Leading Companies in Real World Evidence Solutions

The real world evidence solutions market is projected to reach USD 10.8 billion by 2030 from USD 5.42 billion in 2025, at a CAGR of 14.8% during the forecast period. Real world evidence (RWE) solutions use information obtained from real-world settings, including clinical practice, patient experiences, and health outcomes, to derive insights and make well-informed decisions in healthcare. This evidence differs from data gathered in conventional clinical trials, referring to everyday conditions and the large patient population encountered in real-world settings. The increasing geriatric population and the rising incidence of chronic health diseases are key factors driving the growth of the RWE solutions market. In 2023, the research-based pharmaceutical industry in Europe is estimated to have invested approximately USD 55 billion in the R&D process (Source: European Federation of Pharmaceutical Industries and Associations). Additionally, the RWE solution can potentially reduce the cost and time needed for the drug development process; hence, several pharmaceutical, biopharmaceutical, and medical device companies are focusing on the uptake of RWE solutions.

Two dominant strategies are shaping the real world evidence solutions market: product innovation and strategic collaboration. In March 2025, ICON plc (Ireland) launched PatientSourceDuo (real-world data asset). It provides linked healthcare claims data that supports analysis across the patient journey, primarily used in research & commercial evidence strategies. Similarly, in January 2025, IQVIA Holdings Inc. (US) and NVIDIA Corporation (US) collaborated to accelerate the use of AI in healthcare & life sciences. These AI agents are being built to tackle complex, repetitive tasks such as synthesizing literature, reviewing clinical data, finding trial sites, and engaging healthcare professionals. These alliances have broadened service portfolios, improved operational efficiency, and accelerated the adoption of modern RWE solutions across healthcare organizations.

The leading players operating in this market are IQVIA Inc. (US), Merative (US), Optum Inc. (US), ICON Plc (Ireland), Syneos Health (US), Parexel International Corporation (US), Tata Consultancy Services (India), Oracle (US), Elevance Health (US), SAS Institute Inc. (US), Aetion Inc. (US), Trinetx, LLC (US), Trinity (US), Cognizant Technology Solutions Corporation (US), Cegedim Health Data (France), Verantos (US), Medpace Holdings Inc. (US), FLATIRON HEALTH (US), Fortrea (US), and Medidata (US) (subsidiary of Dassault Systèmes).

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IQVIA Inc. (US):

IQVIA Inc. is a prominent global provider of technology solutions, advanced analytics, and clinical research services. The company’s offerings play a crucial role in assisting biotechnology firms, medical device manufacturers, pharmaceutical companies, government agencies, medical researchers, payers, and healthcare stakeholders gain insights into diseases, human behavior, and scientific advancements. The company possesses a vast & varied data infrastructure, granting access to an extensive range of healthcare data, such as electronic health records (EHRs), claims data, and other real-world datasets. This access helps provide insights into patient outcomes, treatment patterns, and healthcare utilization. The company has a base of over 10,000 clients in over 100 countries and is present across North America, Europe, the Asia Pacific, and Africa.

Merative (US):

Formerly known as IBM Watson Health, Merative transitioned into an independent entity under Francisco Partners in 2022. The company is dedicated to assisting clients in reconstructing information and gaining insights into the populations served, ultimately enhancing healthcare delivery, decision-making processes, and overall performance. The company provides real world evidence solutions, such as the Merative MarketScan Research Databases, Merative MarketScan Commercial Database, and the Merative Explorys EHR Database, facilitating comprehensive analyses for its users.

Optum, Inc. (US):

Optum, Inc., a subsidiary of UnitedHealth Group, Inc., is a diverse healthcare organization that helps individuals live healthier lives and improve the efficiency of the healthcare system. The company stands as a diverse healthcare organization with a mission to enhance the well-being of individuals and optimize the efficiency of the healthcare system. Through its Optum Insight segment, the company offers RWE solutions, enabling healthcare systems to effectively manage costs, adhere to compliance requirements, enhance clinical performance, and navigate the dynamic healthcare landscape. These solutions are catered to payers, care providers, employers, governments, life science companies, and consumers. The company operates across 150 countries spanning North America, the Asia Pacific, Europe, Latin America, the Middle East, and Africa.

Related Reports:

Real World Evidence Solutions Market by Component (Datasets (Claims, Clinical, Pharmacy, Genomics), Application (Drug/Device Development (Cancer, Cardio, Neuro), Reimbursement), End User (Pharma, Medtech, Payers, Provider), Region - Global Forecast to 2030

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