical trials for COVID-19. One of these is adalimumab, used to treat arthritis and Crohn's disease; the University of Oxford recently launched a trial to look at its potential to treat people in care homes, funded by the COVID-19 Therapeutics Accelerator. Eli Lilly and Company (US), in collaboration with AbCellera (Canada), launched the first human study of a potential COVID-19 antibody treatment in June 2020. Other safety clinical trials have followed, including studies by AstraZeneca (UK), Celltrion (South Korea), and Regeneron (US). Since protein A resin is required for the purification of antibodies, the increase in mAb production due to the current pandemic is likely to spur the growth of the protein A resin market.

Protein A Resin Market Dynamics

Drivers: Increasing demand for therapeutic antibodies

Chromatography is an essential step in the purification of monoclonal antibodies (mAbs). Over the past decade, there has been a tremendous increase in the demand for monoclonal antibodies in oncology and several other therapeutic areas, including neurological, autoimmune, and inflammatory disorders. As a result, almost all major pharmaceutical companies are focusing on the R&D of therapeutic antibodies.

In the purification of monoclonal antibodies, anionic impurities, such as nucleic acids and endotoxins, are removed through chromatography. In drug discovery applications, this process consumes a large amount of resins, as the usage is not limited to purification but also includes the study of the ionic interaction of molecules. Impurities such as albumin and transferrin are removed by size-exclusion chromatography (SEC). High levels of purification can be achieved through the use of protein A affinity resins. This is because antibodies selectively bind protein A ligands with the resins. This is expected to drive the demand for protein A resins during the forecast period.

Restrains: High cost of resins

Protein A resins cost around 5-10 times more than other types of resins. Though there are no alternative techniques that can achieve purification levels as high as protein A resins, their high cost makes end users look for alternatives. Some of the techniques that provide acceptable levels of purification include both chromatography and non-chromatography methods. mAb crystallization and precipitation by polyethylene glycol (PEG) precipitation are being explored as alternatives for protein A chromatography.

The impact of this restraining factor is more evident in emerging markets such as APAC and Latin America. However, with the entry of new market players, the cost of protein A resins is expected to come down significantly. The increasing pressure on major market players is expected to result in price reduction, as small market entrants are offering resins at far lower prices, while simultaneously offering comparable product quality.

Opportunities: Increasing number of CMOs and CROs

An increasing number of CMOs and CROs are offering their services to pharmaceutical companies across the globe. This is expected to offer potential growth opportunities to protein A resin manufacturers during the forecast period.

Pharmaceutical companies are increasingly relying on contract manufacturers in various areas of research to fulfill a number of basic needs, such as specialized competencies and cost reduction. The pharmaceutical contract manufacturing industry has experienced robust growth in recent years, and this trend is expected to continue in the coming years. The increasing pressure from several governments to reduce healthcare costs and declining R&D productivity have compelled core pharmaceutical producers to rely on contract manufacturing. Moreover, the rising demand for generic drugs in China and India is a key driver for CMO sales.

The Agarose-based Protein A segment is expected to command the largest market share in 2020.

Based on product, the protein A resin market is segmented into agarose-based protein A, glass/silica-based protein A, and organic polymer-based protein A. In 2020, the agarose-based protein A segment is expected to is expected to command the largest share of the protein A resin market. The large share of this segment can be attributed to the agarose being the most widely used matrix resin for the attachment of ligands that bind proteins.

The antibody purification segment is expected to command the largest market share e in 2020.

Based on application, the protein A resin market is segmented into antibody purification and immunoprecipitation. In 2020, the antibody purification application segment is expected to command the largest share of the protein A resin market. The large share of this segment can primarily be attributed to the increasing demand for monoclonal antibodies for therapeutic as well as research purposes, which has driven the demand for protein A resins used in the downstream processing of these antibodies.

The pharmaceutical and biopharmaceutical companies segment to hold the largest market share in 2020.

Based on end user, the protein A resin market is segmented into pharmaceutical & biopharmaceutical companies, academic research institutes, and other end users. In 2020, the pharmaceutical and biopharmaceutical companies segment is expected to command the largest share of the protein A resin market. The increasing R&D expenditure of pharmaceutical and biopharmaceutical companies is the major factor driving the growth of this end-user segment.

North America is expected to dominate the protein A resin market during the forecast period

Geographically, North America is expected to dominate the global the protein A resin market in 2019, while the Asia Pacific region is expected to register the highest CAGR during the forecast period. The high growth in this region can be attributed to the increased R&D activities, as APAC has emerged as a key pharmaceutical and biopharmaceutical research hub. Considering this, a number of key pharmaceutical and biopharmaceutical companies have set up their research centers in the region. Also, local major players such as Ranbaxy, Dr. Reddy�s, Cipla, Lupin, and Cadila are actively involved in research on biosimilars and generic drugs.

Protein A Resin Market by Region

Key Market Players

GE Healthcare (US), Repligen Corporation (US), Merck Millipore (Germany), are some of the leading players of the protein A resin market.

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Scope of the Report

Report Metric	Details
Market size available for years	2018�2025
Base year considered	2019
Forecast period	2020�2025
Forecast unit	Value (USD Billion)
Segments covered	Product, Type, Application, End User, and Region
Geographies covered	North America (US & Canada), Europe (Germany, UK, France, Italy, Spain, RoE), Asia Pacific (China, Japan, India, RoAPAC), and RoW
Companies covered	Major 20 players included, including GE Healthcare (US), Merck Millipore (Germany), Repligen Corporation (US), Thermo Fisher Scientific (US), Tosoh Bioscience (Japan), Purolite Corporation (US), Novasep Holding SAS (France), Agilent Technologies (US), GenScript Biotech Corporation (China), PerkinElmer (US), Bio-Rad Laboratories (US), Orochem (US), Kaneka Corporation (Japan), Abcam (UK), Agarose Bead Technologies (US), Avantor (US), JSR Life Sciences (US), Bio-Works Technologies (Sweden), Amikozen Co. Ltd. (US), and Takara Bio Inc. (Japan).

This research report categorizes the protein A resin market based on product, type, application, end user, and region.

By Product

Agarose-based Protein A
Glass/Silica-based Protein A
Organic Polymer-based Protein A

By Type

Recombinant Protein A
Natural Protein A

By Application

Antibody Purification
Immunoprecipitation

By End-User

Pharmaceutical & Biopharmaceutical Companies
Academic Research Institutes
Other End Users

By Region

North America
- US
- Canada
Europe
- Germany
- UK
- France
- Italy
- Spain
- RoE
Asia Pacific
- China
- Japan
- India
- RoAPAC
RoW

Recent Developments

In 2018, Merck Millipore (Germany) opened a new manufacturing and distribution center in India for its Life Science business.
In 2017, Repligen Corporation (US) merged with Spectrum Inc. (US), a leader in membrane separation technologies for the pharmaceutical, bioprocess, diagnostic, and research industries. This merger was aimed at accelerating the growth of its filtration business and enhancing its position as a leading developer of single-use and continuous manufacturing technologies for bioprocessing.
In 2017, Purolite Life Sciences collaborated with ChromaTan Corporation (US), which provides chromatography solutions. The development increased the production of protein A resins by up to 15 times.

Frequently Asked Questions (FAQ):

What is the market size of the protein A resin Market?

The global protein A resin market is expected to reach USD 1.9 billion by 2025 from USD 1.1 billion in 2020, at a CAGR of 11.4% during the forecast period.

What are some of the major drivers for this market?

The key factors propelling the growth of this market are growing demand for disposable pre-packed columns, increasing demand for therapeutic antibodies, and the increasing pharmaceutical R&D spending

Who are the major players in the protein A resin market?

GE Healthcare (US), Merck Millipore (Germany), Repligen Corporation (US), Thermo Fisher Scientific (US), Tosoh Bioscience (Japan), Purolite Corporation (US), and Novasep Holding SAS (France), are considered to be the leading players in the protein A resin market.

What is the impact of COVID-19 on the protein A resin market?

The pandemic has led to increased activities in the research and development of pharmaceuticals. It has pressurized all the major pharmaceutical and biopharmaveutical vompanies to develop a vaccine that provides immunity against COVID-19. Owing to this increased pressure companies are investing heavily in research and development activities. This has led to an increased production of already approved monoclonal antibodies and aggressive clinical trials to develop new mAbs. Since protein A resin is required in the downstream process of antibodies, an increased production of the later has leed to an increase in the use of protein A resin for purofication purposes. Thus, COVID-19 is expected to positively impact the protein A resin market.

Which region has the highest growth potential in the protein A resin market?

The market in the APAC is expected to grow at the highest CAGR over the next five years. Increasing demand from key markets such as Japan and China and the rising research and development initiatives in the region to drive market growth in APAC. .

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TABLE OF CONTENTS

1 INTRODUCTION (Page No. - 20)
    1.1 OBJECTIVES OF THE STUDY
    1.2 MARKET DEFINITION
    1.3 INCLUSIONS AND EXCLUSIONS
           1.3.1 MARKETS COVERED
           FIGURE 1 PROTEIN A RESIN MARKET SEGMENTATION
           1.3.2 YEARS CONSIDERED FOR THE REPORT
    1.4 CURRENCY
    1.5 LIMITATIONS
    1.6 STAKEHOLDERS

2 RESEARCH METHODOLOGY (Page No. - 23)
    2.1 RESEARCH DATA
    2.2 RESEARCH METHODOLOGY STEPS
           FIGURE 2 RESEARCH METHODOLOGY: PROTEIN A RESIN MARKET
           FIGURE 3 RESEARCH DESIGN
           2.2.1 SECONDARY DATA
                    2.2.1.1 Key data from secondary sources
           2.2.2 PRIMARY DATA
           FIGURE 4 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION
           FIGURE 5 PRIMARY SOURCES
                    2.2.2.1 Key data from primary sources
    2.3 MARKET SIZE ESTIMATION METHODOLOGY
           FIGURE 6 RESEARCH METHODOLOGY: HYPOTHESIS BUILDING
           FIGURE 7 MARKET SIZE ESTIMATION: REVENUE SHARE ANALYSIS
    2.4 MARKET DATA ESTIMATION AND TRIANGULATION
           FIGURE 8 DATA TRIANGULATION METHODOLOGY
    2.5 ASSUMPTIONS FOR THE STUDY
    2.6 COVID-19-SPECIFIC ASSUMPTIONS

3 EXECUTIVE SUMMARY (Page No. - 32)
           FIGURE 9 PROTEIN A RESIN MARKET, BY PRODUCT, 2020 VS. 2025 (USD MILLION)
           FIGURE 10 PROTEIN A RESIN MARKET, BY TYPE, 2020 VS. 2025 (USD MILLION)
           FIGURE 11 PROTEIN A RESIN MARKET, BY APPLICATION, 2020 VS. 2025 (USD MILLION)
           FIGURE 12 PROTEIN A RESIN MARKET, BY END USER, 2020 VS. 2025 (USD MILLION)
           FIGURE 13 GEOGRAPHICAL SNAPSHOT OF THE PROTEIN A RESIN MARKET

4 PREMIUM INSIGHTS (Page No. - 36)
    4.1 GLOBAL PROTEIN A RESIN MARKET OVERVIEW
           FIGURE 14 ADVANTAGES OF PROTEIN A RESINS HAVE DRIVEN THEIR ADOPTION
    4.2 NORTH AMERICA: PROTEIN A RESIN MARKET, 2019
           FIGURE 15 US ACCOUNTED FOR THE LARGEST SHARE OF THE NORTH AMERICAN MARKET IN 2019
    4.3 PROTEIN A RESIN MARKET, BY PRODUCT & SERVICE
           FIGURE 16 AGAROSE-BASED PROTEIN A SEGMENT TO ACCOUNT FOR THE LARGEST MARKET SHARE IN 2020
    4.4 PROTEIN A RESIN MARKET: GEOGRAPHIC GROWTH OPPORTUNITIES
           FIGURE 17 ASIA PACIFIC MARKET TO WITNESS THE HIGHEST GROWTH DURING THE FORECAST PERIOD

5 MARKET OVERVIEW (Page No. - 39)
    5.1 INTRODUCTION
    5.2 MARKET DYNAMICS
           FIGURE 18 PROTEIN A RESIN MARKET: DRIVERS, RESTRAINTS, AND OPPORTUNITIES
           5.2.1 DRIVERS
                    5.2.1.1 Growing demand for disposable pre-packed columns
           TABLE 1 ADVANTAGES OF PRE-PACKED COLUMNS
                    5.2.1.2 Increasing demand for therapeutic antibodies
                    5.2.1.3 Increasing pharmaceutical R&D spending
           5.2.2 RESTRAINTS
                    5.2.2.1 High cost of resins
                    5.2.2.2 Dearth of skilled professionals
           5.2.3 OPPORTUNITIES
                    5.2.3.1 Increasing number of CMOs and CROs
           FIGURE 19 PHARMACEUTICAL CONTRACT MANUFACTURING MARKET GROWTH, 2019�2024
                    5.2.3.2 Increasing demand for biosimilars
           FIGURE 20 GROWTH OF THE BIOSIMILARS MARKET, 2018�2023
           TABLE 2 LIST OF KEY BIOLOGICS UNDER THE THREAT OF PATENT EXPIRY
    5.3 PRICING ANALYSIS: PROTEIN A RESIN MARKET
    5.4 PORTER�S FIVE FORCES ANALYSIS
           FIGURE 21 PORTER�S FIVE FORCES ANALYSIS
           5.4.1 THREAT OF SUBSTITUTES
           5.4.2 BARGAINING POWER OF SUPPLIERS
           5.4.3 BARGAINING POWER OF BUYERS
           5.4.4 THREAT OF NEW ENTRANTS
           5.4.5 INTENSITY OF COMPETITIVE RIVALRY
    5.5 IMPACT OF COVID-19 ON THE PROTEIN A RESIN MARKET
    5.6 VALUE CHAIN ANALYSIS
           FIGURE 22 MAJOR VALUE IS ADDED DURING THE MANUFACTURING AND ASSEMBLY PHASE
           5.6.1 RESEARCH & DEVELOPMENT
           5.6.2 MANUFACTURING & ASSEMBLY
           5.6.3 DISTRIBUTION, MARKETING & SALES, AND POST-SALES SERVICES
    5.7 SUPPLY CHAIN ANALYSIS
           5.7.1 PROMINENT COMPANIES
           5.7.2 SMALL AND MEDIUM-SIZED ENTERPRISES
           5.7.3 END USERS
           FIGURE 23 DISTRIBUTION�A STRATEGY PREFERRED BY PROMINENT COMPANIES
           FIGURE 24 ECOSYSTEM ANALYSIS OF THE PROTEIN A RESIN MARKET

6 PROTEIN A RESIN MARKET, BY PRODUCT (Page No. - 52)
    6.1 INTRODUCTION
           TABLE 3 PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
    6.2 AGAROSE-BASED PROTEIN A
           6.2.1 BENEFITS OFFERED BY AGAROSE MAKES IT THE PREFERRED CHOICE FOR PROTEIN PURIFICATION
           TABLE 4 AGAROSE-BASED PROTEIN A MARKET, BY REGION, 2018�2025 (USD MILLION)
           TABLE 5 NORTH AMERICA: AGAROSE-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 6 EUROPE: AGAROSE-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 7 APAC: AGAROSE-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
    6.3 GLASS/SILICA-BASED PROTEIN A
           6.3.1 LOW PH TOLERANCE OF SILICA-BASED RESINS TO LIMIT THEIR MARKET GROWTH
           TABLE 8 GLASS/SILICA-BASED PROTEIN A MARKET, BY REGION, 2018�2025 (USD MILLION)
           TABLE 9 NORTH AMERICA: GLASS/SILICA-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 10 EUROPE: GLASS/SILICA-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 11 APAC: GLASS/SILICA-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
    6.4 ORGANIC POLYMER-BASED PROTEIN A
           6.4.1 INCREASING POPULARITY OF ORGANIC POLYMERS TO DRIVE MARKET GROWTH
           TABLE 12 ORGANIC POLYMER-BASED PROTEIN A MARKET, BY REGION, 2018�2025 (USD MILLION)
           TABLE 13 NORTH AMERICA: ORGANIC POLYMER-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 14 EUROPE: ORGANIC POLYMER-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 15 APAC: ORGANIC POLYMER-BASED PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)

7 PROTEIN A RESIN MARKET, BY TYPE (Page No. - 59)
    7.1 INTRODUCTION
           TABLE 16 PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
    7.2 RECOMBINANT PROTEIN A
           7.2.1 COST-EFFICIENCY OF RECOMBINANT PROTEINS TO DRIVE MARKET GROWTH
           TABLE 17 RECOMBINANT PROTEIN A MARKET, BY REGION, 2018�2025 (USD MILLION)
           TABLE 18 NORTH AMERICA: RECOMBINANT PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 19 EUROPE: RECOMBINANT PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 20 APAC: RECOMBINANT PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
    7.3 NATURAL PROTEIN A
           7.3.1 ADVANTAGES OF RECOMBINANT PROTEIN A HAVE RESTRICTED THE MARKET POTENTIAL OF NATURAL PROTEIN A
           TABLE 21 NATURAL PROTEIN A MARKET, BY REGION, 2018�2025 (USD MILLION)
           TABLE 22 NORTH AMERICA: NATURAL PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 23 EUROPE: NATURAL PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 24 APAC: NATURAL PROTEIN A MARKET, BY COUNTRY, 2018�2025 (USD MILLION)

8 PROTEIN A RESIN MARKET, BY APPLICATION (Page No. - 64)
    8.1 INTRODUCTION
           TABLE 25 PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
    8.2 ANTIBODY PURIFICATION
           8.2.1 ANTIBODY PURIFICATION SEGMENT TO DOMINATE THE MARKET DURING THE FORECAST PERIOD
           TABLE 26 PROTEIN A RESIN MARKET FOR ANTIBODY PURIFICATION, BY REGION, 2018�2025 (USD MILLION)
    8.3 IMMUNOPRECIPITATION
           8.3.1 IMMUNOPRECIPITATION SEGMENT TO GROW AT A LOWER CAGR DURING THE FORECAST PERIOD
           TABLE 27 PROTEIN A RESIN MARKET FOR IMMUNOPRECIPITATION, BY REGION, 2018�2025 (USD MILLION)

9 PROTEIN A RESIN MARKET, BY END USER (Page No. - 67)
    9.1 INTRODUCTION
           TABLE 28 PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
    9.2 PHARMACEUTICAL & BIOPHARMACEUTICAL COMPANIES
           9.2.1 PROTEIN A RESIN IS EXTENSIVELY USED TO PRODUCE BIOLOGICAL DRUGS
           FIGURE 25 SPENDING ON BIOPHARMACEUTICAL RESEARCH, 2005�2020 (USD BILLION)
           TABLE 29 PROTEIN A RESIN MARKET FOR PHARMACEUTICAL & BIOPHARMACEUTICAL COMPANIES, BY REGION, 2018�2025 (USD MILLION)
    9.3 ACADEMIC RESEARCH INSTITUTES
           9.3.1 BOOMING R&D IN DRUG DISCOVERY LIKELY TO INCREASE THE USE OF PROTEIN A RESINS
           TABLE 30 PROTEIN A RESIN MARKET FOR ACADEMIC RESEARCH INSTITUTES, BY REGION, 2018�2025 (USD MILLION)
    9.4 OTHER END USERS
           TABLE 31 PROTEIN A RESIN MARKET FOR OTHER END USERS, BY REGION, 2018�2025 (USD MILLION)

10 PROTEIN A RESIN MARKET, BY REGION (Page No. - 71)
     10.1 INTRODUCTION
           TABLE 32 PROTEIN A RESIN MARKET, BY REGION, 2018�2025 (USD MILLION)
     10.2 NORTH AMERICA
           FIGURE 26 NORTH AMERICA: PROTEIN A RESIN MARKET SNAPSHOT
           TABLE 33 NORTH AMERICA: PROTEIN A RESIN MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 34 NORTH AMERICA: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 35 NORTH AMERICA: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 36 NORTH AMERICA: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 37 NORTH AMERICA: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.2.1 US
                        10.2.1.1 Booming R&D investment in the pharmaceutical industry to propel market growth
           TABLE 38 US: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 39 US: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 40 US: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 41 US: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.2.2 CANADA
                        10.2.2.1 Government initiatives focused on boosting the pharmaceutical industry to drive market growth
           TABLE 42 CANADA: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 43 CANADA: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 44 CANADA: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 45 CANADA: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
     10.3 EUROPE
           FIGURE 27 EUROPE: PROTEIN A RESIN MARKET SNAPSHOT
           TABLE 46 EUROPE: PROTEIN A RESIN MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 47 EUROPE: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 48 EUROPE: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 49 EUROPE: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 50 EUROPE: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.3.1 GERMANY
                        10.3.1.1 Flourishing biotechnology industry in the country to drive market growth
           TABLE 51 GERMANY: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 52 GERMANY: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 53 GERMANY: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 54 GERMANY: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.3.2 UK
                        10.3.2.1 Favorable R&D scenario in the country to support market growth
           TABLE 55 UK: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 56 UK: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 57 UK: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 58 UK: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.3.3 FRANCE
                        10.3.3.1 Favorable healthcare scenario to boost market growth in France
           TABLE 59 FRANCE: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 60 FRANCE: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 61 FRANCE: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 62 FRANCE: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.3.4 ITALY
                        10.3.4.1 Well-established pharmaceutical industry in the country to spur the demand for protein A resins
           TABLE 63 ITALY: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 64 ITALY: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 65 ITALY: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 66 ITALY: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.3.5 SPAIN
                        10.3.5.1 Presence of a large number of biotech R&D service providers to support market growth
           TABLE 67 SPAIN: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 68 SPAIN: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 69 SPAIN: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 70 SPAIN: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.3.6 REST OF EUROPE
           TABLE 71 ROE: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 72 ROE: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 73 ROE: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 74 ROE: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
     10.4 ASIA PACIFIC
           FIGURE 28 APAC: PROTEIN A RESIN MARKET SNAPSHOT
           TABLE 75 ASIA PACIFIC: PROTEIN A RESIN MARKET, BY COUNTRY, 2018�2025 (USD MILLION)
           TABLE 76 ASIA PACIFIC: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 77 ASIA PACIFIC: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 78 ASIA PACIFIC: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 79 ASIA PACIFIC: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.4.1 JAPAN
                        10.4.1.1 Increasing demand for generic drugs and monoclonal antibody biosimilars is driving resin consumption in the country
           TABLE 80 JAPAN: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 81 JAPAN: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 82 JAPAN: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 83 JAPAN: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.4.2 CHINA
                        10.4.2.1 Increased pharmaceutical R&D spending to drive market growth
           TABLE 84 CHINA: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 85 CHINA: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 86 CHINA: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 87 CHINA: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.4.3 INDIA
                        10.4.3.1 Growth of the pharma and biotech industries is leading to high demand for protein A resins in India
           TABLE 88 INDIA: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 89 INDIA: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 90 INDIA: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 91 INDIA: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
             10.4.4 REST OF ASIA PACIFIC
           TABLE 92 ROAPAC: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 93 ROAPAC: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 94 ROAPAC: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 95 ROAPAC: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)
     10.5 REST OF THE WORLD
           FIGURE 29 ROW: PROTEIN A RESIN MARKET SNAPSHOT
           TABLE 96 ROW: PROTEIN A RESIN MARKET, BY PRODUCT, 2018�2025 (USD MILLION)
           TABLE 97 ROW: PROTEIN A RESIN MARKET, BY TYPE, 2018�2025 (USD MILLION)
           TABLE 98 ROW: PROTEIN A RESIN MARKET, BY APPLICATION, 2018�2025 (USD MILLION)
           TABLE 99 ROW: PROTEIN A RESIN MARKET, BY END USER, 2018�2025 (USD MILLION)

11 COMPETITIVE LANDSCAPE (Page No. - 100)
     11.1 OVERVIEW
           FIGURE 30 KEY DEVELOPMENTS IN THE PROTEIN A RESIN MARKET, 2017�2019
     11.2 MARKET SHARE ANALYSIS
           FIGURE 31 PROTEIN A RESIN MARKET SHARE ANALYSIS (2019)
     11.3 COMPETITIVE LEADERSHIP MAPPING
             11.3.1 VISIONARY LEADERS
             11.3.2 INNOVATORS
             11.3.3 DYNAMIC DIFFERENTIATORS
             11.3.4 EMERGING COMPANIES
           FIGURE 32 PROTEIN A RESIN MARKET: COMPETITIVE LEADERSHIP MAPPING (2019)
     11.4 COMPETITIVE SCENARIO
             11.4.1 PRODUCT LAUNCHES
           TABLE 100 PRODUCT LAUNCHES (2017�2020)
             11.4.2 FUNDING
           TABLE 101 FUNDING (2017�2020)
             11.4.3 ACQUISITIONS
           TABLE 102 ACQUISITIONS (2017�2020)
             11.4.4 PARTNERSHIPS
           TABLE 103 PARTNERSHIPS (2017�2020)

12 COMPANY PROFILES (Page No. - 106)
(Business overview, Products offered, Recent developments, MNM view)*
     12.1 GE HEALTHCARE
           FIGURE 33 GE HEALTHCARE: COMPANY SNAPSHOT
     12.2 MERCK MILLIPORE
           FIGURE 34 MERCK MILLIPORE: COMPANY SNAPSHOT
     12.3 REPLIGEN CORPORATION
           FIGURE 35 REPLIGEN CORPORATION: COMPANY SNAPSHOT (2019)
     12.4 THERMO FISHER SCIENTIFIC, INC.
           FIGURE 36 THERMO FISHER SCIENTIFIC, INC.: COMPANY SNAPSHOT
     12.5 TOSOH BIOSCIENCE
           FIGURE 37 TOSOH CORPORATION: COMPANY SNAPSHOT
     12.6 PUROLITE CORPORATION
     12.7 NOVASEP HOLDING SAS
     12.8 AGILENT TECHNOLOGIES, INC.
           FIGURE 38 AGILENT TECHNOLOGIES, INC.: COMPANY SNAPSHOT
     12.9 GENSCRIPT BIOTECH CORPORATION
           FIGURE 39 GENSCRIPT BIOTECH CORPORATION: COMPANY SNAPSHOT (2018)
     12.10 PERKINELMER, INC.
           FIGURE 40 PERKINELMER, INC.: COMPANY SNAPSHOT
     12.11 BIO-RAD LABORATORIES, INC.
           FIGURE 41 BIO-RAD LABORATORIES, INC.: COMPANY SNAPSHOT
     12.12 OROCHEM
     12.13 ANEKA CORPORATION
           FIGURE 42 KANEKA CORPORATION: COMPANY SNAPSHOT
     12.14 ABCAM PLC.
     12.15 AGAROSE BEAD TECHNOLOGIES
     12.16 AVANTOR, INC.
     12.17 JSR LIFE SCIENCES
     12.18 BIO-WORKS TECHNOLOGIES
     12.19 TAKARA BIO
     12.20 GENERON
*Business overview, Products offered, Recent developments, MNM view might not be captured in case of unlisted companies.

13 APPENDIX (Page No. - 134)
     13.1 DISCUSSION GUIDE
     13.2 KNOWLEDGE STORE: MARKETSANDMARKETS� SUBSCRIPTION PORTAL
     13.3 AVAILABLE CUSTOMIZATIONS
     13.4 RELATED REPORTS
     13.5 AUTHOR DETAILS

The study involved four major activities in estimating the current size for the protein A resin market. Exhaustive secondary research was done to collect information on the market and its different subsegments. The next step was to validate these findings, assumptions, and sizing with industry experts across the value chain through primary research. Both top-down and bottom-up approaches were employed to estimate the complete market size. After that, market breakdown and data triangulation were used to estimate the market size of segments and subsegments.

Secondary Research

In the secondary research process, various secondary sources such as D&B Hoovers, Bloomberg Business, and Factiva have been referred to, to identify and collect information for the protein A resin market study. These secondary sources included annual reports, press releases & investor presentations of companies, white papers, certified publications, articles by recognized authors, gold standard & silver standard websites, regulatory bodies, and databases.

Primary Research

The protein A resin market comprises several stakeholders such as chromatography resins manufacturers, pre-packed column manufacturers, government and research organizations, chromatography resins distributors and suppliers, investment banks and private equity firms, and end users such as pharmaceutical and biotechnology companies, universities, and independent research organizations. Various primary sources from both the supply and demand sides of the market were interviewed to obtain qualitative and quantitative information. Mentioned below is the breakdown of primary respondents:
Breakdown of Primary Interviews

Protein A Resin Market Size, and Share

To know about the assumptions considered for the study, download the pdf brochure

Market Size Estimation

Both top-down and bottom-up approaches were used to estimate and validate the total size of the protein A resin market. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:

The key players in the industry and markets have been identified through extensive secondary research
The industry�s supply chain and market size, in terms of value, have been determined through primary and secondary research processes
All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources

Data Triangulation

After arriving at the overall protein A resin market size-using the market size estimation processes as explained above-the market was split into several segments and subsegments. To complete the overall market engineering process and to arrive at the exact statistics of each market segment and subsegment, the data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides in protein A resin industry

Report Objectives

To define, describe, and forecast the global protein A resin market based on product, type, application, end user, and region
To provide detailed information regarding the major factors influencing the growth of the market (such as drivers, restraints, opportunities, and challenges)
To strategically analyze micromarkets1 with respect to individual growth trends, prospects, and contributions to the overall market
To analyze the opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
To forecast the size of the market segments with respect to four main regions�North America, Europe, the Asia Pacific, and the Rest of the World (RoW)2
To profile the key players and comprehensively analyze their market shares and core competencies3
To track and analyze competitive developments such as acquisitions, product launches, expansions, agreements & collaborations, and approvals in the global protein A resin market

Available Customizations

With the given market data, MarketsandMarkets offers customizations as per the company�s specific needs. The following customization options are available for the protein A resin market report: