North America Nucleic Acid Isolation and Purification Market

The North America nucleic acid isolation and purification market is projected to reach USD 4.64 billion by 2030 from USD 2.98 billion in 2025, at a CAGR of 9.3% during the forecast period. Major factors supporting growth in the North America nucleic acid isolation and purification market include strong government and institutional funding for genomics, precision medicine, and life sciences research, which sustains high testing and sequencing volumes across academic and clinical settings.

The North America nucleic acid isolation and purification market is competitive. Prominent players in the market are Thermo Fisher Scientific Inc. (US), QIAGEN (Germany), F. Hoffman-La Roche Ltd. (Switzerland), Danaher Corporation (US), Agilent Technologies, Inc. (US), and Merck KGaA (Germany), among others.

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In July 2023, INOVIQ and Promega Corporation announced a global joint marketing agreement for EXO-NET exosome isolation and nucleic acid purification solutions. In October 2022, Thermo Fisher Scientific Inc. (US) invested USD 97 million in expanding its clinical research operations in Richmond, Virginia. The facility will provide high-quality bioanalytical lab services to advance clinical research programs.

Thermo Fisher Scientific Inc. is one of the major players in the North America nucleic acid isolation and purification market. The company benefits from a broad portfolio that covers magnetic bead-based extraction kits, spin-column kits, and ready-to-use buffers and plastics used in day-to-day DNA/RNA workflows. Its strong position is also supported by a large installed base of KingFisher automated extraction systems, which are widely used in hospital labs, reference labs, and research centers. In recent years, demand has been growing steadily due to high testing volumes in PCR/NAAT and the expanding needs for NGS sample preparation.

QIAGEN is another established player in the North America nucleic acid isolation and purification market. The ompany’s strength is primarily its deep sample preparation portfolio, led by QIAamp and RNeasy kits, which are widely used for routine DNA and RNA extraction. It has strong adoption across hospitals, reference laboratories, public health laboratories, and research institutes, where a consistent yield is crucial. QIAGEN also benefits from its automation footprint through platforms such as QIAsymphony and QIAcube, which help labs standardize their workflows.

F. Hoffmann-La Roche (Roche Diagnostics) is a strong player in the North America nucleic acid isolation and purification market, mainly through its presence in clinical molecular testing. The company benefits from a large installed base of Roche diagnostic platforms in hospitals and reference laboratories, where sample preparation is tightly integrated with routine PCR workflows. Roche’s approach is centered on standardized, regulated, and automation-friendly extraction, which fits labs that need consistent performance and traceability.

Market Ranking

The nucleic acid isolation and purification market in North America is competitive, with major suppliers growing their businesses by utilizing trusted chemistries, strong automation footprints, and recurring demand for consumables.

Thermo Fisher Scientific is a leader, supported by a wide range of magnetic bead and column-based kits, as well as a large installed base of KingFisher systems, which leads to repeat purchases of reagents and plastics. QIAGEN remains a core benchmark player, supported by commonly used DNA/RNA kits and automation platforms that facilitate the standardization of extraction across different labs/sites. Roche Diagnostics is a major player in clinical molecular testing, where buyers prefer regulated, consistent, and workflow-integrated extraction as a way of safeguarding turnaround time and result quality. In fact, across end users, purchasing decisions are more inclined towards high-throughput bead-based workflows, contamination control, documentation support, and scalable automation; thus, kits & consumables remain at the core of competition.

Related Reports:

North America Nucleic Acid Isolation and Purification Market by Product (Kits, Reagents, Instruments), Method (Column, Magnetic Beads), Type (Genomic DNA, Plasmid DNA), Application (Diagnostics, Personalized Medicine), End User (CROs) - Forecast to 2030

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