Humanized Mouse and Rat Model Companies

The global humanized mouse and rat model market is projected to reach USD 409.8 million in 2030 from USD 276.2 million in 2025, with a significant CAGR of 8.2% during the forecast period. The market is expanding due to the rising use of humanized models in drug discovery research, emerging preclinical applications of humanized mouse models, government-funded initiatives for cancer research, and increasing R&D activities in the pharmaceutical & biotechnology industry. However, the high cost of custom humanized models and regulatory compliance for the ethical use of animal models are expected to restrain market growth during the forecast period.

Some of the major players in the humanized mouse and rat model market with significant global presence include The Jackson Laboratory (US), Charles River Laboratories (US), Inotiv (US), and genOway (US). To increase their global presence and gain a larger portion of the humanized mouse and rat models market, these companies have implemented numerous organic and inorganic growth tactics, such as partnerships, agreements, expansions, acquisitions, collaborations, and service launches. By providing innovative humanized mice & rat models, these organic and inorganic strategies have enabled market participants to grow internationally.

To know about the assumptions considered for the study download the pdf brochure

For instance, in May 2024, The Jackson Laboratory (JAX) announced a strategic partnership with AbTherx (US), an innovator in biotechnology, to develop and commercialize cutting-edge tools to expedite antibody discovery and development of vital new therapies.

The Jackson Laboratory (JAX) (US) is a leading player in the humanized mouse and rat model market. The company has a prominent presence across North America, Europe, and Asia Pacific. The company has built a diverse range of humanized mouse and rat models, strategically focusing on maintaining the existing customer/end-user base and strengthening long-term contracts. It further leverages its position in the ancillary markets, such as drug discovery and disease modeling, to sustain its market position and broaden offerings around the humanized mouse and rat model market.

Charles River Laboratories (US) is a global drug discovery service CRO that provides a comprehensive portfolio of drug discovery and early-stage development products and services. It has made several acquisitions, partnerships, and cooperation deals. For example, in January 2023, the company acquired SAMDI Tech, which provides label HTS solutions for drug discovery research. In January 2025, it signed a partnership deal with NJ Bio, a CRO providing integrated chemistry and bioconjugation services for developing antibody-drug conjugate (ADC) from concept to clinic. The strategic alliance combines Charles River’s end-to-end ADC discovery services with NJ Bio’s bioconjugation and manufacturing capabilities.

Inotiv (US) is one of the leading market players in the mice model market. The company’s strength can be attributed to its robust product portfolio and numerous acquisitions & partnerships that allow it to market its products worldwide. Inotiv also has a significant geographical footprint in developed countries across North America and Europe. The company’s revenue grew to USD 490.7 million during the fiscal year 2024 from USD 347.8 million during the fiscal year 2021.

genOway (France) is a pioneering biotechnology company located in France and is recognized for its capabilities in developing genetically engineered mouse and rat models for biomedical research. genOway’s commitment to innovation and quality has made it an attractive partner for pharmaceutical companies, biotechnology companies, and academic centers globally.

Market Ranking

The humanized mouse and rat model market is highly consolidated, with four main players collectively holding 53–57% of the total market share. The Jackson Laboratory (JAX) (US) holds a leading position, showcasing its broad influence through a diverse portfolio of products, followed by Charles River Laboratories (US), Inotiv (US), and genOway (France).

Other regional and emerging players share the other 43–47% of the market, resulting in enormous consolidation. Competition in the market is based on a combination of technological advances, product innovation, strategic cooperation, and increased demand from pharmaceutical and biopharmaceutical companies.

Related Reports:

Humanized Mouse and Rat Model Market by Type (Genetic Models, Cell-based Models, Rat Models), Application (Oncology, Immunology, Neuroscience, Toxicology, Infectious Diseases), End User (Pharma, Biotech), and Region - Global Forecast to 2030

Contact:
Mr. Rohan Salgarkar
MarketsandMarkets™ INC.
1615 South Congress Ave.
Suite 103, Delray Beach, FL 33445
USA : 1-888-600-6441
sales@marketsandmarkets.com