The report "Tangential Flow Filtration Market by Product (Single Use Systems, Cassettes, Capsules), Material (PES, PVDF), Technique (Ultrafiltration), Application (Protein, Vaccine, API, Cell Separation), Scale of Operation (R&D), End User - Global Forecast to 2030", is projected to reach USD 3.20 billion by 2030 from an estimated USD 1.86 billion in 2025, at a CAGR of 11.4% during the forecast period.
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Some factors contributing to the growth of the global tangential flow filtration market include advantages of TFF over standard flow filtration, the integration of single-use technologies, rising adherence to GMP guidelines, increasing investments from pharmaceutical companies, and the overall expansion of the biopharmaceutical industry. However, the high capital investments required to set up new production facilities are expected to hinder market growth.
By product, the membrane filter devices segment accounted for the largest share of the tangential flow filtration market in 2024.
By product, the tangential flow filtration market is segmented into membrane filter devices, systems, and other TFF products. Systems are further segmented into single-use systems and reusable systems. The membrane filter devices segment is further categorized into cassettes and cartridges & capsules. The membrane filter devices segment dominated the market in 2024. The largest share of the segment is attributed to continuous innovation in membrane materials and configurations, enabling improved throughput, selectivity, and fouling resistance. This segment also benefits from broad compatibility with automated and single-use systems, making integration into evolving bioprocessing platforms easier.
By end user, the pharmaceutical & biotechnology companies segment is estimated to register the highest growth during the forecast period.
Based on end user, the tangential flow filtration market is segmented into pharmaceutical & biotechnology companies, CMOs & CROs, and academic & research institutes. The pharmaceutical & biotechnology companies’ segment is estimated to register the highest growth rate during the forecast period, driven by the rising demand for biologics, biosimilars, and advanced therapies such as mRNA vaccines and gene therapies. These companies invest heavily in capacity expansion, process intensification, and modular manufacturing, where TFF plays a vital role in downstream purification and formulation.
The Asia Pacific region is expected to register the highest CAGR during the forecast period.
Based on the region, the tangential flow filtration market is segmented into six regions: North America, Europe, the Asia Pacific, Latin America, the Middle East, and Africa. The Asia Pacific region is expected to register the highest growth rate during the forecast period, owing to the rapid expansion of biopharmaceutical manufacturing capabilities, particularly in countries like China, India, and South Korea. The increasing government support, rising biologics & biosimilars production, and increasing investments by global & regional pharmaceutical companies are accelerating the adoption of advanced filtration technologies, including TFF.
The key players in the tangential flow filtration market include Danaher Corporation (US), Merck KGaA (Germany), Sartorius AG (Germany), Repligen Corporation (US), Parker Hannifin Corporation (US), ANDRITZ (Austria), Alfa Laval Corporate AB (Sweden), Solaris Biotechnology Srl (Italy), Kovalus Separation Solutions (US), Synder Filtration, Inc. (US), Antylia Scientific (US), FORMULATRIX (US), ABEC, Inc. (US), VERDOT (France), Meissner Filtration Products, Inc. (US), and Sterlitech Corporation US), APPLEXION (France), among others.
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