The global protein purification and isolation market is poised to grow at a CAGR of 6% to 7% during the forecast period (2015 to 2020). Factors such as increased research in the pharmaceutical and biotechnological arenas, growing need to identify new ligands and rapid purification kits to rapidly screen, prepare, purify, and concentrate protein samples will fuel the market growth. Increased funding from both public and private research bodies for research and development, technological advancements, and growing research in the field of structure-based drug design are factors that are driving the growth of this market. The protein purification and isolation market is growing at a significant rate due to increase in the R&D for proteomics and technological advancements in this field. Various application areas for protein purification and isolation are protein-protein interaction studies, target identification, drug screening, protein therapeutics, biomarker discovery, disease monitoring, and diagnostic tests. A growing demand for protein purification in these application areas, specifically for protein-protein interaction studies, target identification, drug screening, and biomarker discovery studies is expected to fuel the growth in the protein purification and isolation technologies market in the coming years.
On the basis of products, the protein purification and isolation technologies market is broadly segmented into instruments and consumables. In 2014, the consumables segment accounted for a major share of the protein purification and isolation market. A growing demand for protein purification reagents, in line with an increasing number of protein-based research studies and diagnostic tests is expected to contribute to the growth of the consumables market during the forecast period.
Affinity tags are widely used for protein purification processes and remain a significant driver of the chromatography-based protein purification market due to its ability to achieve high-purity proteins in a single step. The most commonly used affinity tags are polyhistidine (His-tag), glutathione S-transferase (GST-tag), and streptavidin (strep-tag). On the other hand, ion exchange and hydrophobic charge interaction chromatography (HCIC) are expected to maintain a high customer base, particularly for preparative or large-scale applications, as users often employ multiple technologies in the protein purification process for their purification needs.
In the application segment, protein-protein interaction studies accounted for the largest share of the total market in 2014. Some of the major factors that are driving the global protein purification and isolation market are increasing adoption of automated protein purification instruments, increasing adoption of single use technology, and increase in R&D involving protein purification techniques. In addition, growing awareness and innovation of new protein purification techniques are driving the global protein purification and isolation market. However, high cost of the instruments, soaring research and development cost, difficulty in developing one-size-fits-all purification kits, and dearth of skilled professionals are restraining the growth of the global protein purification and isolation market.
Geographically, in 2014, the global protein purification and isolation market was dominated by North America, followed by Europe. The high share of North America can be attributed to the increased R&D investment and broad technical applications of protein purification and isolation in the region. Asia is expected to experience the highest growth rate in the next few years for the global protein purification and isolation market. China and India are expected to be the fastest-growing protein purification and isolation markets in the Asian region owing to the increased R&D investments and rising government funding.
Protein Purification & Isolation Market by Technology (Precipitation, Dialysis, Electrophoresis, Western Blotting, Ion Exchange & Affinity Chromatography) by Product (Instruments, Kits, Reagents, Resins) by Application & End User - Global Forecast to 2020
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