Patient Derived Xenografts/PDX Models Market worth $0.66 billion in 2030
The report "Patient Derived Xenografts/PDX Models Market by Type (Mouse, Rat), Service (Model Creation, Characterization), Implantation Method (Subcutaneous), Tumor Type (Respiratory, GI, Gynecological), Application (Preclinical, Biomarker) - Global Forecast to 2030", is expected to reach USD 0.66 billion in 2030 from USD 0.37 billion in 2025, at a CAGR of 12.5% during the forecast period.
Browse 300 market data Tables and 50 Figures spread through 300 Pages and in-depth TOC on "Patient Derived Xenografts/PDX Models Market by Type (Mouse, Rat), Service (Model Creation, Characterization), Implantation Method (Subcutaneous), Tumor Type (Respiratory, GI, Gynecological), Application (Preclinical, Biomarker) - Global Forecast to 2030"
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The patient-derived xenograft (PDX) model market is driven by the growing demand for personalized medicine, rising investments in cancer research, and continuous technological advancements in PDX model development. The increasing prevalence of cancer and the need for predictive, patient-relevant preclinical systems are driving the adoption of these systems across the pharmaceutical, biotechnology, and academic sectors, enabling more precise drug discovery, biomarker validation, and translational oncology research.
The mouse model segment is expected to record the highest growth rate during the forecast period
By type, the PDX model market is segmented into mouse models and rat models. The mouse model segment is expected to witness the highest growth rate during the forecast period, driven by its genetic similarity to humans, well-established immune-deficient strains, and proven reliability in replicating human tumor biology. Mouse PDX models provide high tumor engraftment efficiency, reproducible tumor growth patterns, and compatibility with a wide range of cancer types, making them indispensable for preclinical drug evaluation and biomarker discovery. Their widespread use in oncology research, pharmacokinetic studies, and the development of personalized medicine further accelerates their demand. Ongoing advancements in humanized and immuno-oncology mouse models are also enhancing translational accuracy, positioning the mouse models segment as a critical driver of innovation and growth in the PDX model market.
Subcutaneous implantation is expected to hold the largest share during the forecast period
By implantation method, the patient-derived xenograft (PDX) model market is categorized into subcutaneous implantation, orthotopic implantation, and others. The subcutaneous implantation segment accounted for the largest market share in 2024 and is expected to continue its dominance throughout the forecast period. This can be attributed to its technical ease, higher tumor engraftment success rate, cost-effectiveness, and reproducibility, making it a preferred choice among researchers and pharmaceutical companies for preclinical oncology studies. Subcutaneous implantation enables non-invasive tumor monitoring, facilitates rapid evaluation of drug efficacy, and supports high-throughput screening of anticancer compounds. Additionally, continuous advancements in animal model standardization and engraftment optimization have enhanced the consistency of results and their translational relevance. These factors collectively reinforce the adoption of subcutaneous implantation in drug discovery and development, solidifying its position as the leading implantation method in the PDX models market.
Asia Pacific to be the fastest-growing region during the forecast period
The Asia Pacific PDX model market is projected to witness the fastest growth during the forecast period, driven by the rising burden of cancer, expanding pharmaceutical and biotechnology research activities, and increasing emphasis on precision oncology. Strong government support for biomedical research, coupled with growing investments in translational and preclinical infrastructure, is further accelerating market development. Additionally, the availability of cost-effective research capabilities and skilled scientific expertise positions the Asia Pacific as a key hub for PDX-based drug discovery and personalized oncology research.
Key players in the PDX model market include JSR Corporation (Japan), WuXi AppTec (China), The Jackson Laboratory (US), Charles River Laboratories (US), Taconic Biosciences, Inc. (US), Oncodesign Precision Medicine (France), Inotiv (US), Pharmatest Services (Finland), and Hera Biolabs (US), among others.
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