The protein expression market is expected to reach USD 5.4 million in 2027 from USD 2.9 million in 2022 at a CAGR of 13.3% during the forecast period. Factors such as growing pharmaceutical and biotechnology as well as life-sciences industries, a rise in the focus on recombinant-based protein expression, and the availability of investment for protein-based research. However, the high cost of protein expression reagents and instruments is expected to restrain the growth of this market to a certain extent.
The protein expression market is highly consolidated. The top players in this market hold a significant share of the total market. Prominent market players include Thermo Fisher Scientific Inc. (US), Merck KGaA (Germany), Promega Corporation (US), Agilent Technologies, Inc. (US), Bio-Rad Laboratories, Inc. (US), and Takara Bio Inc. (Japan). These companies offer a wide range of protein expression products as well as services focusing on innovating. However, the high market consolidation acts as a barrier for new entrants in the market
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Thermo Fisher Scientific Inc. (US) is the largest player in the protein expression market. Factors such as strong suite of expression vectors, reagents, competent cells, and instruments, as well as protein expression services are highly attributing to the large share of this company. Owing to its strong sales and distribution network, the company has a significant global footprint. Additionally, presence of multiple production sites at majority geographic locations gives the company an edge over other players in the protein expression market.
The company focuses on collaboration in order to strengthen its position in the market. For instance, in June 2021, Thermo entered into an agreement with Advanced Electrophoresis Solutions Ltd. (AES) (Canada) to advance therapeutic protein development by combining their protein separation techniques. The company further intends to strengthen its presence in this market by investing in R&D. Its extensive R&D activities enable it to increase its depth of capabilities in protein expression solutions and services and to provide innovative products and services in the market space.
Merck KGaA (Germany) is also one of the significant players in the protein expression market. Merck has a broad range of protein expression systems and products, such as mammalian cell expression systems, prokaryotic expression systems, yeast cell expression systems, and insect cell expression systems. The company also offers a variety of expression vectors, reagents, and competent cells for the protein expression market.
Merck continues to analyze and evaluate its global footprint and overall operating model. This is evident from the instance in early 2019, Merck approved a new global Restructuring Program as a part of a worldwide initiative focused on further optimizing the company’s manufacturing and supply network, as well as reducing its global real estate footprint.
Merck uses the strategy of establishing life sciences facilities for R&D to increase its global presence. For instance, in 2020, Merck announced plans to invest USD 282.5 million in the construction of a new biotech development facility in Switzerland. The company also announced plans to establish its sustainability center in Dubai to accelerate research and innovation in the field of science and technology. Furthermore, in July 2020, Merck established a laboratory facility for the production of certified reference materials, analytical standards and reagents, building blocks and bioanalytical reagents for their academia, as well as industrial research and quality control laboratory customers.
Agilent Technologies, Inc. (US) is a leader in providing instruments, software, services, and consumables for laboratory operations. The company has a broad portfolio of protein expression products, such as competent cells, expression vectors, kits for protein purification, and transfection. The biopharma companies and academia highly rely on Agilent for its protein expression products. Besides, in 2021, the company experienced double-digit growth in its revenue from protein expression as compared to 2020. Also, the company continues to invest highly in R&D for its growth. In 2021, the company invested around USD 358 million.
Protein Expression Market by Type (E.Coli, Mammalian, CHO, HEK 293, Insect, Pichia, Cell-free), Products (Reagents, Vectors, Competent Cells, Instruments, Service), Application (Therapeutic, Industrial), End User, and Region - Global Forecast to 2027
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