Gene Therapy Market

Gene Therapy Market by Vectors (Non-viral(Oligonucleotides), Viral(Retroviral, Adeno-associated)), Indication (Cancer, Neurological, Hepatological Diseases, Duchenne Muscular Dystrophy), Delivery Method (In Vivo, Ex Vivo), Region - Global Forecast to 2027

Report Code: BT 7506 Jul, 2022, by marketsandmarkets.com

[159 Pages Report] The global gene therapy market is projected to reach USD 17.2 billion by 2027 from USD 7.3 billion in 2022, at a CAGR of 18.6% during the forecast period. Factors such as growing approvals of gene therapy products, rising investment in research and development of gene therapies, and are driving the market growth. However, high cost of gene therapy is restraining the growth of this market.

Attractive Opportunities in the Gene Therapy Market

Gene Therapy Market

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Global gene therapy Market Dynamics

DRIVER: Funding for gene therapy research

Gene therapy is one of the latest treatment methods in the healthcare industry. It has shown promising results in treating cancer and other genetic diseases. As a result, the focus on gene therapy research has increased over the last few years. In addition, many companies focus on growth opportunities in this market by launching new and advanced products. For example:

  • In March 2022, the National Heart Lung and Blood Institute granted USD 12 million to an Indiana University School of Medicine researcher. The grant is for exploring major themes in a gene therapy approach to safer and potentially curative treatments for hemophilia.
  • In May 2019, Locana, Inc., a leading RNA-targeting gene therapy company, received USD 55 million in Series A financing led by ARCH Venture Partners, with participation from Temasek and Lightstone Ventures (all existing investors). The company will utilize this fund for its RNA-targeting gene therapy pipeline programs.

OPPORTUNITY: Strong product pipeline

Gene therapy is a promising revenue-generation area for pharmaceutical & biotechnology companies. Currently, most key players are focusing on new gene therapy products to capitalize on the growth opportunities in this market. Some of these products are in the pre-clinical stage, while others are in the clinical phase and expected to secure approval in the coming years. In addition, companies operating in the gene therapy market are focusing on various disease areas, including hemophilia A & B, Fabry disease, wet age-related macular degeneration, mucopolysaccharidosis Type II, ornithine transcarbamylase (OTC) deficiency, achromatopsia, and multiple myeloma. As a result, the patient pool for gene therapies is expected to increase in the coming years.

CHALLENGE: High treatment cost

Currently, the cost of gene therapies is very high, and it can reach up to USD 1 million for one patient depending on the disease condition. Most gene therapy products in the US and EU are covered under reimbursement programs. However, it is difficult for people not covered under insurance to afford such high-cost treatments.

The non-viral vectors segment dominated the gene therapy market in 2021:

On the basis of vectors, the gene therapy market is segmented into non-viral vectors and viral vectors. Non-viral vectors accounted for the larger market share in 2021. Factors such as less immunogenicity of non-viral vectors in comparison to viral vectors coupled with easier mass production of non-viral vectors are driving the growth of this segment.

Gene Therapy Market by Region

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North America was the largest regional market for gene therapy market in 2021.

North America accounted for the largest share of the global gene therapy market in 2021. The significant government and private investments to develop advanced gene therapy products, the high growing adoption rate of these products, and the presence of key market players in the region attribute to a large share of North America in the gene therapy market.

Key Market Players

Key players in the global gene therapy market include Biogen (US), Sarepta Therapeutics (US), Gilead Sciences, Inc. (US), Amgen, Inc. (US), Novartis AG (Switzerland), Orchard Therapeutics Plc (UK), Spark Therapeutics, Inc. (A Part Of ύF. Hoffmann-La Roche) (US), AGC Biologics (US), Anges, Inc. (Japan), Bluebird Bio, Inc. (US), Jazz Pharmaceuticals Plc (Ireland), Dynavax Technologies (US), Human Stem Cells Institute (Russia), Sibiono Genetech Co., Ltd. (China), Shanghai Sunway Biotech Co., Ltd. (China), Uniqure N.V. (Netherland), Gensight Biologics S.A. (France), Celgene Corporation (A Bristol-Myers Squibb Company) (US), Cellectis (France), Sangamo Therapeutics (US), Mustang Bio (US), AGTC (Applied Genetic Technologies Corporation) (US), and Poseida Therapeutics, Inc. (US).

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Scope of the Report

Report Metric

Details

Market size available for years

2021–2027

Base year considered

2021

Forecast period

2022–2027

Forecast units

Value (USD)

Segments covered

Vectors, Indication, Delivery Method, and Region

Geographies covered

North America, Europe, Asia Pacific, and Rest of the World

Companies covered

Biogen (US), Sarepta Therapeutics (US), Gilead Sciences, Inc. (US), Amgen, Inc. (US), Novartis Ag (Switzerland), Orchard Therapeutics Plc (UK), Spark Therapeutics, Inc. (A Part Of ύF. Hoffmann-La Roche) (US), Agc Biologics (US), Anges, Inc. (Japan), Bluebird Bio, Inc. (US), Jazz Pharmaceuticals Plc (Ireland), Dynavax Technologies (US), Human Stem Cells Institute (Russia), Sibiono Genetech Co., Ltd. (China), Shanghai Sunway Biotech Co., Ltd. (China), Uniqure N.V. (Netherland), Gensight Biologics S.A. (France), Celgene Corporation (A Bristol-Myers Squibb Company) (US), Cellectis (France), Sangamo Therapeutics (US), Mustang Bio (US), AGTC (Applied Genetic Technologies Corporation) (US), Poseida Therapeutics, Inc. (US)

This report categorizes the gene therapy market into the following segments and subsegments:

Gene Therapy Market, by Vectors

  • Non-viral Vectors
    • Oligonucleotides
    • Other Non-viral Vectors
  • Viral Vectors
    • Retro Viral Vectors
    • Adeno-associated Virus Vectors
    • Other Viral Vectors

Gene Therapy Market, by Indication

  • Neurological Diseases
  • Cancer
  • DMD (Duchenne Muscular Dystrophy)
  • Hepatological Diseases
  • Other Indications

Gene Therapy Market, by Delivery Method

gene therapy Market, by Region

  • North America
    • US
    • Canada
  • Europe
    • Germany
    • UK
    • France
    • Italy
    • Spain
    • Rest of Europe (RoE)
  • Asia Pacific (APAC)
    • China
    • Japan
    • Rest of Asia Pacific (RoAPAC)
  • Rest of the World (RoW)

Recent Developments

  • In February 2022, Sarepta Therpeutics (US) announced a collaboration to use GenEdit’s NanoGalaxy platform and Sarepta’s gene editing technology to develop gene editing therapeutics to treat neuromuscular diseases.
  • In May 2022, Novartis AG (Switzerland) received FDA approval for KYMRIAH for adult patients with relapsed or refractory follicular lymphoma after two or more lines of systemic therapy.

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TABLE OF CONTENTS

1 INTRODUCTION (Page No. - 23)
    1.1 STUDY OBJECTIVES
    1.2 MARKET DEFINITION
           1.2.1 INCLUSIONS AND EXCLUSIONS
    1.3 STUDY SCOPE
           1.3.1 MARKETS COVERED
    1.4 YEARS CONSIDERED
    1.5 CURRENCY CONSIDERED
    1.6 LIMITATIONS
    1.7 STAKEHOLDERS
    1.8 SUMMARY OF CHANGES

2 RESEARCH METHODOLOGY (Page No. - 26)
    2.1 RESEARCH DATA
          FIGURE 1 RESEARCH DESIGN
           2.1.1 SECONDARY DATA
                    FIGURE 2 KEY DATA FROM SECONDARY SOURCES
           2.1.2 PRIMARY DATA
                    FIGURE 3 BREAKDOWN OF PRIMARY INTERVIEWS: BY COMPANY TYPE, DESIGNATION, AND REGION
    2.2 MARKET SIZE ESTIMATION
           2.2.1 BOTTOM-UP APPROACH
           2.2.2 COMPANY REVENUE ANALYSIS
                    FIGURE 4 COMPANY REVENUE ANALYSIS
           2.2.3 GROWTH FORECAST
    2.3 MARKET BREAKDOWN AND DATA TRIANGULATION
          FIGURE 5 DATA TRIANGULATION METHODOLOGY
    2.4 RESEARCH ASSUMPTIONS
    2.5 RISK ASSESSMENT

3 EXECUTIVE SUMMARY (Page No. - 32)
    FIGURE 6 GENE THERAPY MARKET, BY VECTOR, 2022 VS. 2027 (USD MILLION)
    FIGURE 7 GENE THERAPY MARKET, BY DELIVERY METHOD, 2022 VS. 2027 (USD MILLION)
    FIGURE 8 GENE THERAPY MARKET, BY INDICATION, 2022 VS. 2027 (USD MILLION)
    FIGURE 9 GENE THERAPY MARKET: REGIONAL SNAPSHOT

4 PREMIUM INSIGHTS (Page No. - 35)
    4.1 GENE THERAPY MARKET OVERVIEW
          FIGURE 10 HIGH INCIDENCE OF CANCER & OTHER TARGETED DISEASES TO DRIVE MARKET GROWTH
    4.2 NORTH AMERICA: GENE THERAPY MARKET, BY VECTOR (2021)
          FIGURE 11 NON-VIRAL VECTORS DOMINATE NORTH AMERICAN GENE THERAPY MARKET
    4.3 GEOGRAPHICAL SNAPSHOT OF THE GENE THERAPY MARKET
          FIGURE 12 APAC COUNTRIES TO REGISTER HIGHEST GROWTH DURING FORECAST PERIOD

5 MARKET OVERVIEW (Page No. - 37)
    5.1 INTRODUCTION
    5.2 MARKET DYNAMICS
          FIGURE 13 GENE THERAPY MARKET: DRIVERS, OPPORTUNITIES, AND CHALLENGES
           5.2.1 DRIVERS
                    5.2.1.1 High incidence of cancer and other target diseases
                                TABLE 1 NUMBER OF NEW CANCER CASES, 2020 VS. 2025
                    5.2.1.2 Product approvals
                                TABLE 2 PRODUCT APPROVALS, 2015–2021
                    5.2.1.3 Funding for gene therapy research
           5.2.2 OPPORTUNITIES
                    5.2.2.1 Strong product pipeline
                                TABLE 3 GENE THERAPY MARKET: INDICATIVE LIST OF PIPELINE DRUGS
           5.2.3 CHALLENGES
                    5.2.3.1 High treatment costs
                                TABLE 4 PRICE OF GENE THERAPY PRODUCTS, 2021
    5.3 PRICING ANALYSIS
    5.4 TECHNOLOGY ANALYSIS
          FIGURE 14 KEY STEPS IN GENE THERAPY
    5.5 SUPPLY CHAIN ANALYSIS
           5.5.1 PROMINENT COMPANIES
           5.5.2 SMALL AND MEDIUM-SIZED ENTERPRISES (SMES)
           5.5.3 END USERS
                    FIGURE 15 GENE THERAPY MARKET: SUPPLY CHAIN ANALYSIS
    5.6 ECOSYSTEM ANALYSIS OF GENE THERAPY MARKET
          TABLE 5 STAKEHOLDERS IN THE GENE THERAPY ECOSYSTEM AND THEIR ROLES
    5.7 KEY CONFERENCES AND EVENTS IN 2022–2023
          TABLE 6 GENE THERAPY MARKET: DETAILED LIST OF CONFERENCES AND EVENTS
    5.8 REGULATORY ANALYSIS
          TABLE 7 NORTH AMERICA: LIST OF REGULATORY BODIES, GOVERNMENT AGENCIES, AND OTHER ORGANIZATIONS
          TABLE 8 EUROPE: LIST OF REGULATORY BODIES, GOVERNMENT AGENCIES, AND OTHER ORGANIZATIONS
          TABLE 9 ASIA PACIFIC: LIST OF REGULATORY BODIES, GOVERNMENT AGENCIES, AND OTHER ORGANIZATIONS
          TABLE 10 REST OF THE WORLD: LIST OF REGULATORY BODIES, GOVERNMENT AGENCIES, AND OTHER ORGANIZATIONS
    5.9 PORTER’S FIVE FORCES ANALYSIS
          TABLE 11 GENE THERAPY MARKET: PORTER’S FIVE FORCES ANALYSIS
           5.9.1 THREAT OF NEW ENTRANTS
           5.9.2 THREAT OF SUBSTITUTES
           5.9.3 BARGAINING POWER OF SUPPLIERS
           5.9.4 BARGAINING POWER OF BUYERS
           5.9.5 COMPETITIVE RIVALRY AMONG EXISTING PLAYERS
    5.10 KEY STAKEHOLDERS AND BUYING CRITERIA
           5.10.1 KEY STAKEHOLDERS IN BUYING PROCESS
                     FIGURE 16 INFLUENCE OF STAKEHOLDERS IN BUYING PROCESS OF GENE THERAPY PRODUCTS
           5.10.2 BUYING CRITERIA FOR GENE THERAPY PRODUCTS
                     FIGURE 17 KEY BUYING CRITERIA FOR END USERS

6 GENE THERAPY MARKET, BY VECTOR (Page No. - 49)
    6.1 INTRODUCTION
          TABLE 12 GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
    6.2 NON-VIRAL VECTORS
          TABLE 13 GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)
          TABLE 14 GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
           6.2.1 OLIGONUCLEOTIDES
                    6.2.1.1 Oligonucleotides account for the largest share of the non-viral vectors market
                                TABLE 15 GENE THERAPY MARKET FOR OLIGONUCLEOTIDES, BY REGION, 2020–2027 (USD MILLION)
           6.2.2 OTHER NON-VIRAL VECTORS
                    TABLE 16 GENE THERAPY MARKET FOR OTHER NON-VIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)
    6.3 VIRAL VECTORS
          TABLE 17 GENE THERAPY MARKET FOR VIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)
          TABLE 18 GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
           6.3.1 RETROVIRAL VECTORS
                    TABLE 19 GENE THERAPY MARKET FOR RETROVIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)
                    TABLE 20 GENE THERAPY MARKET FOR RETROVIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                    6.3.1.1 Gamma-retroviral vectors
                               6.3.1.1.1 Availability of wide range of gamma-retroviral vectors supports market growth
                                              TABLE 21 GENE THERAPY MARKET FOR GAMMA-RETROVIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)
                    6.3.1.2 Lentiviral vectors
                               6.3.1.2.1 North America to dominate lentiviral vectors market
                                              TABLE 22 GENE THERAPY MARKET FOR LENTIVIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)
           6.3.2 ADENO-ASSOCIATED VIRUS VECTORS
                    6.3.2.1 Potential applications in in vivo applications to drive interest in AAV vectors
                                TABLE 23 GENE THERAPY MARKET FOR AAV VECTORS, BY REGION, 2020–2027 (USD MILLION)
           6.3.3 OTHER VIRAL VECTORS
                    TABLE 24 GENE THERAPY MARKET FOR OTHER VIRAL VECTORS, BY REGION, 2020–2027 (USD MILLION)

7 GENE THERAPY MARKET, BY INDICATION (Page No. - 56)
    7.1 INTRODUCTION
          TABLE 25 GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
    7.2 NEUROLOGICAL DISEASES
           7.2.1 NEUROLOGICAL DISEASES TO FORM THE LARGEST INDICATION SEGMENT IN THIS MARKET
                    TABLE 26 GENE THERAPY MARKET FOR NEUROLOGICAL DISEASES, BY REGION, 2020–2027 (USD MILLION)
    7.3 CANCER
           7.3.1 GROWING DEMAND FOR CANCER THERAPIES TO DRIVE MARKET GROWTH
                    TABLE 27 NUMBER OF NEW CANCER CASES, BY TYPE, 2020–2040
                    TABLE 28 GENE THERAPY MARKET FOR CANCER, BY REGION, 2020–2027 (USD MILLION)
    7.4 DUCHENNE MUSCULAR DYSTROPHY
           7.4.1 RISING PREVALENCE OF DMD TO SUPPORT MARKET GROWTH
                    TABLE 29 GENE THERAPY MARKET FOR DMD, BY REGION, 2020–2027 (USD MILLION)
    7.5 HEPATOLOGICAL DISEASES
           7.5.1 INCREASING PREVALENCE OF HEPATITIS B INFECTIONS TO SUPPORT MARKET GROWTH
                    TABLE 30 GENE THERAPY MARKET FOR HEPATOLOGICAL DISEASES, BY REGION, 2020–2027 (USD MILLION)
    7.6 OTHER INDICATIONS
          TABLE 31 GENE THERAPY MARKET FOR OTHER INDICATIONS, BY REGION, 2020–2027 (USD MILLION)

8 GENE THERAPY MARKET, BY DELIVERY METHOD (Page No. - 62)
    8.1 INTRODUCTION
          TABLE 32 GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
    8.2 IN VIVO GENE THERAPY
           8.2.1 IN VIVO GENE THERAPY TO DOMINATE MARKET
                    TABLE 33 IN VIVO GENE THERAPY MARKET, BY REGION, 2020–2027 (USD MILLION)
    8.3 EX VIVO GENE THERAPY
           8.3.1 EX VIVO GENE THERAPY SEGMENT TO WITNESS HIGH GROWTH
                    TABLE 34 EX VIVO GENE THERAPY MARKET, BY REGION, 2020–2027 (USD MILLION)

9 GENE THERAPY MARKET, BY REGION (Page No. - 65)
    9.1 INTRODUCTION
          TABLE 35 GENE THERAPY MARKET, BY REGION, 2020–2027 (USD MILLION)
    9.2 NORTH AMERICA
          FIGURE 18 NORTH AMERICA: GENE THERAPY MARKET SNAPSHOT
          TABLE 36 NORTH AMERICA: GENE THERAPY MARKET, BY COUNTRY, 2020–2027 (USD MILLION)
          TABLE 37 NORTH AMERICA: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
          TABLE 38 NORTH AMERICA: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 39 NORTH AMERICA: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 40 NORTH AMERICA: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 41 NORTH AMERICA: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
          TABLE 42 NORTH AMERICA: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.2.1 US
                    9.2.1.1 US dominates the global gene therapy market
                                TABLE 43 LIST OF GENE THERAPY PIPELINE CANDIDATES OF US-BASED COMPANIES
                                TABLE 44 US FDA GENE THERAPY PRODUCT APPROVALS
                                TABLE 45 US: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 46 US: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 47 US: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 48 US: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 49 US: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 50 US: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.2.2 CANADA
                    9.2.2.1 Growing burden of cancer supports market growth in Canada
                                TABLE 51 CANADA: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 52 CANADA: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 53 CANADA: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 54 CANADA: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 55 CANADA: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 56 CANADA: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
    9.3 EUROPE
           TABLE 57 EUROPE: GENE THERAPY MARKET, BY COUNTRY, 2020–2027 (USD MILLION)
           TABLE 58 EUROPE: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
           TABLE 59 EUROPE: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
           TABLE 60 EUROPE: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
           TABLE 61 EUROPE: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
           TABLE 62 EUROPE: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
           TABLE 63 EUROPE: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.3.1 GERMANY
                    9.3.1.1 Germany dominates European gene therapy market
                                TABLE 64 GERMANY: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 65 GERMANY: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 66 GERMANY: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 67 GERMANY: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 68 GERMANY: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 69 GERMANY: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 70 GERMANY: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.3.2 FRANCE
                    9.3.2.1 Increasing cancer incidence to support market growth
                                TABLE 71 FRANCE: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 72 FRANCE: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 73 FRANCE: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 74 FRANCE: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 75 FRANCE: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 76 FRANCE: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 77 FRANCE: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.3.3 UK
                    9.3.3.1 Rising incidence of melanoma to support market growth in UK
                                TABLE 78 UK: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 79 UK: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 80 UK: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 81 UK: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 82 UK: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 83 UK: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 84 UK: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.3.4 ITALY
                    9.3.4.1 High incidence of targeted diseases and increasing healthcare spending to drive Italian market growth
                                TABLE 85 ITALY: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 86 ITALY: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 87 ITALY: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 88 ITALY: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 89 ITALY: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 90 ITALY: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 91 ITALY: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.3.5 SPAIN
                    9.3.5.1 Rising cancer incidence and increasing healthcare expenditure to support market growth in Spain
                                TABLE 92 SPAIN: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 93 SPAIN: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 94 SPAIN: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 95 SPAIN: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 96 SPAIN: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 97 SPAIN: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 98 SPAIN: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.3.6 REST OF EUROPE
                    TABLE 99 ROE: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                    TABLE 100 ROE: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                    TABLE 101 ROE: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                    TABLE 102 ROE: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                    TABLE 103 ROE: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                    TABLE 104 ROE: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
    9.4 ASIA PACIFIC
          FIGURE 19 ASIA PACIFIC: GENE THERAPY MARKET SNAPSHOT
                              TABLE 105 ASIA PACIFIC: GENE THERAPY MARKET, BY COUNTRY, 2020–2027 (USD MILLION)
          TABLE 106 ASIA PACIFIC: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
          TABLE 107 ASIA PACIFIC: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 108 ASIA PACIFIC: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 109 ASIA PACIFIC: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 110 ASIA PACIFIC: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
          TABLE 111 ASIA PACIFIC: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.4.1 JAPAN
                    9.4.1.1 Japan dominates the APAC gene therapy market
                                TABLE 112 JAPAN: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 113 JAPAN: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 114 JAPAN: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 115 JAPAN: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 116 JAPAN: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 117 JAPAN: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 118 JAPAN: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.4.2 CHINA
                    9.4.2.1 Rising prevalence of cancer and established base for gene therapy to support market growth in China
                                TABLE 119 CHINA: CANCER INCIDENCE, BY TYPE, 2020 VS. 2040
                                TABLE 120 CHINA: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                                TABLE 121 CHINA: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 122 CHINA: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 123 CHINA: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                                TABLE 124 CHINA: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                                TABLE 125 CHINA: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
           9.4.3 REST OF ASIA PACIFIC
                    TABLE 126 ROAPAC: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
                    TABLE 127 ROAPAC: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                    TABLE 128 ROAPAC: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
                    TABLE 129 ROAPAC: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
                    TABLE 130 ROAPAC: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
                    TABLE 131 ROAPAC: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)
    9.5 REST OF THE WORLD
          TABLE 132 ROW: GENE THERAPY MARKET, BY VECTOR, 2020–2027 (USD MILLION)
          TABLE 133 ROW: GENE THERAPY MARKET FOR NON-VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 134 ROW: GENE THERAPY MARKET, BY DELIVERY METHOD, 2020–2027 (USD MILLION)
          TABLE 135 ROW: GENE THERAPY MARKET FOR VIRAL VECTORS, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 136 ROW: RETROVIRAL VECTORS MARKET, BY TYPE, 2020–2027 (USD MILLION)
          TABLE 137 ROW: GENE THERAPY MARKET, BY INDICATION, 2020–2027 (USD MILLION)

10 COMPETITIVE LANDSCAPE (Page No. - 102)
     10.1 OVERVIEW
             FIGURE 20 KEY DEVELOPMENTS IN THE GENE THERAPY MARKET
     10.2 MARKET SHARE ANALYSIS, 2021
             FIGURE 21 GENE THERAPY MARKET SHARE ANALYSIS, 2021
             TABLE 138 GENE THERAPY MARKET: DEGREE OF COMPETITION
     10.3 REVENUE SHARE ANALYSIS OF TOP MARKET PLAYERS
             FIGURE 22 REVENUE SHARE ANALYSIS OF TOP PLAYERS IN GENE THERAPY, 2019–2021
     10.4 COMPANY EVALUATION QUADRANT
             10.4.1 STARS
             10.4.2 EMERGING LEADERS
             10.4.3 PERVASIVE PLAYERS
             10.4.4 PARTICIPANTS
                        FIGURE 23 GENE THERAPY MARKET: COMPANY EVALUATION QUADRANT, 2021
     10.5 COMPANY FOOTPRINT ANALYSIS
             10.5.1 PRODUCT FOOTPRINT OF COMPANIES
                        TABLE 139 GENE THERAPY MARKET: COMPANY PRODUCT FOOTPRINT (2021) ACROSS INDICATIONS
     10.6 COMPETITIVE SCENARIO
              TABLE 140 PRODUCT APPROVALS, 2018–2022
              TABLE 141 DEALS, 2018–2022
              TABLE 142 OTHER DEVELOPMENTS, 2018-2022

11 COMPANY PROFILES (Page No. - 110)
(Business Overview, Products/Services/Solutions Offered, MnM View, Key Strengths and Right to Win, Strategic Choices Made, Weaknesses and Competitive Threats, Recent Developments)*
     11.1 BIOGEN
              TABLE 143 BIOGEN: BUSINESS OVERVIEW
              FIGURE 24 BIOGEN: COMPANY SNAPSHOT
     11.2 SAREPTA THERAPEUTICS
              TABLE 144 SAREPTA THERAPEUTICS: BUSINESS OVERVIEW
              FIGURE 25 SAREPTA THERAPEUTICS: COMPANY SNAPSHOT
     11.3 GILEAD SCIENCES, INC.
              TABLE 145 GILEAD SCIENCES INC: BUSINESS OVERVIEW
              FIGURE 26 GILEAD SCIENCES, INC.: COMPANY SNAPSHOT
     11.4 AMGEN, INC.
              TABLE 146 AMGEN INC: BUSINESS OVERVIEW
              FIGURE 27 AMGEN, INC.: COMPANY SNAPSHOT
     11.5 NOVARTIS AG
              TABLE 147 NOVARTIS AG: BUSINESS OVERVIEW
              FIGURE 28 NOVARTIS AG: COMPANY SNAPSHOT
     11.6 ORCHARD THERAPEUTICS PLC
              TABLE 148 ORCHARD THERAPEUTICS PLC: BUSINESS OVERVIEW
              FIGURE 29 ORCHARD THERAPEUTICS PLC: COMPANY SNAPSHOT
     11.7 SPARK THERAPEUTICS, INC. (AN F. HOFFMANN-LA ROCHE COMPANY)
              TABLE 149 SPARK THERAPEUTICS INC: BUSINESS OVERVIEW
     11.8 AGC BIOLOGICS
              TABLE 150 AGC BIOLOGICS: BUSINESS OVERVIEW
     11.9 ANGES, INC.
              TABLE 151 ANGES INC: BUSINESS OVERVIEW
              FIGURE 30 ANGES, INC.: COMPANY SNAPSHOT
     11.1 BLUEBIRD BIO, INC.
              TABLE 152 BLUEBIRD BIO: BUSINESS OVERVIEW
              FIGURE 31 BLUEBIRD BIO: COMPANY SNAPSHOT
     11.11 JAZZ PHARMACEUTICALS PLC
              TABLE 153 JAZZ PHARMACEUTICALS: BUSINESS OVERVIEW
              FIGURE 32 JAZZ PHARMACEUTICALS PLC: COMPANY SNAPSHOT
     11.12 DYNAVAX TECHNOLOGIES
              TABLE 154 DYNAVAX TECHNOLOGIES: BUSINESS OVERVIEW
              FIGURE 33 DYNAVAX TECHNOLOGIES: COMPANY SNAPSHOT
     11.13 HUMAN STEM CELLS INSTITUTE
              TABLE 155 HUMAN STEM CELLS INSTITUTE: BUSINESS OVERVIEW
     11.14 SIBIONO GENETECH CO., LTD.
              TABLE 156 SIBIONO GENETECH CO LTD: BUSINESS OVERVIEW
     11.15 SHANGHAI SUNWAY BIOTECH CO., LTD.
              TABLE 157 SHANGHAI SUNWAY BIOTECH CO LTD: BUSINESS OVERVIEW
     11.16 UNIQURE N.V.
              TABLE 158 UNIQURE NV: BUSINESS OVERVIEW
     11.17 GENSIGHT BIOLOGICS S.A.
              TABLE 159 GENSIGHT BIOLOGICS SA: BUSINESS OVERVIEW
     11.18 CELGENE CORPORATION (A BRISTOL-MYERS SQUIBB COMPANY)
              TABLE 160 CELGENE CORPORATION: BUSINESS OVERVIEW
     11.19 CELLECTIS
              TABLE 161 CELLECTIS: BUSINESS OVERVIEW
     11.2 SANGAMO THERAPEUTICS
              TABLE 162 SANGAMO THERAPEUTICS: BUSINESS OVERVIEW
     11.21 MUSTANG BIO
              TABLE 163 MUSTANG BIO: BUSINESS OVERVIEW
     11.22 AGTC (APPLIED GENETIC TECHNOLOGIES CORPORATION)
              TABLE 164 AGTC: BUSINESS OVERVIEW
     11.23 POSEIDA THERAPEUTICS, INC.
              TABLE 165 POSEIDA THERAPEUTICS INC: BUSINESS OVERVIEW

*Business Overview, Products/Services/Solutions Offered, MnM View, Key Strengths and Right to Win, Strategic Choices Made, Weaknesses and Competitive Threats, Recent Developments might not be captured in case of unlisted companies.

12 APPENDIX (Page No. - 153)
     12.1 DISCUSSION GUIDE
     12.2 KNOWLEDGESTORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL
     12.3 AVAILABLE CUSTOMIZATION OPTIONS
     12.4 RELATED REPORTS
     12.5 AUTHOR DETAILS

This research study involved the extensive use of secondary sources, directories, and databases to identify and collect valuable information to analyze the global gene therapy market. In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, to obtain and verify critical qualitative and quantitative information and assess the growth prospects of the market. The global market size estimated through secondary research was then triangulated with inputs from primary research to arrive at the final market size.

Secondary Research

The secondary sources referred to for this research study included corporate filings (such as annual reports, SEC filings, and financial statements), research journals, press releases, and trade, business, and professional associations. These secondary sources were used to identify and collect useful information for this extensive, technical, and commercial study of the gene therapy market. Secondary research was mainly used to obtain key information about the industry’s total pool of key players, market classification and segmentation according to industry trends to the bottom-most level, market trends, and key developments by both public and private organizations in the gene therapy market.

Primary Research

Extensive primary research was conducted after acquiring basic knowledge about the global gene therapy market scenario through secondary research. Several primary interviews were conducted with market experts from the demand side, such as experts from the supply side, such as C-level and D-level executives, product managers, marketing & sales managers of key manufacturers, distributors, and channel partners. These interviews were conducted across four major regions, namely, North America, Europe, the Asia Pacific, and Rest of the World. This primary data was collected through questionnaires, e-mails, online surveys, personal interviews, and telephonic interviews.

The following is a breakdown of the primary respondents:

Gene Therapy Market Size, and Share

To know about the assumptions considered for the study, download the pdf brochure

Market Size Estimation

The global size of the gene therapy market was estimated through multiple approaches. A detailed market estimation approach was followed to estimate and validate the value of the market and other dependent submarkets. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:

  • The key players in the industry and market have been identified through extensive primary and secondary research.
  • The revenues generated from the gene therapy business of leading players have been determined through primary and secondary research.
  • All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources.

Data Triangulation

After arriving at the market size from the market size estimation process explained above, the total market was divided into several segments and subsegments. To complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments, data triangulation and market breakdown procedures were employed, wherever applicable.

Report Objectives

  • To define, describe, and forecast the gene therapy market on the basis of vectors, indication, delivery method, and region
  • To provide detailed information regarding the major factors influencing the market growth, such as drivers, restraints, opportunities, and challenges
  • To strategically analyze the micromarkets with respect to individual growth trends, future prospects, and contributions to the overall gene therapy market
  • To analyze the opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
  • To forecast the revenue of the market segments with respect to four main regions, namely, North America (US and Canada), Europe (Germany, France, UK, Italy, Spain, and the Rest of Europe), Asia Pacific (China, Japan, and the Rest of Asia Pacific), and Rest of the World.
  • To profile the key market players and comprehensively analyze their market shares and core competencies
  • To track and analyze competitive developments such as product launches, agreements, partnerships, acquisitions, business expansions, and research & development activities in the gene therapy market

Available Customizations

With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for this report:

Gene Therapy Market Size,  Share & Growth Report
Report Code
BT 7506
Published ON
Jul, 2022
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