The report "Mice Model Market by Model Type (Inbred, Outbred, Hybrid), Service (Breeding, Rederivation), Application (Personalized Medicine), Technology (Microinjection, CRISPR/Cas9), Therapeutic Area (Oncology, Neurology), End User (CROs) - Global Forecast to 2030", is projected to reach USD 2.74 billion by 2030 from USD 1.70 billion in 2025, at a CAGR of 10.0% during the forecast period.
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The mice model market is experiencing strong growth due to several contributing factors. These include the expanding use of mice in preclinical research because of their genetic and physiological similarities to humans, the rising implementation of mouse clinical trials (MCTs), and growing interest in personalized medicine, especially in oncology. Additionally, innovations in genetic engineering, such as CRISPR and increasing demand for disease-specific models, are expected to accelerate market growth during the forecast period.
By model type, the inbred mice segment accounted for the largest share of the market in 2024.
The market is categorized by model type into inbred mice, genetically engineered mice, hybrid/congenic mice, and outbred mice. In 2024, the inbred mice segment accounted for the largest share of the market. Inbred mice are developed through at least 20 generations of sibling or parent–offspring matings, producing genetically identical strains known as isogenic mice. Their uniform genetic background supports reproducible results across studies and laboratories. These models are used in research areas including pharmacology, carcinogenesis, monoclonal antibody production, tissue grafts, and cardiovascular studies. In behavioral research, inbred mice help isolate genetic influences on traits like memory, anxiety, and social interaction. In oncology, they support investigations into tumor development and therapy response. Their genetic consistency makes them suitable for validating new therapeutic agents, diagnostics, and vaccines.
In 2024, the CRISPR/Cas9 segment accounted for the largest share of the mice model market.
The mice model market is segmented by technology into CRISPR/Cas9, microinjection, embryonic stem cell injection, nuclear transfer, and other technologies. In 2024, the CRISPR/Cas9 segment accounted for the largest share of the market. This domination of the CRISPR/Cas9 segment can be attributed to its efficient and precise genome editing application. CRISPR/Cas9 systems use short guide RNAs and the Cas9 endonuclease to induce targeted DNA cleavage, enabling gene knockouts, base editing, and transgenesis. This method allows direct gene editing at the single-cell embryo stage, bypassing traditional breeding cycles and reducing timelines for generating modified strains. CRISPR also supports multiplexed editing, allowing simultaneous modification of multiple genes, which streamlines high-throughput in vivo genetic screening. For instance, a study published in Nature in October 2024 demonstrated both in vitro and in vivo CRISPR-Cas9 screening in aged Cas9-expressing mice, identifying over 300 gene knockouts and validating 24 targets for enhanced neurogenesis. Integrating CRISPR systems in transgenic model development and functional genomics has driven adoption among research institutions and pharmaceutical developers, establishing the technology’s leading market position.
By region, North America accounted for the largest market share in 2024.
In 2024, North America accounted for the largest market share of the mice model market, driven by established infrastructure for biomedical research, consistent regulatory oversight, and significant market participants. The US is the primary revenue contributor due to the concentration of contract research organizations, academic research centers, and biotechnology firms. Companies such as Charles River Laboratories (US), The Jackson Laboratory (US), and Inotiv (US) operate large-scale breeding and research facilities across the region, offering comprehensive services that include genetically engineered model development and preclinical testing.
Some of the leading players in the market include Charles River Laboratories (US), Inotiv (US), THE JACKSON LABORATORY (US), JSR Corporation (Japan), Biocytogen (China), Trans Genic Inc. (Japan) Harbour BioMed (China), genOway (France), GemPharmatech (China), Cyagen (US), Ozgene Pty Ltd (Australia), Taconic Biosciences, Inc. (US), TransCure bioServices (France), Vivo Bio Tech Ltd (India), ingenious targeting laboratory (US), Janvier Labs (France), Champions Oncology, Inc (US), and Vitalstar Biotechnology Co., Ltd. (China), among others.
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