HOME Top Market Reports Humanized Mouse and Rat Model Market by Type (Genetic, Cell-Based (CD34, PBMC, BLT)), Application (Neuroscience, Hematopoesis, Oncology, Immunology & Infectious Diseases) & End User (Pharmaceutical & Biotechnology Companies, CRO)) - Global Forecast to 2022

Humanized Mouse and Rat Model Market by Type (Genetic, Cell-Based (CD34, PBMC, BLT)), Application (Neuroscience, Hematopoesis, Oncology, Immunology & Infectious Diseases) & End User (Pharmaceutical & Biotechnology Companies, CRO)) - Global Forecast to 2022

By: marketsandmarkets.com
Publishing Date: March 2018
Report Code: BT 4938

 

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The humanized mouse models market is projected to reach USD 128.9 Million by 2022 from USD 73.9 Million in 2016, at a CAGR of 9.9% during the forecast period. The humanized rat models market is expected to reach USD 8.9 Million by 2022 from USD 5.6 Million in 2016, at a CAGR of 8.4% during the forecast period. The key factors propelling the growth of the market are the increasing number of research activities involving humanized models, growing demand for personalized medicine, increasing number of R&D activities in pharmaceutical and biotechnology companies, and continuous support in the form of investments and grants from the government and private sectors. Increased production of monoclonal antibodies and rising demand for humanized rat models are expected to provide a wide range of growth opportunities for players in the market. Base year considered for the report is 2016 and the forecast period is 2017–2022.

Objectives of the Study:

  • To define, describe, and forecast the global humanized mouse and rat models market on the basis of type, application, end user, and region
  • To provide detailed information regarding the major factors influencing the growth of the market (drivers, restraints, opportunities, and industry-specific challenges)
  • To analyze micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
  • To forecast the size of market segments with respect to four regions, namely, North America, Europe, Asia Pacific, and the Rest of the World (RoW)
  • To analyze opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
  • To analyze the market structure, profile key players of the market, and comprehensively analyze their core competencies
  • To track and analyze competitive developments such as new product launches; partnerships, agreements, and collaborations; expansions; and acquisitions in the global humanized mouse and rat models market

Research Methodology

Top-down and bottom-up approaches were used to validate the size of the global humanized mouse and rat models market and estimate the size of other dependent submarkets. Various secondary sources such World Health Organization (WHO), Centers for Disease Control and Prevention (CDC), International Mouse Phenotyping Consortium (IMPC), Association of Assessment and Accreditation of Laboratory Animal Care (AAALAC), American Association for Laboratory Animal Science (AALAS), Asian Mouse Mutagenesis Resource Association, Pharmaceutical Research and Manufacturers of America, directories, industry journals, databases, and annual reports of the companies have been used to identify and collect information useful for the study of this market. Primary sources such as experts from both supply and demand sides have been interviewed to obtain and validate information as well as to assess dynamics of this market. The breakdown of profiles of primaries is shown in the figure below:

Humanized Mouse and Rat Model Market

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The prominent players in the global humanized mouse and rat models market are The Jackson Laboratory (US), Taconic Biosciences, Inc. (US), and Horizon Discovery Group plc (UK).

Target Audience:

  • Suppliers and distributors of humanized mouse and rat models
  • Research institutes
  • Vendors/service providers

Scope of the Report:

The research report categorizes the humanized mouse and rat models market into the following segments and subsegments:

Humanized Mouse and Rat Model Market, By Type

  • Humanized Mouse Models
    • Genetic Humanized Mouse Models
    • Cell-based Humanized Mouse Models
      • CD34 Humanized Mouse Models
      • PBMC Humanized Mouse Models
      • BLT Humanized Mouse Models
  • Humanized Rat Models

Humanized Mouse and Rat Model Market, By Application

  • Oncology
  • Immunology and Infectious Diseases
  • Neuroscience
  • Toxicology
  • Hematopoiesis
  • Other Applications

Humanized Mouse and Rat Model Market, By End User

  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organizations
  • Academic & Research Institutions

Humanized Mouse and Rat Model Market, By Region

  • North America
    • US
    • Canada
  • Europe
    • EU5
    • Rest of Europe (RoE)
  • APAC
  • Rest of the World

Available Customizations

With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for the report:

Company Information

  • Detailed analysis and profiling of additional market players (Up to 5)

Table of Contents

1 Introduction (Page No. - 17)
    1.1 Objectives of the Study
    1.2 Market Definition
    1.3 Market Scope
           1.3.1 Markets Covered
           1.3.2 Years Considered for the Study
    1.4 Currency
    1.5 Limitations
    1.6 Stakeholders

2 Research Methodology (Page No. - 21)
    2.1 Research Data
           2.1.1 Secondary Data
                    2.1.1.1 Key Data From Secondary Sources
           2.1.2 Primary Data
                    2.1.2.1 Key Data From Primary Sources
                    2.1.2.2 Key Industry Insights
    2.2 Market Size Estimation Methodology
    2.3 Market Breakdown and Data Triangulation
    2.4 Assumptions for the Study

3 Executive Summary (Page No. - 32)

4 Premium Insights (Page No. - 37)
    4.1 Humanized Mouse Models: Market Overview
    4.2 Humanized Rat Models: Market Overview
    4.3 Rat Model Market Share, By Region and End User (2017)
    4.4 Humanized Mouse Models Market, By Type, 2017 vs 2022
    4.5 Geographic Snapshot of the Humanized Mouse Models Market

5 Market Overview (Page No. - 41)
    5.1 Introduction
    5.2 Market Dynamics
           5.2.1 Drivers
                    5.2.1.1 Increasing Number of Research Activities Involving Humanized Models
                               5.2.1.1.1 Mouse Models for Immunodeficiency Disorders
                               5.2.1.1.2 Humanized Models for Cancer
                               5.2.1.1.3 Mouse Models for Rare Diseases and Graft-Versus-Host Disease
                    5.2.1.2 Growing Demand for Personalized Medicine
                    5.2.1.3 Continuous Support in the Form of Investments and Grants From the Government and Private Sectors
                               5.2.1.3.1 Funding/Grants By the National Institutes of Health (NIH)
                               5.2.1.3.2 Funding/Grants Received From Other Government Bodies
                    5.2.1.4 Increasing Number of R&D Activities in Pharmaceutical and Biotechnology Companies
           5.2.2 Restraints
                    5.2.2.1 High Cost of Humanized Models
                    5.2.2.2 Regulations & Laws Formulated for Ethical Use of Animals
                               5.2.2.2.1 The Animal Welfare Act (AWA)
                               5.2.2.2.2 Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals
           5.2.3 Opportunities
                    5.2.3.1 Increased Production of Monoclonal Antibodies
                    5.2.3.2 Rising Demand for Humanized Rat Models
           5.2.4 Challenges
                    5.2.4.1 Advances in Zebrafish Model Development
                    5.2.4.2 Alternative Methods of Animal Testing
                    5.2.4.3 Limitations of Humanized Mouse Models

6 Clinical Trails & Research Studies Assessment (Page No. - 51)
    6.1 Introduction
    6.2 Clinical Trials
    6.3 Research Studies

7 Humanized Mouse and Rat Models Market, By Type (Page No. - 58)
    7.1 Introduction
    7.2 Humanized Mouse Models
           7.2.1 Genetic Humanized Mouse Models
           7.2.2 Cell-Based Humanized Mouse Models
                    7.2.2.1 CD34 Humanized Mouse Models (HU-CD34)
                    7.2.2.2 PBMC Humanized Mouse Models
                    7.2.2.3 BLT Humanized Mouse Models
    7.3 Humanized Rat Models

8 Humanized Mouse Models Market, By Application (Page No. - 71)
    8.1 Introduction
    8.2 Oncology
           8.2.1 Key Developments By Industry Players to Strengthen Cancer Research
           8.2.2 Continuous Grants/Funds to Support Cancer Research Studies
    8.3 Immunology and Infectious Diseases
           8.3.1 Grants/Funds for Immunology and Infectious Diseases Research
    8.4 Neuroscience
           8.4.1 Grants/Funds for Neurological Research
    8.5 Toxicology
    8.6 Hematopoiesis
    8.7 Other Applications
           8.7.1 Increasing Funding for Rare Diseases, Graft-Vs-Host Diseases, and Cardiovascular Disease Research

9 Humanized Mouse Models Market, By End User (Page No. - 86)
    9.1 Introduction
    9.2 Pharmaceutical & Biotechnology Companies
    9.3 Contract Research Organizations
    9.4 Academic & Research Institutions

10 Humanized Mouse Models Market, By Region (Page No. - 94)
     10.1 Introduction
     10.2 North America
             10.2.1 Us
                        10.2.1.1 Availability of Support for Research in the Us
                        10.2.1.2 Growing Focus of Oncology Research in the Us
                        10.2.1.3 Conferences and Other Events Contributing to the Spread of Innovation and Awareness
                        10.2.1.4 Growing Production of Monoclonal Antibodies
                        10.2.1.5 Development of Biosimilars Boosting the Demand for Preclinical Services
             10.2.2 Canada
                        10.2.2.1 Growing Stem Cell Research in Canada
                        10.2.2.2 Government Support for the Development of Protein Drugs
     10.3 Europe
             10.3.1 EU5
                        10.3.1.1 Germany: Flourishing Biotechnology Industry
                        10.3.1.2 UK: Emphasis on Quality Research Results and Increase in Cell Therapy Preclinical Research
                        10.3.1.3 France: Funding for Rare Disease Projects
                        10.3.1.4 Italy: Growth in the Biotechnology and Pharmaceutical Sector
                        10.3.1.5 Spain: Availability of VC Funding for Life Sciences
             10.3.2 Rest of Europe (RoE)
                        10.3.2.1 Growing Investments in Research By Sweden & Denmark
                        10.3.2.2 Focus on Rare Disease Research Projects
     10.4 Asia Pacific
             10.4.1 China: Strong Research Expenditure, Well-Structured CRO Industry
             10.4.2 Rising Focus on Personalized Medicine in China
             10.4.3 Increasing Public & Private Investments in China’s Life Sciences Sector
             10.4.4 Initiatives to Reduce Long Approval Times in China
             10.4.5 Japan: Growth in Biomedical & Medical Research
             10.4.6 Research Into Regenerative Medicine in Japan
             10.4.7 Growth of the Pharmaceutical Industry in India
             10.4.8 Development of Bioclusters to Boost India’s Biotechnology Sector
             10.4.9 Infrastructural Limitations in India, A Key Hindrance to Market Growth
             10.4.10 Biomedical Research in Australia
             10.4.11 Growth in Translational & Biomedical Research in Singapore
             10.4.12 Increase in Animal Research in Malaysia
             10.4.13 Rising Pharmaceutical & Biotechnology R&D Activities in South Korea
     10.5 Rest of the World
             10.5.1 Brazil: Growth in the Pharmaceutical, Biotechnology, and Research Industries
             10.5.2 Favorable Business Environment for the Pharmaceutical & Biotechnology Industries in Saudi Arabia & the UAE
             10.5.3 Increasing Investments in Mexico

11 Competitive Landscape (Page No. - 136)
     11.1 Overview
     11.2 Market Share Analysis
             11.2.1 Introduction
             11.2.2 Cell-Based Humanized Mouse Model Market
                        11.2.2.1 The Jackson Laboratory (US)
                        11.2.2.2 Taconic Biosciences (US)
             11.2.3 Genetic Humanized Mouse Model Market
                        11.2.3.1 Horizon Discovery Group (UK)
                        11.2.3.2 Taconic Biosciences (US)
     11.3 Competitive Scenario
             11.3.1 Agreements, Partnerships, and Collaborations
             11.3.2 Grants/Funds
             11.3.3 Product Launches
             11.3.4 Acquisitions
             11.3.5 Expansions
             11.3.6 Other Strategies

12 Company Profiles (Page No. - 145)
(Overview, Strength of Product Portfolio, Business Strategy Excellence, Products Offering, and Recent Developments)*
     12.1 The Jackson Laboratory
     12.2 Taconic Biosciences
     12.3 Crown Bioscience (Subsidiary of Jsr Corporation)
     12.4 Champions Oncology
     12.5 Horizon Discovery (Sage Labs)
     12.6 Hera Biolabs
     12.7 Genoway
     12.8 Vitalstar Biotechnology
     12.9 Ingenious Targeting Laboratory
     12.10 Axenis
     12.11 Trans Genic
     12.12 Harbour Antibodies (A Subsidiary of Harbour Biomed)
     12.13 Charles River Laboratories

*Details on Overview, Strength of Product Portfolio, Business Strategy Excellence, Products Offering, and Recent Developments Might Not Be Captured in Case of Unlisted Companies.

13 Appendix (Page No. - 180)
     13.1 Discussion Guide
     13.2 Knowledge Store: Marketsandmarkets’ Subscription Portal
     13.3 Introducing RT: Real-Time Market Intelligence
     13.4 Available Customizations
     13.5 Related Reports
     13.6 Author Details


List of Tables (94 Tables)

Table 1 Sampling Frame: Primary Research
Table 2 Indicative List of Clinical Trails Conducted on Humanized Mice Models
Table 3 Indicative List of Research Studies Conducted on Humanized Mice Models
Table 4 Rat Model Models Market, By Type, 2015–2022 (USD Million)
Table 5 Genetic Humanized Mouse Models Market, By Region, 2015–2022 (USD Million)
Table 6 North America: Genetic Rat Model Market, By Country, 2015–2022 (USD Million)
Table 7 Europe: Genetic Rat Model Market, By Region, 2015–2022 (USD Million)
Table 8 Cell-Based Rat Model Market, By Type, 2015–2022 (USD Million)
Table 9 Cell-Based Rat Model Market, By Region, 2015–2022 (USD Million)
Table 10 North America: Cell-Based Humanized Mouse Models Market, By Country, 2015–2022 (USD Million)
Table 11 Europe: Cell-Based Rat Model Market, By Region, 2015–2022 (USD Million)
Table 12 CD34 Rat Model Market, By Region, 2015–2022 (USD Million)
Table 13 North America: CD34 Rat Model Market, By Country, 2015–2022 (USD Million)
Table 14 Europe: CD34 Humanized Mouse Models Market, By Region, 2015–2022 (USD Million)
Table 15 PBMC Rat Model Market, By Region, 2015–2022 (USD Million)
Table 16 North America: PBMC Rat Model Market, By Country, 2015–2022 (USD Million)
Table 17 Europe: PBMC Rat Model Market, By Region, 2015–2022 (USD Thousand)
Table 18 BLT Humanized Mouse Models Market, By Region, 2015–2022 (USD Thousand)
Table 19 North America: BLT Humanized Mouse Models Market, By Country, 2015–2022 (USD Thousand)
Table 20 Europe: BLT Rat Model Market, By Region, 2015–2022 (USD Thousand)
Table 21 Rat Model Market, By Application, 2015–2022 (USD Million)
Table 22 Indicative List of Recent Cancer Research Studies Using Humanized Mouse Models
Table 23 Rat Model Market for Oncology, By Region, 2015–2022 (USD Million)
Table 24 North America: Rat Model Market for Oncology, By Country, 2015–2022 (USD Million)
Table 25 Europe: Rat Model Market for Oncology, By Region, 2015–2022 (USD Million)
Table 26 Rat Model Market for Immunology and Infectious Diseases, By Region, 2015–2022 (USD Million)
Table 27 North America: Rat Model Market for Immunology and Infectious Diseases, By Country, 2015–2022 (USD Million)
Table 28 Europe: Rat Model Market for Immunology and Infectious Diseases, By Region, 2015–2022 (USD Million)
Table 29 Rat Model Market for Neuroscience, By Region, 2015–2022 (USD Million)
Table 30 North America: Rat Model Market for Neuroscience, By Country, 2015–2022 (USD Million)
Table 31 Europe: Rat Model Market for Neuroscience, By Region, 2015–2022 (USD Million)
Table 32 Rat Model Market for Toxicology, By Region, 2015–2022 (USD Million)
Table 33 North America: Rat Model Market for Toxicology, By Country, 2015–2022 (USD Million)
Table 34 Europe: Rat Model Market for Toxicology, By Region, 2015–2022 (USD Million)
Table 35 Rat Model Market for Hematopoiesis, By Region, 2015-2022 (USD Million)
Table 36 North America: Rat Model Market for Hematopoiesis, By Country, 2015–2022 (USD Million)
Table 37 Europe: Rat Model Market for Hematopoiesis, By Region, 2015–2022 (USD Million)
Table 38 Rat Model Market for Other Applications, By Region, 2015-2022 (USD Million)
Table 39 North America: Rat Model Market for Other Applications, By Country, 2015–2022 (USD Million)
Table 40 Europe: Rat Model Market for Other Applications, By Region, 2015–2022 (USD Million)
Table 41 Rat Model Market, By End User, 2015–2022 (USD Million)
Table 42 Rat Model Market for Pharmaceutical & Biotechnology Companies, By Region, 2015–2022 (USD Million)
Table 43 North America: Rat Model Market for Pharmaceutical & Biotechnology Companies, By Country, 2015–2022 (USD Million)
Table 44 Europe: Rat Model Market for Pharmaceutical & Biotechnology Companies, By Region, 2015–2022 (USD Million)
Table 45 Rat Model Market for Contract Research Organizations, By Region, 2015–2022 (USD Million)
Table 46 North America: Rat Model Market for Contract Research Organizations, By Country, 2015–2022 (USD Million)
Table 47 Europe: Humanized Mouse Models Market for Contract Research Organizations, By Region, 2015–2022 (USD Million)
Table 48 Humanized Mouse Models Market for Academic & Research Institutions, By Region, 2015–2022 (USD Million)
Table 49 North America: Humanized Mouse Models Market for Academic & Research Institutions, By Country, 2015–2022 (USD Million)
Table 50 Europe: Humanized Mouse Models Market for Academic & Research Institutions, By Country, 2015–2022 (USD Million)
Table 51 Humanized Mouse Models Market, By Region, 2015–2022 (USD Million)
Table 52 North America: Humanized Mouse Models Market, By Country, 2015–2022 (USD Million)
Table 53 North America: Rat Model Market, By Type, 2015–2022 (USD Million)
Table 54 North America: Cell-Based Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 55 North America: Rat ModelMarket, By Application, 2015–2022 (USD Million)
Table 56 North America: Rat Model Market, By End User, 2015–2022 (USD Million)
Table 57 NIH Funding for Projects Related to Animal Models
Table 58 Recent Events Related to the Animal Models Market
Table 59 US: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 60 US: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Million)
Table 61 US: Humanized Mouse Models Market, By Application, 2015–2022 (USD Million)
Table 62 US: Rat Model Market, By End User, 2015–2022 (USD Million)
Table 63 Canada: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 64 Canada: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Thousand)
Table 65 Canada: Rat Model Market, By Application, 2015–2022 (USD Thousand)
Table 66 Canada: Humanized Mouse Models Market, By End User, 2015–2022 (USD Million)
Table 67 Europe: Rat Model Market, By Region, 2015–2022 (USD Million)
Table 68 Europe: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 69 Europe: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Million)
Table 70 Europe: Humanized Mouse Models Market, By Application, 2015–2022 (USD Million)
Table 71 Europe: Rat Model Market, By End User, 2015–2022 (USD Million)
Table 72 EU5: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 73 EU5: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Million)
Table 74 EU5: Humanized Mouse Models Market, By Application, 2015–2022 (USD Million)
Table 75 EU5: Rat Model Market, By End User, 2015–2022 (USD Million)
Table 76 RoE: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 77 RoE: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Million)
Table 78 RoE: Humanized Mouse Models Market, By Application, 2015–2022 (USD Thousand)
Table 79 RoE: Rat Model Market, By End User, 2015–2022 (USD Million)
Table 80 Japan: Significant Partnerships
Table 81 Asia Pacific: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 82 Asia Pacific: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Thousand)
Table 83 Asia Pacific: Humanized Mouse Models Market, By Application, 2015–2022 (USD Million)
Table 84 Asia Pacific: Rat Model Market, By End User, 2015–2022 (USD Million)
Table 85 RoW: Humanized Mouse Models Market, By Type, 2015–2022 (USD Million)
Table 86 RoW: Cell-Based Rat Model Market, By Type, 2015–2022 (USD Thousand)
Table 87 RoW: Humanized Mouse Models Market, By Application, 2015–2022 (USD Thousand)
Table 88 RoW: Rat Model Market, By End User, 2015–2022 (USD Thousand)
Table 89 Agreements, Partnerships, and Collaborations 2015–2018
Table 90 Grant/Fund, 2015–2018
Table 91 Product Launches, 2015–2018
Table 92 Acquisitions, 2015–2018
Table 93 Expansions, 2015–2018
Table 94 Other Strategies, 2015–2018


List of Figures (42 Figures)

Figure 1 Research Methodology: Global Humanized Mouse and Rat Models Market
Figure 2 Research Design: Global Humanized Mouse and Rat Models Market
Figure 3 Breakdown of Primary Interviews: By Company Type, Designation, and Region
Figure 4 Market Size Estimation Methodology: Bottom-Up Approach
Figure 5 Market Size Estimation Methodology: Top-Down Approach
Figure 6 Data Triangulation Methodology
Figure 7 Humanized Mouse Models Market, By Application (2017)
Figure 8 Rat Model Market, By Type, 2017 vs 2022
Figure 9 Cell-Based Humanized Mouse Models Market, By Type, 2017 vs 2022
Figure 10 Rat Model Market, By End User, 2017 vs 2022
Figure 11 Humanized Rat Models Market Overview
Figure 12 The Humanized Mouse Models Market in Asia Pacific to Witness the Highest Growth During the Forecast Period
Figure 13 Increasing Number of Research Activities Involving Humanized Mouse Models, A Major Factor Driving the Growth of the Market
Figure 14 Growing Demand for Personalized Medicine, A Major Factor Driving the Growth of the Humanized Rat Models Market
Figure 15 Pharmaceutical & Biotechnology Companies Accounted for the Largest Share of the Market in 2017
Figure 16 Genetic Humanized Mouse Models to Continue to Dominate the Humanized Mouse Models Market in 2022
Figure 17 Asia Pacific to Register the Highest CAGR During the Forecast Period
Figure 18 Drivers, Restraints, Opportunities, and Challenges
Figure 19 US: Clinical Trials Using Humanized Mice Models, By Indication (2013–2023)
Figure 20 US: Clinical Trials Using Humanized Mice Models, By Completion (2013–2023)
Figure 21 US: Clinical Trials Using Humanized Mice Models, By Phase (2013–2023)
Figure 22 US: Research Studies Using Humanized Mice Models, By Indication (2013–2023)
Figure 23 Genetic Humanized Mouse Models to Dominate the Market in 2017
Figure 24 CD34 Humanized Mouse Models Segment to Grow at the Highest CAGR During the Forecast Period
Figure 25 Humanized Rat Models Market, 2015–2022 (USD Million)
Figure 26 Oncology Segment Accounted for Largest Share of the Humanized Mouse Models Market in 2017
Figure 27 Pharmaceutical & Biotechnology Companies to Dominate the Humanized Mouse Models Market in 2017
Figure 28 North America Will Continue to Dominate the Humanized Mouse Models Market in 2022
Figure 29 North America: Humanized Mouse Models Market Snapshot
Figure 30 Europe: Humanized Mouse Models Market Snapshot
Figure 31 Cell Therapy Preclinical Studies in the UK, 2013–2016
Figure 32 Asia Pacific: Humanized Mouse Models Market Snapshot
Figure 33 RoW: Humanized Mouse Models Market Snapshot
Figure 34 Key Developments in the Humanized Mouse Model Market, 2015–2018
Figure 35 Market Share Analysis for Cell-Based Humanized Mouse Model, By Key Players, 2016
Figure 36 Market Share Analysis for Genetic Humanized Mouse Model, By Key Player, 2016
Figure 37 The Jackson Laboratory: Company Snapshot (2016)
Figure 38 Champions Oncology: Company Snapshot (2016)
Figure 39 Horizon Discovery: Company Snapshot (2016)
Figure 40 Genoway: Company Snapshot (2017)
Figure 41 Trans Genic: Company Snapshot (2016)
Figure 42 Charles River Laboratories: Company Snapshot (2016)

The humanized mouse models market is projected to reach USD 128.9 Million by 2022 from USD 80.3 Million in 2017, at a CAGR of 9.9% during the forecast period. The humanized rat models market is expected to reach USD 8.9 Million by 2022 from USD 5.9 Million in 2017, at a CAGR of 8.4% during the forecast period. The key factors boosting market growth are increasing number of R&D activities in pharmaceutical and biotechnology companies, increasing number of research activities involving humanized models, continuous support in the form of investments and grants from the government and private sectors, and growing demand for personalized medicine.

By type, the humanized mouse models market is segmented into genetic and cell-based humanized mouse models. In 2017, the genetic models segment accounted for the largest share of the humanized mouse models market. The factors contributing to the large share of this segment include its widespread use in compound analysis and biological efficacy & safety testing. Furthermore, the cell-based humanized mouse models is categorized into CD34, PBMC, and BLT humanized mouse models. In 2017, the CD34 models segment accounted for the largest share of the cell-based humanized mouse models market and is expected to register the highest growth rate during the forecast period. The major factors driving the growth of this market are usage of CD34 mouse models in in-vivo platforms for analyzing the safety and effectiveness of potential new drugs that can modulate the immune system. They are used for long-term studies in the fields of immuno-oncology, infectious disease, and graft versus host disease. Thus, the growing application areas of CD34 models are expected to trigger the demand for these models in the coming years.

By application, the humanized mouse models market is segmented into oncology, immunology and infectious diseases, neuroscience, hematopoiesis, toxicology, and other applications. The oncology segment is estimated to grow at the highest CAGR owing to factors such as increasing research activities and growing funding from various governments to carry out research studies on cancer.

By end user, the humanized mouse models market is segmented into pharmaceutical & biotechnology companies, contract research organizations (CROs), and academic & research institutions. The pharmaceutical & biotechnology companies segment accounted for the largest share of the humanized mouse models market in 2017. However, the contract research organizations (CROs) segment of the market is projected to grow at the highest CAGR during the forecast period. Increasing number of pharmaceutical companies outsourcing their preclinical studies to contract research organizations (CROs) is one of the factors contributing to the growth of this segment.

Humanized Mouse and Rat Model Market

By region, the humanized mouse models market is segmented as North America, Europe, Asia Pacific, and RoW. Asia Pacific is expected to grow at the highest CAGR owing to international alliances for R&D activities in China, initiatives to reduce approval time for drugs, mandatory animal testing for all pharmaceutical drugs and cosmetics in China, increasing investments from the government and private sectors in China’s life sciences sector, growing biomedical and medical research, and research in regenerative medicine in Japan. Furthermore, the growth of the biomedical industry in India, development of bio-clusters to boost India’s biotechnology, growth in translational and biomedical research in Singapore, increase in animal research in Malaysia, and ongoing biomedical research activities in Australia are also driving the growth of the market in Asia Pacific.

Factors such as high cost of humanized models and stringent guidelines regarding the ethical use of animals in cancer research are expected to limit the growth of the market to a certain extent.

The major market players in the humanized mouse models market include The Jackson Laboratory (US), Taconic Biosciences, Inc. (US), Horizon Discovery Group plc (UK), genOway, S.A. (France), Charles River Laboratories (US), Harbour Antibodies BV (China), Hera BioLabs (US), Vitalstar Biotechnology Co., Ltd. (China), inGenious Targeting Laboratory (US), AXENIS S.A.S (France), Crown Bioscience, Inc. (US), Transgenic, Inc. (Japan), and Champions Oncology, Inc. (US). The major players in the humanized rat models market include Horizon Discovery Group plc (UK), Hera BioLabs (US), and Yecuris Corporation (US).

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