Nucleic Acid Isolation and Purification Market

The global nucleic acid isolation and purification market is expected to grow from USD 7.10 billion in 2025 to USD 10.99 billion in 2030, at a CAGR of 9.1% during the forecast period.

The global market for nucleic acid isolation and purification (NAIP) has been significantly influenced by several factors. Among these, increased government and institutional funding for genomics, precision medicine, and life sciences research across major regions stand out. This financial support is instrumental in expanding laboratory capacity, modernizing workflows, and maintaining routine PCR/NAAT and sequencing volumes in both academic and clinical settings.

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This market is competitive, with key players such as Thermo Fisher Scientific Inc. (US), Qiagen (Germany), F. Hoffman-La Roche Ltd. (Switzerland), Danaher Corporation (US), Agilent Technologies, Inc. (US), and Merck KGaA (Germany), among others. These players have implemented organic and inorganic growth strategies to strengthen their position in the nucleic acid isolation and purification (NAIP) market.

Advancements in bioinformatics and data analytics are having a ripple effect across the global nucleic acid isolation and purification (NAIP) market. The processing and interpretation of sequencing data have become so straightforward that NGS workflows are being adopted in more labs across research and clinical settings. The decreasing costs of sequencing are also broadening the number of use cases, thereby increasing routine demand for clean, inhibitor-free DNA/RNA as a front-end step. Precision medicine, genome research, and population genomics programs are growing in several regions, keeping sample volumes high.

In July 2023, INOVIQ and Promega Corporation announced a global joint marketing agreement for EXO-NET exosome isolation and nucleic acid purification solutions. In October 2022, Thermo Fisher Scientific Inc. (US) invested USD 97 million to expand its clinical research operations in Richmond, Virginia. The facility will provide high-quality bioanalytical lab services to advance clinical research programs.

Thermo Fisher Scientific Inc. (US)

Thermo Fisher is a major player in nucleic acid isolation and purification. The company's clients include clinical labs, reference labs, biopharma, and research institutes. It offers a mix of magnetic bead and spin column extraction kits. In addition, it provides popular automation platforms that support routine, high-volume DNA/RNA prep. The firm enjoys a high pull-through effect, as instrument placements often lead to repeat purchases of kits, buffers, plastics, and consumables. Thermo Fisher is well positioned in rapidly expanding workflows such as infectious disease testing, oncology profiling, NGS sample prep, and liquid biopsy/cfDNA, where yield and inhibitor removal are important. Thermo Fisher also offers lab standardization through validated, workflow-ready formats that help lower variability across operators and sites. In conclusion, its end-to-end portfolio and global distribution are key reasons for the company's strategic position in the market.

 
QIAGEN (US)

QIAGEN is a leading player in the global nucleic acid isolation and purification market. Its products are widely used in clinical diagnostics, public health labs, and research environments. The company is best known for its spin column kits and chemistries, which deliver reliable DNA/RNA purity. This keeps it embedded in routine PCR and sequencing workflows. The company has also positioned itself strongly in automation, supporting higher-throughput extraction for laboratories that demand speed, traceability, and repeatability at scale. QIAGEN enjoys a robust consumables portfolio advantage, as daily extraction volumes are the main drivers of recurring purchases of kits, reagents, and plastics. It is also well-positioned in the growth sectors of infectious disease testing, oncology, and genetic screening.

F. Hoffman-La Roche Ltd. (Switzerland)

Roche is a leading global player in nucleic acid isolation and purification, driven largely by its scale in molecular diagnostics and its deep presence in hospital and reference lab networks. The company benefits from an integrated approach in which sample preparation is a critical front-end step for reliable PCR and NAAT testing. Roche's strength is most evident in high-volume clinical workflows, especially infectious disease testing and other routine molecular assays where labs prioritize standardization and consistent performance. It also benefits from the growing adoption of automation-ready workflows, as large diagnostic labs continue to streamline operations.  

Market Ranking

The global nucleic acid isolation and purification market is highly competitive. The key players are expanding their presence through proven chemistries, larger automation footprints, and strong repeat consumables demand. Thermo Fisher Scientific is the market leader. This leading position is supported by its wide range of magnetic bead and column-based kits, strong instrument placements, and a large installed base that drives repeat purchases of reagents and plastics. QIAGEN is well positioned to be the global benchmark player. This is because the spin column workflow is widely used, and the automation options help labs standardize extraction across different sites and with different operators. Roche is another leading player in clinical settings, where a strict regulatory regimen requires consistent performance, workflow integration, and the high turnaround reliability of routine PCR/NAAT testing.

Related Reports:

Nucleic Acid Isolation and Purification Market by Product (Kits, Reagents, Instruments), Method (Column, Magnetic Beads), Type (Genomic DNA, Plasmid DNA, mRNA), Application (Diagnostics, Personalized Medicine), End User (CROs) - Global Forecast to 2030

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