Nucleic Acid Isolation and Purification Market

The global nucleic acid isolation and purification market in terms of revenue was estimated to be worth $6.4 billion in 2023 and is poised to reach $9.4 billion by 2028, growing at a CAGR of 8.1% from 2023 to 2028. The new research study consists of an industry trend analysis of the market. The new research study consists of industry trends, pricing analysis, patent analysis, conference and webinar materials, key stakeholders, and buying behaviour in the market. Factors responsible for the growth of this market include growing research and development activities, advancements in technologies, and growing automation.

Attractive Opportunities in the Nucleic Acid Isolation and Purification Market

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Global NAIP Market Dynamics

DRIVER: Growing demand for molecular diagnostics

Nucleic acid isolation and purification is a critical step in many molecular diagnostic tests, such as those used to detect infectious diseases, genetic disorders, and cancer. The increasing demand for molecular diagnostics is driven by several factors, including the rising prevalence of chronic diseases, the growing awareness of the importance of personalized medicine, the development of new molecular diagnostic tests, and the increasing availability of molecular diagnostic testing. Some specific examples of how molecular diagnostics is used to improve healthcare include cancer diagnosis and treatment, infectious disease diagnosis and treatment, and genetic testing. Overall, the increasing demand for molecular diagnostics is a positive trend for healthcare. Molecular diagnostics helps to improve the diagnosis and treatment of a wide range of diseases and conditions, which leads to better patient outcomes. As the demand for molecular diagnostics continues to grow, so will the demand for nucleic acid isolation and purification products.

RESTRAINT: High cost of automated instruments

The cost of automated instruments for NAIP instruments are associated with additional expenses for reagents, disposables, and maintenance and training. Institutes and companies with smaller R&D budgets cannot afford these expensive instruments. Academic research laboratories in emerging economies also find it difficult to invest in such systems, as they have controlled budgets. Hence, the penetration of these high-cost automated systems is likely to be lower in emerging economies, which impedes the growth of this market.

OPPORTUNITY: Growth opportunities in emerging economies

Emerging economies such as India, Brazil, Turkey, Russia, and South Africa are expected to offer potential growth opportunities for major players operating in this market. This can be attributed to the high disease prevalence, large patient population, improved healthcare infrastructure, increasing disposable income, and growing medical tourism. The North American and European markets for nucleic acid isolation and purification are expected to witness slower growth compared to the market in Asia. Asian countries, specifically China, Japan, and India, provide potential growth opportunities for the nucleic acid isolation and purification kits, reagents, and instruments market. These growth opportunities can mainly be attributed to the growing biopharmaceutical and biotechnology sectors and the development of bio clusters in these countries. This is further supported by the developing healthcare infrastructure and increasing healthcare expenditure. Also, with the large population and increasing need for affordable care, these markets offer significant growth opportunities for players. Advantages such as low manufacturing costs and customs duties attract major pharma and biotech companies to this region.

CHALLENGE: Introduction to alternate technologies

The rise of new technologies, such as microfluidics and digital PCR, is a major challenge for the nucleic acid isolation and purification market. These technologies can offer faster, more efficient, and more accurate ways to isolate and purify nucleic acids. Microfluidics is a technology that manipulates fluids at the microscale. Microfluidic devices can be used to create precise and reproducible fluid flows, which can be used to automate and accelerate the nucleic acid isolation and purification process. Digital PCR is a technology that uses microfluidics to partition a sample into millions of individual droplets. Each droplet contains a single copy of the target nucleic acid. This allows for more sensitive and accurate detection of nucleic acids than traditional PCR methods. In addition to the technologies mentioned above, there are several other new technologies that are emerging that could potentially disrupt the market. For example, researchers are developing new methods for isolating and purifying nucleic acids using nanoparticles and other nanomaterials. Additionally, researchers are developing new methods for isolating and purifying nucleic acids without the need for centrifugation.

Ecosystem of Nucleic Acid Isolation and Purification Market

The Kit Product type segment accounted for the largest share of global nucleic acid isolation and purification industry in 2022.

Based on products, the nucleic acid isolation and purification market has been segmented into kits, reagents, and instruments. The instruments segment is further segmented into automatic and manual instruments. In 2022, the kits segment accounted for the largest share of the global market. Factors responsible for the growth in this market include easy usage and the continuous focus of key market players on developing and launching advanced kits.

Plasmid DNA isolation and purification type segment of the nucleic acid isolation and purification industry expected to grow at a higher growth rate during the forecast period

Based on type, the global nucleic acid isolation and purification market is segmented into messenger RNA isolation and purification, circulating nucleic acid isolation and purification, plasmid DNA isolation and purification, genomic DNA isolation and purification, total RNA isolation and purification, microRNA isolation and purification, and other nucleic acid isolation and purification types. In 2022, the plasmid DNA isolation and purification segment accounted for the major share of the market and the segment is expected to grow at a higher rate during the forecast period due to wide usage of purified plasmid DNA in a variety of various downstream applications, and the increasing application in gene expression profiling.

Personalized medicine application segment of the nucleic acid isolation and purification industry expected to grow at a higher CAGR during the forecast period

Based on application, the global nucleic acid isolation and purification market is segmented into diagnostics, drug discovery & development, personalized medicine, agriculture & animal research, and other applications. In 2022, the diagnostics segment accounted ofr the largest share of the global market. However, the personalized medicine segment is anticipated to experience a higher growth rate in the forecast period due to the escalating demand for genomic data in diagnostic and treatment decision-making, along with ongoing advancements in genomic research. . These products play a crucial role in obtaining high-quality genetic material for personalized medical tests and therapies, driving their market growth.

The Asia Pacific is the fastest growing region for nucleic acid isolation and purification industry.

The nucleic acid isolation and purification market is broadly divided into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa. During the forecast period, Asia Pacific is expected to grow the highest.

The Asia Pacific is the fastest growing and most dynamic market in the world and is estimated to be the most attractive regional market for NAIP. Countries such as China, India, and Japan are expected to witness high growth in the market for NAIP because of the large population in these countries. Also, due to rising health concerns, higher incomes, and better government initiatives, the pharmaceutical market in this region is projected to grow. Together, these factors fuel the growth of the NAIP market in the Asia Pacific region. The growing Asian scientific base and capability, growth in the Asian pharmaceutical market and pharmaceutical manufacturing capabilities, and the large patient pool in several Asia Pacific countries are driving the growth of this regional market. With its huge potential for growth and the low cost of manufacturing, several global pharmaceutical companies are establishing facilities or enhancing their existing facilities in the Asia Pacific.

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Key players in the nucleic acid isolation and purification market are Thermo Fisher Scientific Inc. (US), QIAGEN (Germany), Merck KGaA (Germany), F. Hoffmann-La Roche Ltd. (Switzerland), Promega Corporation (US), Agilent Technologies, Inc. (US), Danaher (US), Bio-Rad Laboratories, Inc. (US), Illumina, Inc. (US), Takara Bio Inc. (Japan), New England Biolabs (US), Abcam Plc (UK), KILPEST India Limited (India), Apical Scientific Sdn. Bhd. (Malaysia), Endress+Hauser Group Services AG (Switzerland), GENAXXON Bioscience GmbH (Germany), LGC Biosearch Technologies (US), Zymo Research Corporation (US), Norgen Biotek Corp. (Canada), Omega Bio-Tek, Inc. (US), FAVORGEN Biotech Corp. (China), TIANGEN Biotech (Beijing) Co., Ltd. (China), AutoGen Inc. (US), PCR Biosystems (UK), and Biogenuix (India).

Scope of the Nucleic Acid Isolation and Purification Industry

This report categorizes the nucleic acid isolation and purification market to forecast revenue and analyze trends in each of the following submarkets:

By Product

• Kits
• Reagents
• Instruments
  • Manual
  • Automatic

By Type

• Plasmid DNA Isolation and Purification
• Total RNA Isolation and Purification
• Circulating Nucleic Acid Isolation and Purification
• Genomic DNA Isolation and Purification
• Messenger RNA Isolation and Purification
• microRNA Isolation and Purification
• Other Nucleic Acid Isolation and Purification Types

By Method

• Column-based Isolation and Purification
• Magnetic Bead-based Isolation and Purification
• Reagent-based Isolation and Purification
• Other Isolation and Purification Methods

By Application

• Diagnostics
• Drug Discovery & Development
• Personalized Medicine
• Agriculture & Animal Research
• Other Applications

By End User

• Hospitals & Diagnostic Centers
• Academic & Government Research Institutes
• Pharmaceutical & Biotechnology Companies
• Contract Research Organizations
• Other End Users

By Region

• North America
  • US
  • Canada
• Europe
  • Germany
  • UK
  • France
  • Italy
  • Spain
  • Rest of Europe (RoE)
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Rest of Asia Pacific (RoAPAC)
• Latin America
  • Brazil
  • Mexico
  • Rest of Latin America (RoLATAM)
• Middle East & Africa
  • Middle East
  • Africa

Recent Developments of Nucleic Acid Isolation and Purification Industry

• In August 2023, Danaher Corporation entered into a definitive agreement to acquire all the outstanding shares of Abcam. Through this development, Abcam is expected to operate as a standalone operating company within Danaher’s Life Sciences segment.
• In July 2023, INOVIQ and Promega announced a global joint marketing agreement for EXO-NET exosome isolation and nucleic acid purification solutions.
• In May 2022, Thermo Fisher partnered with the Qatar Genome Program (QGP), a member of the Qatar Foundation (QF), to accelerate genomic research and clinical applications of predictive genomics in Qatar.

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