Oligonucleotide Synthesis Market

Oligonucleotide Synthesis Market by Product (Probe, Linkers, Adaptor, Drugs, Reagent, Equipment), Type (Custom, Pre Design), Application (PCR, DNA, RNAi, Research, Therapeutic), End User (Hospital, Pharmaceutical, Biotechnology) - Global Forecast to 2024

Report Code: BT 2680 Apr, 2019, by marketsandmarkets.com

[225 Pages Report] The global oligonucleotide synthesis market is projected to reach USD 8.2 billion by 2024 from USD 4.3 billion in 2019, at a CAGR of 13.7% during the forecast period. This market is experiencing significant growth due to the increasing research activities in the pharma and biotech sectors and the rising demand for innovative diagnostic and therapeutic techniques.

Oligonucleotide Synthesis Market

Oligonucleotide-based drugs segment to dominate the synthesized oligos market during the forecast period

The synthesized oligos market, by product, is segmented into oligonucleotide-based drugs, primers, probes, large-scale synthesized oligos, intermediate-scale synthesized oligos, and linkers and adaptors. Of these, oligonucleotide-based accounted for over 50% of the synthesized oligos market share in 2018. This segment is also estimated to grow at the highest CAGR during the forecast period due to the increasing demand for oligonucleotide-based drugs and the influx of new customers in the oligo drug development arena. Apart from this, there are a few oligonucleotide-based drugs in Phase III and FDA review, and these drugs might be launched over the next five years which will positively impact this market.

Hospitals to account for the largest share of the oligonucleotide synthesis market, by end user, in 2018

Based on end user, the oligonucleotide synthesis market is segmented into academic research institutes, diagnostic laboratories, pharmaceutical & biotechnology companies, and hospitals. Hospitals contributed to the highest revenue generated among these segments within the oligonucleotide synthesis market in 2018. The significant number of inpatient and outpatient visits in hospitals coupled with the high requirement of oligonucleotide drugs to cater to the demand from the vast patient pool suffering from diseases such as Duchenne muscular dystrophy, spinal muscular atrophy, and hepatic veno-occlusive disease, is driving the market growth in the segment.

Oligonucleotide Synthesis Market

North America was the largest regional market for oligonucleotide synthesis in 2018

The oligonucleotide synthesis market is segmented into North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. In 2018, North America was the largest market for share, followed by Europe. Moreover, North America is estimated to register the highest CAGR during the forecast period primarily due to the increasing R&D activities and the growing number of oligonucleotide-based drugs/therapies being approved by the FDA.

Key Market Players

The prominent players operating in this market include Agilent Technologies, Inc. (US), ATDBio Ltd. (UK), Bio-Synthesis, Inc. (US), BioAutomation Corporation (US), LGC Biosearch Technologies (US), Biogen International (US), Sarepta Therapeutics (US), Eurofins Genomics (Germany), Eurogentec (Belgium), GeneDesign, Inc. (Japan), GE Healthcare (US), GenScript, Inc. (US), Integrated DNA Technologies (IDT, US), Nitto Denko Avecia, Inc. (US), Sarepta Therapeutics (US), Thermo Fisher Scientific, Inc. (US), TriLink BioTechnologies (US), and Sigma-Aldrich Corporation (US) (a part of Merck KGAA).

Sigma-Aldrich Corporation (US) was one of the leading players in the oligonucleotide synthesis market in 2018. The company is innovation-centric and focuses on R&D to develop and introduce new enhanced products in the market. It is a leading supplier of custom DNA and RNA oligonucleotides for the life sciences research community in North America. Thermo Fisher Scientific is another leading player in the oligonucleotide synthesis market. The company’s strong brand recognition and extensive product portfolio in this market are its key strengths. To maintain its leading position in the market, the company adopts organic as well as inorganic growth strategies such as expansions and acquisitions.

Recent Developments

  • In Febuary 2019, Thermo Fisher Scientific entered into an agreement with BioNTech (Germany). Under the terms of this agreement, BioNTech's messenger RNA (mRNA) manufacturing platform will be supported by Thermo Fisher through the supply of nucleotides, enzymes, and other critical raw materials
  • In Febuary 2019, IDT expanded its courier zones of free next-day delivery service to scientists based in Cambridge, Oxford, and London. This service expansion will help IDT increase its customer base, and also enable projects to be started and finished sooner.
  • In March 2018, Danaher acquired IDT, whichenhanced Danaher’s Life Sciences platform and expanded its customer base.

Key Questions Addressed by the Report

  • Where will all these developments take the industry in the mid-to-long term?
  • What are the recent trends affecting the oligonucleotide synthesis market?
  • Will oligonucleotide-based drugs be next game changer in the oligonucleotide synthesis market?
  • Who are the key players in the market and how intense is the competition?
  • What are the new application areas of oligonucleotide synthesis?

To speak to our analyst for a discussion on the above findings, click Speak to Analyst

Table of Contents

1 Introduction (Page No. - 21)
    1.1 Objectives of the Study
    1.2 Definition
    1.3 Market Scope
           1.3.1 Markets Covered
           1.3.2 Years Considered for the Study
    1.4 Currency
    1.5 Limitations
    1.6 Stakeholders

2 Research Methodology (Page No. - 24)
    2.1 Research Data
    2.2 Secondary Data
           2.2.1 Secondary Sources
    2.3 Primary Data
           2.3.1 Key Data From Primary Sources
    2.4 Market Size Estimation
           2.4.1 Market Size Estimation: Bottom-Up Approach
           2.4.2 Market Size Estimation: Top-Down Approach
    2.5 Market Breakdown and Data Triangulation
    2.6 Assumptions for the Study

3 Executive Summary (Page No. - 31)

4 Premium Insights (Page No. - 36)
    4.1 Attractive Opportunities in the Oligonucleotide Synthesis Market
    4.2 Synthesized Oligos Market, By Product
    4.3 Synthesized Oligos Market, By Type
    4.4 Asia Pacific: Oligonucleotide Synthesis Market, By Research Application and Country (2019)
    4.5 Oligonucleotide Synthesis Market, By Therapeutic Application
    4.6 Oligonucleotide Synthesis Market, By End User
    4.7 Geographic Snapshot: Oligonucleotide Synthesis Market

5 Market Overview (Page No. - 41)
    5.1 Introduction
    5.2 Market Dynamics
           5.2.1 Market Drivers
                    5.2.1.1 Increasing Use of Synthesized Oligos in Molecular Diagnostics and Clinical Applications
                    5.2.1.2 Increasing Government Investments and R&D Expenditure in Pharmaceutical and Biotechnology Companies
                    5.2.1.3 Rise in Venture Capital Investments
           5.2.2 Market Restraints
                    5.2.2.1 Price Erosion of Synthesized Oligos
                    5.2.2.2 Lack of A Unified Set of Regulations for Therapeutic Oligos
           5.2.3 Market Opportunities
                    5.2.3.1 Emerging Asian Markets
           5.2.4 Market Challenges
                    5.2.4.1 Large-Scale Synthesis of Oligos
                    5.2.4.2 Delivery of Oligonucleotide Drugs to Specific Targets

6 Oligonucleotide Synthesis Market, By Product (Page No. - 48)
    6.1 Introduction
    6.2 Synthesized Oligos
           6.2.1 Synthesized Oligos Market, By Product
                    6.2.1.1 Oligonucleotide-Based Drugs
                               6.2.1.1.1 Oligonucleotide-Based Drugs Dominate the Synthesized Oligos Market, By Product
                    6.2.1.2 Primers
                               6.2.1.2.1 Growing Research Activity Drives the Market for Primers
                    6.2.1.3 Probes
                               6.2.1.3.1 Probes are Designed to Detect Various Infectious Agents
                    6.2.1.4 Intermediate-Scale Synthesized Oligos
                               6.2.1.4.1 The Increasing Demand for Synthesized Oligos and Innovations in Manufacturing Techniques Drives the Market.
                    6.2.1.5 Large-Scale Synthesized Oligos
                               6.2.1.5.1 Increasing Demand for Large Quantities of Modified and Unmodified Oligos to Drive the Market
                    6.2.1.6 Linkers & Adaptors
                               6.2.1.6.1 Linkers are Used to Add Restriction Sites in DNA
           6.2.2 Synthesized Oligos Market, By Type
                    6.2.2.1 Predesigned Oligos
                               6.2.2.1.1 Predesigned Oligos Dominate the Oligonucleotide Synthesis Market, By Type
                    6.2.2.2 Custom Oligos
                               6.2.2.2.1 Increasing Number of Clinical and Pre-Clinical Research to Drive the Market for Custom Oligos
    6.3 Reagents
    6.4 Equipment

7 Oligonucleotide Synthesis Market, By Application (Page No. - 63)
    7.1 Introduction
    7.2 Therapeutic Applications
           7.2.1 DNA & Antisense Oligonucleotide-Based Therapies
                    7.2.1.1 DNA & Antisense Oligos Form the Largest Segment in the Therapeutic Applications Market
           7.2.2 RNAI Oligonucleotide-Based Therapies
                    7.2.2.1 Significant Initiatives By Pharmaceutical and Biotechnology Companies to Drive the Market for RNAI Oligonucleotide-Based Therapies
           7.2.3 CPG Oligonucleotide-Based Therapies
                    7.2.3.1 This Market Segment is in the Initial Stage, and Significant Growth Might Be Observed During the Forecast Period
    7.3 Diagnostic Applications
    7.4 Research Applications
           7.4.1 PCR
                    7.4.1.1 Increasing Use of PCR in Research to Drive Market Growth
           7.4.2 QPCR
                    7.4.2.1 Its Cost-Effectiveness, Concurrent Monitoring of Expression Levels of Multiple Genetic Messages in Real Time, and High Sensitivity Make QPCR A Vital Tool for Quantification of Nucleic Acids
           7.4.3 Sequencing
                    7.4.3.1 Advancements in Sequencing Technologies and Low Cost to Drive the Market for Sequencing Applications
           7.4.4 Gene Synthesis
                    7.4.4.1 Increasing Applications of Gene Synthesis and Low Cost to Drive the Market for This Application Segment
           7.4.5 Other Research Applications

8 Oligonucleotide Synthesis Market, By End User (Page No. - 78)
    8.1 Introduction
    8.2 Hospitals
           8.2.1 Hospitals are the Largest End Users of Oligos Due to the Significant Number of Inpatient and Outpatient Visits
    8.3 Academic Research Institutes
           8.3.1 Academic Researchers Primarily Use Oligos for Genetic Engineering, PCR Activities, and High-Throughput Sequencing—A Major Factor Driving Market Growth
    8.4 Pharmaceutical & Biotechnology Companies
           8.4.1 Growing Applications of Oligos in Drug Discovery & Therapeutics to Drive the Demand for Oligonucleotide Synthesis Among These End Users
    8.5 Diagnostic Laboratories
           8.5.1 Diagnostic Laboratories Register High Growth in the Oligonucleotide Synthesis Market Due to the Increasing Significance of Oligos in Molecular Diagnostics

9 Oligonucleotide Synthesis Market, By Region (Page No. - 85)
    9.1 Introduction
    9.2 North America
           9.2.1 US
                    9.2.1.1 Government Initiatives and Strategic Developments By Market Players to Drive Market Growth in the Country
           9.2.2 Canada
                    9.2.2.1 Growing Initiatives and Funding in Synthetic Biology and Genomics to Drive the Market in the Country
    9.3 Europe
           9.3.1 Germany
                    9.3.1.1 Presence of A Large Number of Academic Research Institutes to Support Market Growth
           9.3.2 France
                    9.3.2.1 Government Initiatives to Boost R&D Activities in the Country
           9.3.3 UK
                    9.3.3.1 Growth in the Life Science Industry to Drive the Market for Oligonucleotides Synthesis in the UK
           9.3.4 Italy
                    9.3.4.1 Increasing Research Activities to Drive the Market for Oligonucleotides Synthesis in Italy
           9.3.5 Spain
                    9.3.5.1 Government Initiatives to Drive the Market for Oligonucleotide Synthesis
           9.3.6 RoE
    9.4 Asia Pacific
           9.4.1 China
                    9.4.1.1 Government Initiatives to Strengthen the Biotechnology Industry in China
           9.4.2 Japan
                    9.4.2.1 Increasing Awareness Through Conferences and Workshops to Drive the Market in the Country
           9.4.3 India
                    9.4.3.1 Government Initiatives to Promote Synthetic Biology to Drive the Market in the Country
           9.4.4 RoAPAC
    9.5 Latin America
           9.5.1 Brazil
                    9.5.1.1 Development in Genomics to Aid Market Growth in Brazil
           9.5.2 Mexico
                    9.5.2.1 Increasing Awareness About Advancements in Oligonucleotides to Drive the Market
           9.5.3 RoLAtam
    9.6 Middle East & Africa

10 Competitive Landscape (Page No. - 162)
     10.1 Overview
     10.2 Market Share Analysis
     10.3 Competitive Scenario
             10.3.1 Partnerships, Agreements, Contracts, and Collaborations
             10.3.2 Product Launches, Upgrades, and Approvals
             10.3.3 Expansions
             10.3.4 Acquisitions
     10.4 Competitive Leadership Mapping (2017)
             10.4.1 Vanguards
             10.4.2 Innovators
             10.4.3 Dynamic Players
             10.4.4 Emerging Players
     10.5 Competitive Leadership Mapping for Start-Ups (2018)
             10.5.1 Progressive Companies
             10.5.2 Starting Blocks
             10.5.3 Responsive Companies
             10.5.4 Dynamic Companies
     10.6 MnM Dive-Vendor Comparison Matrix for Start-Ups: Oligonucleotide Synthesis Market

11 Company Profiles (Page No. - 173)
(Business Overview, Products/Services Offered, Recent Developments, and MnM View)*
     11.1 Agilent Technologies
     11.2 Adtbio
     11.3 Bioautomation (Acquired By LGC)
     11.4 Bio-Synthesis Inc.
     11.5 Eurofins Genomics
     11.6 Eurogentec
     11.7 GE Healthcare
     11.8 Genscript
     11.90 Genedesign (Part of Ajinomoto)
     11.1 Integrated DNA Technologies (Acquired By Danaher Corporation)
     11.11 LGC Biosearch Technologies
     11.12 Merck KGaA
     11.13 Nitto Denko Avecia
     11.14 Thermo Fisher Scientific
     11.15 Trilink Biotechnologies (Part of Maravai Lifesciences)

* Business Overview, Products/Services Offered, Recent Developments, and MnM View Might Not Be Captured in Case of Unlisted Companies.

12 Appendix (Page No. - 218)
     12.1 Insights From Industry Experts
     12.2 Discussion Guide
     12.3 Knowledge Store: Marketsandmarkets’ Subscription Portal
     12.4 Available Customizations
     12.5 Related Reports
     12.6 Author Details


List of Tables (157 Tables)

Table 1 Fda-Approved Oligonucleotide-Based Therapies
Table 2 Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 3 Synthesized Oligos Market, By Region, 2017–2024 (USD Million)
Table 4 Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 5 Late-Stage Oligonucleotide-Based Therapies
Table 6 Oligonucleotide-Based Drugs Market, By Region, 2017–2024 (USD Million)
Table 7 Primers Market, By Region, 2017–2024 (USD Million)
Table 8 Probes Market, By Region, 2017–2024 (USD Million)
Table 9 Oligonucleotide Synthesis Market for Intermediate-Scale Synthesized Oligos, By Region, 2017–2024 (USD Million)
Table 10 Large-Scale Synthesized Oligos Market, By Region, 2017–2024 (USD Million)
Table 11 Linkers & Adaptors Market, By Region, 2017–2024 (USD Million)
Table 12 Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 13 Predesigned Oligos Market, By Region, 2017–2024 (USD Million)
Table 14 Custom Oligos Market, By Region, 2017–2024 (USD Million)
Table 15 Oligonucleotide Synthesis Reagents Market, By Region, 2017–2024 (USD Million)
Table 16 Oligonucleotide Synthesis Equipment Market, By Region, 2017–2024 (USD Million)
Table 17 Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 18 Oligonucleotide Synthesis Market for Therapeutic Applications, By Type, 2017–2024 (USD Million)
Table 19 Oligonucleotide Synthesis Market for Therapeutic Applications, By Region, 2017–2024 (USD Million)
Table 20 Antisense Oligonucleotides in Clinical Trials
Table 21 Oligonucleotide Synthesis Market for DNA & Antisense Oligonucleotide-Based Therapies, By Region, 2017–2024 (USD Million)
Table 22 Oligonucleotide Synthesis Market for RNAI Oligonucleotide-Based Therapies, By Region, 2017–2024 (USD Million)
Table 23 Oligonucleotide Synthesis Market for CPG Oligonucleotide-Based Therapies, By Region, 2017–2024 (USD Million)
Table 24 Oligonucleotide Synthesis Market for Diagnostic Applications, By Region, 2017–2024 (USD Million)
Table 25 Oligonucleotide Synthesis Market for Research Applications, By Region, 2017–2024 (USD Million)
Table 26 Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 27 Oligonucleotide Synthesis Market for PCR Applications, By Region, 2017–2024 (USD Million)
Table 28 Oligonucleotide Synthesis Market for QPCR Applications, By Region, 2017–2024 (USD Million)
Table 29 Oligonucleotide Synthesis Market for Sequencing Applications, By Region, 2017–2024 (USD Million)
Table 30 Oligonucleotide Synthesis Market for Gene Synthesis Applications, By Region, 2017–2024 (USD Million)
Table 31 Oligonucleotide Synthesis Market for Other Research Applications, By Region, 2017–2024 (USD Million)
Table 32 Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 33 Oligonucleotide Synthesis Market for Hospitals, By Region, 2017–2024 (USD Million)
Table 34 Oligonucleotide Synthesis Market for Academic Research Institutes, By Region, 2017–2024 (USD Million)
Table 35 Oligonucleotide Synthesis Market for Pharmaceutical & Biotechnology Companies, By Region, 2017–2024 (USD Million)
Table 36 Oligonucleotide Synthesis Market for Diagnostic Laboratories, By Region, 2017–2024 (USD Million)
Table 37 Oligonucleotide Synthesis Market, By Region, 2017–2024 (USD Million)
Table 38 North America: Oligonucleotide Synthesis Market, By Country, 2017–2024 (USD Million)
Table 39 North America: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 40 North America: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 41 North America: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 42 North America: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 43 North America: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 44 North America: Oligonucleotide Synthesis Market for Therapeutic Applications, By Type, 2017–2024 (USD Million)
Table 45 North America: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 46 US: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 47 US: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 48 US: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 49 US: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 50 US: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 51 US: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 52 Canada: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 53 Canada: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 54 Canada: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 55 Canada: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 56 Canada: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 57 Canada: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 58 Europe: Oligonucleotide Synthesis Market, By Country, 2017–2024 (USD Million)
Table 59 Europe: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 60 Europe: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 61 Europe: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 62 Europe: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 63 Europe: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 64 Europe: Oligonucleotide Synthesis Market for Therapeutic Applications, By Type, 2017–2024 (USD Million)
Table 65 Europe: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 66 Germany: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 67 Germany: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 68 Germany: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 69 Germany: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 70 Germany: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 71 Germany: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 72 France: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 73 France: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 74 France: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 75 France: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 76 France: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 77 France: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 78 UK: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 79 UK: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 80 UK: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 81 UK: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 82 UK: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 83 UK: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 84 Italy: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 85 Italy: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 86 Italy: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 87 Italy: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 88 Italy: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 89 Italy: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 90 Spain: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 91 Spain: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 92 Spain: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 93 Spain: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 94 Spain: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 95 Spain: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 96 RoE: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 97 RoE: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 98 RoE: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 99 RoE: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 100 RoE: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 101 RoE: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 102 APAC: Oligonucleotide Synthesis Market, By Country, 2017–2024 (USD Million)
Table 103 APAC: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 104 APAC: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 105 APAC: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 106 APAC: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 107 APAC: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 108 APAC: Oligonucleotide Synthesis Market for Therapeutic Applications, By Type, 2017–2024 (USD Million)
Table 109 APAC: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 110 China: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 111 China: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 112 China: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 113 China: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 114 China: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 115 China: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 116 Japan: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 117 Japan: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 118 Japan: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 119 Japan: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 120 Japan: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 121 Japan: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 122 India: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 123 India: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 124 India: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 125 India: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 126 India: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 127 India: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 128 RoAPAC: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 129 RoAPAC: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 130 RoAPAC: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 131 RoAPAC: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 132 RoAPAC: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 133 RoAPAC: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 134 Latam: Oligonucleotide Synthesis Market, By Country, 2017–2024 (USD Million)
Table 135 Latam: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 136 Latam: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 137 Latam: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 138 Latam: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 139 Latam: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 140 Latam: Oligonucleotide Synthesis Market for Therapeutic Applications, By Type, 2017–2024 (USD Million)
Table 141 Latam: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 142 Brazil: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 143 Brazil: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 144 Brazil: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 145 Mexico: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 146 Mexico: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 147 Mexico: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 148 RoLAtam: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 149 RoLAtam: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 150 RoLAtam: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)
Table 151 MEA: Oligonucleotide Synthesis Market, By Product, 2017–2024 (USD Million)
Table 152 MEA: Synthesized Oligos Market, By Product, 2017–2024 (USD Million)
Table 153 MEA: Synthesized Oligos Market, By Type, 2017–2024 (USD Million)
Table 154 MEA: Oligonucleotide Synthesis Market, By Application, 2017–2024 (USD Million)
Table 155 MEA: Oligonucleotide Synthesis Market for Research Applications, By Type, 2017–2024 (USD Million)
Table 156 MEA: Oligonucleotide Synthesis Market for Therapeutic Applications, By Type, 2017–2024 (USD Million)
Table 157 MEA: Oligonucleotide Synthesis Market, By End User, 2017–2024 (USD Million)


List of Figures (39 Figures)

Figure 1 Research Design
Figure 2 Breakdown of Primary Interviews: By Company Type, Designation, and Region
Figure 3 Data Triangulation Methodology
Figure 4 Synthesized Oligos Dominates the Oligonucleotide Synthesis Market, By Product, 2019—2024 (USD Million)
Figure 5 Oligonucleotide-Based Drugs Segment to Record Highest Growth, 2019–2024 (USD Million)
Figure 6 Predesigned Oligos to Dominate the Oligonucleotide Synthesis Market
Figure 7 Therapeutic Applications Hold the Largest Market Share
Figure 8 Hospitals to Grow at the Highest CAGR in the End-User Market
Figure 9 North America Held Largest Share in 2018 and to Record Highest CAGR (2019–2024)
Figure 10 Increasing Use of Synthesized Oligos in Molecular Diagnostics and Clinical Applications are Driving Market Growth
Figure 11 Oligonucleotide-Based Drugs to Dominate the Market, 2019–2024 (USD Million)
Figure 12 Predesigned Oligos to Command the Largest Share of the Oligonucleotide Synthesis Market During the Forecast Period
Figure 13 PCR Held the Largest Share of the Asia Pacific Research Applications Market in 2019
Figure 14 DNA & Antisense Oligos to Register the Highest Growth Rate During the Forecast Period
Figure 15 Hospitals Segment to Witness Highest CAGR, 2019—2024 (USD Million)
Figure 16 The US to Record the Highest CAGR During the Forecast Period
Figure 17 Oligonucleotide Synthesis Market: Drivers, Restraints, Opportunities, and Challenges
Figure 18 Synthesized Oligos to Record Highest CAGR During the Forecast Period
Figure 19 Therapeutic Applications to Offer Lucrative Growth Opportunities for Market Players During 2019—2024
Figure 20 Hospitals to Dominate the Oligonucleotide Synthesis Market During the Forecast Period
Figure 21 North America: Oligonucleotide Synthesis Market Snapshot
Figure 22 Europe: Oligonucleotide Synthesis Market Snapshot
Figure 23 APAC: Oligonucleotide Synthesis Market Snapshot
Figure 24 Latam: Oligonucleotide Synthesis Market Snapshot
Figure 25 MEA: Oligonucleotide Synthesis Market Snapshot
Figure 26 Key Developments in the Oligonucleotide Synthesis Market (Jan 2016-Jan 2019)
Figure 27 Market Evolution Framework
Figure 28 Global Oligonucleotide Synthesis Market Share Analysis (For Research and Diagnostics), By Key Player, 2017
Figure 29 MnM Dive-Vendor Comparison Matrix: Exosomes Market
Figure 30 Agilent Technologies: Company Snapshot
Figure 31 Eurofins Scientific Group: Company Snapshot
Figure 32 Kaneka: Company Snapshot
Figure 33 General Electric Company (GE): Company Snapshot
Figure 34 Genscript: Company Snapshot
Figure 35 Ajinomoto: Company Snapshot
Figure 36 Danaher Corporation: Company Snapshot
Figure 37 Merck KGaA: Company Snapshot
Figure 38 Nitto Denko Corporation: Company Snapshot
Figure 39 Thermo Fisher Scientific: Company Snapshot

This study involved four major activities to estimate the current size of the oligonucleotide synthesis market. Exhaustive secondary research was carried out to collect information on the market, its peer markets, and its parent market. The next step was to validate these findings, assumptions, and sizing with industry experts across the value chain through primary research. Both top-down and bottom-up approaches were employed to estimate the complete market size. Thereafter, market breakdown and data triangulation procedures were used to estimate the market size of segments and subsegments.

Secondary Research

Secondary research was mainly used to identify and collect information for the extensive, technical, market-oriented, and commercial study of the oligonucleotide synthesis market. The secondary sources used for this study include the International Association Synthetic Biology (IASB), Biotechnology Industry Organization (BIO), Oligonucleotide Therapeutics Society (OTS), American Society of Human Genetics (ASHG), European Society of Human Genetics (ESHG), Indian Institute of Science Education and Research (IISER), National Institutes of Health (NIH), American Chemical Society (ACS), European Diagnostic Manufacturers Association (EDMA), Biotechnology and Biological Sciences Research Council (BBSRC), National Human Genome Research Institute (NHGRI), Genome Canada, Annual Reports, Press Releases, SEC Filings, and Investor Presentations. These sources were also used to obtain key information about major players, market classification, and segmentation according to industry trends, regional/country-level markets, market developments, and technology perspectives.

Primary Research

In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, among other experts, to obtain and verify the critical qualitative and quantitative information as well as assess future prospects of the market. Various primary sources from both the supply and demand sides of the market were interviewed to obtain qualitative and quantitative information. The following is a breakdown of the primary respondents:

Oligonucleotide Synthesis Market

To know about the assumptions considered for the study, download the pdf brochure

Market Size Estimation

Both top-down and bottom-up approaches were used to estimate and validate the total size of the oligonucleotide synthesis market. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:

  • The key players in the industry and market have been identified through extensive secondary research
  • The oligonucleotide synthesis market generated by leading players has been determined through primary and secondary research
  • All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources

Data Triangulation

After arriving at the overall market size from the market size estimation process, the total market was split into several segments and subsegments. To complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments, data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides.

Report Objectives

  • To define, describe, and forecast the global oligonucleotide synthesis market on the basis of product & type, application, end user, and region
  • To provide detailed information about the factors influencing market growth (drivers, restraints, challenges, and opportunities)
  • To strategically analyze micromarkets with respect to individual growth trends, prospects, and contributions to the total market
  • To analyze market opportunities for stakeholders and provide details of the competitive landscape for key players
  • To forecast the size of market segments in North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa
  • To profile key players and comprehensively analyze their product portfolios, market rankings, and core competencies
  • To track and analyze competitive developments, such as acquisitions, product launches, expansions, and agreements in the market

Scope of the report

Report Metric

Details

Market size available for years

2017–2024

Base year considered

2017

Forecast period

2019–2024

Forecast units

Value (USD)

Segments covered

Products & type, applications, end users, and regions

Geographies covered

North America, Europe, the Asia Pacific, Latin America, and the Middle East and Africa

Companies covered

IDT (US), Sigma-Aldrich Corporation (US), Eurogentec (Belgium), Eurofins Genomics (Germany), Agilent Technologies (US), Thermo Fisher Scientific (US) BioAutomation (US), LGC Biosearch Technologies (US), GeneDesign (Japan), GE Healthcare (US), TriLink BioTechnologies (US), GenScript (China), Nitto Denko Avecia (US), ATDBio (UK), Bio-Synthesis (US), IBA GmbH (Germany), Gene Link (US), and AITbiotech Pte. (Singapore)

This report categorizes the oligonucleotide synthesis market into the following segments and subsegments:

Oligonucleotide Synthesis Market, by Product & Type

  • Synthesized Oligonucleotides
    • By Product
      • Oligonucleotide-based Drugs
      • Primers
      • Probes
      • Large-scale Synthesized Oligonucleotides
      • Intermediate-scale Synthesized Oligonucleotides
      • Linkers & Adaptors
    • By Type
      • Custom Oligonucleotides
      • Pre-designed Oligonucleotides
  • Reagents
  • Equipment

Oligonucleotide Synthesis Market, by Application

  • Research
    • PCR
    • QPCR
    • Sequencing
    • Gene Synthesis
    • Other Research Applications (nucleic acid hybridization methods and isothermal amplification methods)
  • Diagnostics
  • Therapeutics 
    • DNA & Antisense Oligonucleotide-based Therapies
    • RNAi Oligonucleotide-based Therapies
    • CpG Oligonucleotide-based Therapies

Oligonucleotide Synthesis Market, by End User

  • Academic & Research Institutes
  • Pharmaceutical & Biotechnology Companies
  • Diagnostic Laboratories
  • Hospitals

Oligonucleotide Synthesis Market, by Region

  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East & Africa

Available Customizations

With the given market data, MarketsandMarkets offers customizations as per the company’s specific needs. The following customization options are available for this report:

Company Information

  • Detailed analysis and profiling of additional market players (up to 5)
Report Code
BT 2680
Published ON
Apr, 2019
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