Organs-on-chips Market

Organs-on-chips Market by Type (Liver, Kidney, Lung, Heart, Intestines, Gut), Offering (Product, Service), Application (Toxicity testing, Physiological model), End User (Academic, Research Institute, Pharma companies) - Global Forecast to 2022

Report Code: BT 5883 Jan, 2018, by marketsandmarkets.com

[117 Pages Report] The organs-on-chips market is expected to reach USD 45.6 Million by 2022 from USD 9.6 Million in 2017, at a CAGR of 36.6%. The growth of this market is mainly driven by the growing focus on developing alternatives for animal testing models, significant increase in research funding and venture capital investments for the development of organs-on-chips, technological advancements and new products launches, growing number of partnerships and collaborations between pharmaceutical companies and organs-on-chips manufacturers, and growing need for early detection of drug toxicity to minimize financial losses due to late stage drug failure.

This report segments the organs-on-chips market into type, offerings, application, end user, and region. Based on type, the organs-on-chips market is segmented into liver, lung, heart, kidney, and other organs-on-chips. In 2017, the accessories segment is expected to account for the largest share of the organs-on-chips market. The large share of this segment can be attributed to the simplicity of this model and the ability of on-chip hepatic tissues to maintain metabolic activity and phenotype similar to the in vivo environment.

Based on application, the organs-on-chips market is segmented into physiological model development, drug discovery, and toxicology research. The drug discovery segment is expected to register the highest CAGR during the forecast period.

Organs-on-chips Market,by Region,2022(USD billion)

In 2017, North America is expected to account for the largest share and also expected to grow at the highest CAGR of the market followed by Europe. The largest share and high growth of this market is attributed to the factors such as the availability of new and advanced organs-on-chips models in the market, favorable government initiatives in terms of funding and programs for basic drug development and research, and the presence of key pharmaceutical companies.

Issues related to the incorporation of organs-on-chips technologies into existing workflows, and complexity of organs-on-chips models may limit market growth to a certain extent in the coming years. The organs-on-chips market is emerging and competitive in nature, with a number of small players competing for market space (including startups firms). Prominent players in this market include Mimetas (Netherlands), Emulate (US), InSphero (Switzerland), Ascendance Bio (US), CN Bio (UK), TissUse (Germany), Kirkstall (UK), HUREL (HUREL) (US), SynVivo (US), AxoSim (US), and Nortis (US).

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Table of Contents

1 Introduction (Page No. - 11)
    1.1 Objectives of the Study
    1.2 Market Definition
    1.3 Market Scope
           1.3.1 Markets Covered
           1.3.2 Years Considered for the Study
    1.4 Currency
    1.5 Limitations
    1.6 Market Stakeholders

2 Research Methodology (Page No. - 14)
    2.1 Research Data
           2.1.1 Secondary Data
                    2.1.1.1 Secondary Sources
           2.1.2 Primary Data
                    2.1.2.1 Primary Sources
                    2.1.2.2 Key Industry Insights
    2.2 Market Size Estimation
    2.3 Market Breakdown and Data Triangulation
    2.4 Assumptions for the Study

3 Executive Summary (Page No. - 22)

4 Premium Insights (Page No. - 26)
    4.1 Organs-on-Chips: Market Overview
    4.2 Europe: Organs-on-Chips: Market, By Application & Country
    4.3 Organs-on-Chips: Market, By Type
    4.4 Organs-on-Chips: Market, By Application

5 Market Overview (Page No. - 29)
    5.1 Introduction
    5.2 Market Dynamics
           5.2.1 Drivers
                    5.2.1.1 Growing Focus on Developing Alternatives for Animal Testing Models
                    5.2.1.2 Significant Increase in Research Funding and Venture Capital Investments for the Development of Organs-on-Chips
                    5.2.1.3 Technological Advancements and New Products Launches
                    5.2.1.4 Growing Number of Partnerships and Collaborations Between Pharmaceutical Companies and Organs-on-Chips Manufacturers
                    5.2.1.5 Growing Need for Early Detection of Drug Toxicity to Minimize Financial Losses Due to Late Stage Drug Failure
                    5.2.1.6 Growing Initiatives to Increase Awareness About Organs-on-Chips Technologies
           5.2.2 Restraint
                    5.2.2.1 Issues Related to the Incorporation of Organs-on-Chips Technologies Into Existing Workflows
           5.2.3 Opportunities
                    5.2.3.1 Increasing Focus on Drug Discovery Activities
                    5.2.3.2 Application of Organs-on-Chips in Oncology Research
                    5.2.3.3 Development of Multiple-Organs-on-A-Chip Models
           5.2.4 Challenges
                    5.2.4.1 Complexity of Organs-on-Chips Models
                    5.2.4.2 Dearth of Skilled Professionals
    5.3 Funding and Venture Capital Investments

6 Organs-on-Chips Market, By Type (Page No. - 38)
    6.1 Introduction
    6.2 Liver
    6.3 Heart
    6.4 Lung
    6.5 Kidney
    6.6 Other Organs

7 Organs-on-Chips Market, By Offering (Page No. - 46)
    7.1 Introduction
    7.2 Products
    7.3 Services

8 Organs-on-Chips Market, By Application (Page No. - 50)
    8.1 Introduction
    8.2 Physiological Model Development
    8.3 Drug Discovery
    8.4 Toxicology Research

9 Organs-on-Chips Market, By End User (Page No. - 58)
    9.1 Introduction
    9.2 Pharmaceutical & Biotechnology Companies
    9.3 Academic & Research Institutes
    9.4 Cosmetics Industry
    9.5 Other End Users

10 Organs-on-Chips Market, By Region (Page No. - 67)
     10.1 Introduction
     10.2 North America
             10.2.1 US
             10.2.2 Canada
     10.3 Europe
             10.3.1 Germany
             10.3.2 UK
             10.3.3 RoE
     10.4 Asia
     10.5 Rest of the World

11 Competitive Landscape (Page No. - 88)
     11.1 Overview
     11.2 Ranking of Players, 2016
     11.3 Competitive Situation and Trends
             11.3.1 Agreements, Partnerships, and Collaborations
             11.3.2 Product Launches
             11.3.3 Expansions

12 Company Profiles (Page No. - 92)
(Overview, Products Offered, Product Offering Scorecard, Business Strategy Scorecard, Recent Developments)*
     12.1 Emulate
     12.2 CN Bio
     12.3 Tissuse
     12.4 Mimetas
     12.5 Insphero
     12.6 Ascendance Bio
     12.7 Kirkstall
     12.8 Hurel
     12.9 Synvivo
     12.10 Axosim
     12.11 Nortis

*Details on Marketsandmarkets View, Overview, Products Offered, Product Offering Scorecard, Business Strategy Scorecard, and Recent Developments Might Not Be Captured in Case of Unlisted Companies.

13 Appendix (Page No. - 109)
     13.1 Insights From Industry Experts
     13.2 Discussion Guide
     13.3 Knowledge Store: Marketsandmarkets’ Subscription Portal
     13.4 Introducing RT: Real-Time Market Intelligence
     13.5 Available Customizations
     13.6 Related Reports
     13.7 Author Details


List of Tables (68 Tables)

Table 1 Key Product Launches/Upgrades
Table 2 Funding & Venture Capital Investments
Table 3 Organs-on-Chips: Market, By Type, 2015–2022 (USD Million)
Table 4 Liver-on-A-Chip Market, By Region, 2015–2022 (USD Thousand)
Table 5 North America: Liver-on-A-Chip Market, By Country, 2015–2022 (USD Thousand)
Table 6 Heart-on-A-Chip Market, By Region, 2015–2022 (USD Thousand)
Table 7 North America: Heart-on-A-Chip Market, By Country, 2015–2022 (USD Thousand)
Table 8 Lung-on-A-Chip Market, By Region, 2015–2022 (USD Thousand)
Table 9 North America: Lung-on-A-Chips Market, By Country, 2015–2022 (USD Thousand)
Table 10 Kidney-on-A-Chip Market, By Region, 2015–2022 (USD Thousand)
Table 11 North America: Kidney-on-A-Chip Market, By Country, 2015–2022 (USD Thousand)
Table 12 Other Organs-on-Chips: Market, By Region, 2015–2022 (USD Thousand)
Table 13 North America: Other Organs-on-Chips: Market, By Country, 2015–2022 (USD Thousand)
Table 14 Organs-on-Chips: Market, By Offering, 2015–2022 (USD Million)
Table 15 North America: Organs-on-Chips Products Market, By Country, 2015–2022 (USD Thousand)
Table 16 North America: Organs-on-Chips Services Market, By Country, 2015–2022 (USD Thousand)
Table 17 Market, By Application, 2015–2022 (USD Million)
Table 18 Market for Physiological Model Development, By Region, 2015–2022 (USD Thousand)
Table 19 North America: Market for Physiological Model Development, By Country, 2015–2022 (USD Thousand)
Table 20 Europe: Market for Physiological Model Development, By Country, 2015–2022 (USD Thousand)
Table 21 Organs-on-Chips: Market for Drug Discovery, By Region, 2015–2022 (USD Thousand)
Table 22 North America: Market for Drug Discovery, By Country, 2015–2022 (USD Thousand)
Table 23 Europe: Market for Drug Discovery, By Country, 2015–2022 (USD Thousand)
Table 24 Market for Toxicology Research, By Region, 2015–2022 (USD Thousand)
Table 25 North America: Market for Toxicology Research, By Country, 2015–2022 (USD Thousand)
Table 26 Europe: Market for Toxicology Research, By Country, 2015–2022 (USD Thousand)
Table 27 Market, By End User, 2015–2022 (USD Million)
Table 28 Market for Pharmaceutical & Biotechnology Companies, By Region, 2015–2022 (USD Thousand)
Table 29 North America: Market for Pharmaceutical & Biotechnology Companies, By Country, 2015–2022 (USD Thousand)
Table 30 Europe: Market for Pharmaceutical & Biotechnology Companies, By Country, 2015–2022 (USD Thousand)
Table 31 Market for Academic & Research Institutes, By Region, 2015–2022 (USD Thousand)
Table 32 North America: Market for Academic & Research Institutes, By Country, 2015–2022 (USD Thousand)
Table 33 Europe: Market for Academic & Research Institutes, By Country, 2015–2022 (USD Thousand)
Table 34 Market for Cosmetics Industry, By Region, 2015–2022 (USD Thousand)
Table 35 North America: Market for Cosmetics Industry, By Country, 2015–2022 (USD Thousand)
Table 36 Europe: Market for Cosmetics Industry, By Country, 2015–2022 (USD Thousand)
Table 37 Market for Other End Users, By Region, 2015–2022 (USD Thousand)
Table 38 North America: Market for Other End Users, By Country, 2015–2022 (USD Thousand)
Table 39 Europe: Market for Other End Users, By Country, 2015–2022 (USD Thousand)
Table 40 Market, By Region, 2015–2022 (USD Million)
Table 41 North America: Market, By Country, 2015–2022 (USD Thousand)
Table 42 North America: Market, By Type, 2015–2022 (USD Thousand)
Table 43 North America: Market, By Offering, 2015–2022 (USD Thousand)
Table 44 North America: Market, By Application, 2015–2022 (USD Thousand)
Table 45 North America: Market, By End User, 2015–2022 (USD Thousand)
Table 46 US: Market, By Offering, 2015–2022 (USD Thousand)
Table 47 US: Market, By Application, 2015–2022 (USD Million)
Table 48 US: Market, By End User, 2015–2022 (USD Thousand)
Table 49 Canada: Market, By Offering, 2015–2022 (USD Thousand)
Table 50 Canada: Market, By Application, 2015–2022 (USD Thousand)
Table 51 Canada: Market, By End User, 2015–2022 (USD Thousand)
Table 52 Europe: Market, By Country, 2015–2022 (USD Thousand)
Table 53 Europe: Market, By Type, 2015–2022 (USD Thousand)
Table 54 Europe: Market, By Offering, 2015–2022 (USD Thousand)
Table 55 Europe: Market, By Application, 2015–2022 (USD Thousand)
Table 56 Europe: Market, By End User, 2015–2022 (USD Thousand)
Table 57 Germany: Market, By Application, 2015–2022 (USD Thousand)
Table 58 Germany: Market, By End User, 2015–2022 (USD Thousand)
Table 59 UK: Market, By Application, 2015–2022 (USD Thousand)
Table 60 UK: Market, By End User, 2015–2022 (USD Thousand)
Table 61 RoE: Market, By Application, 2015–2022 (USD Thousand)
Table 62 RoE: Market, By End User, 2015–2022 (USD Thousand)
Table 63 Asia: Market, By Type, 2015–2022 (USD Thousand)
Table 64 Asia: Market, By Application, 2015–2022 (USD Thousand)
Table 65 Asia: Market, By End User, 2015–2022 (USD Thousand)
Table 66 RoW: Market, By Application, 2015–2022 (USD Thousand)
Table 67 RoW: Market, By End User, 2015–2022 (USD Thousand)
Table 68 Market Ranking Analysis, By Key Player (2016)


List of Figures (27 Figures)

Figure 1 Research Design
Figure 2 Bottom-Up Approach
Figure 3 Top-Down Approach
Figure 4 Break Down of Primary Interviews: By Company, Designation, and Region
Figure 5 Data Triangulation Methodology
Figure 6 Liver-on-A-Chip Market to Grow at the Highest Rate During the Forecast Period
Figure 7 Services Segment to Witness Highest Growth During the Forecast Period
Figure 8 Drug Discovery Segment to Register the Highest Rate During the Forecast Period
Figure 9 Pharmaceutical & Biotechnology Companies to Dominate the Organs-on-Chips End-User Market During the Forecast Period
Figure 10 North America to Witness Highest Growth During the Forecast Period (2017–2022)
Figure 11 Focus on Developing Alternatives to Animal Testing to Drive the Growth of the Market
Figure 12 Toxicology Research to Hold the Largest Share of the Organs-on-Chips Market in Europe(2017)
Figure 13 Liver Segment to Witness High Growth From 2017 to 2022
Figure 14 Toxicology Research Segment to Dominate the Organs-on-Chips Market in 2017
Figure 15 Organs-on-Chips Market: Drivers, Restraints, Opportunities, and Challenges
Figure 16 Number of Registered Clinical Trial Studies (2005–2017)
Figure 17 Liver Segment to Dominate the Organs-on-Chips Market During the Forecast Period
Figure 18 Services Segment to Dominate the Organs-on-Chips Market During the Forecast Period
Figure 19 Toxicology Research is Estimated to Be the Largest Application Segment in the Organs-on-Chips Market
Figure 20 Pharmaceutical & Biotechnology Companies Will Continue to Dominate the Organs-on-Chips Market in 2022
Figure 21 North America Will Continue to Dominate the Organs-on-Chips Market in 2022
Figure 22 North America: Organs-on-Chips Market Snapshot
Figure 23 Europe: Organs-on-Chips Market Snapshot
Figure 24 Asia: Organs-on-Chips Market Snapshot
Figure 25 RoW: Organs-on-Chips Market Snapshot
Figure 26 Strategies Adopted By Market Players (2014–2017)
Figure 27 Market Evolution Framework

The study involved four major activities in estimating the current size of the global organs-on-chips market. Exhaustive secondary research was done to collect information on the market, its peer markets, and its parent market. The next step was to validate these findings, assumptions, and sizing values with industry experts across the value chain through primary research. Both top-down and bottom-up approaches were employed to estimate the complete market size. Thereafter, market breakdown and data triangulation procedures were used to estimate the market size of segments and subsegments.

Secondary Research

Secondary research was mainly used to identify and collect information for the extensive, technical, market-oriented, and commercial study of the global organs-on-chips market. Secondary sources include directories; databases such as Bloomberg Business, Factiva, and Wall Street Journal; white papers; and annual reports were also used to obtain key information about major players, market classification, and segmentation according to industry trends, regional/country-level markets, market developments, and technology perspectives.

Primary Research

In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, among other experts, to obtain and verify the critical qualitative and quantitative information as well as assess prospects of the market. Various primary sources from both the supply and demand sides of the market were interviewed to obtain qualitative and quantitative information. The following is a breakdown of primary respondents:

Organs-on-chips Market:Breakup of Primary Participants

To know about the assumptions considered for the study, download the pdf brochure

Market Size Estimation

Both top-down and bottom-up approaches were used to estimate and validate the total size of the global organs-on-chips. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:

  • The key players in the industry and markets have been identified through extensive secondary research.
      The revenue generated from the sale of organs-on-chips and services by leading players has been determined through primary and secondary research.
  • All percentage shares, splits, and breakdowns have been determined using secondary sources and verified through primary sources.

Data Triangulation

After arriving at the overall market size from the market size estimation process, the total market was split into several segments and subsegments. To complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments, data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides.

Research Objectives

  • To define, describe, segment, and forecast the global organs-on-chips market by product, type, application, and end user
  • To provide detailed information regarding the major factors influencing the growth of the market (drivers, restraints, opportunities, and industry-specific challenges)
  • To strategically analyze micromarkets with respect to individual growth trends, prospects, and contributions to the overall market
  • To analyze the opportunities in the market for stakeholders and provide details of the competitive landscape for the market leaders
  • To forecast the size of the market with respect to four regions, namely, North America, Europe, Asia, and the Rest of the World (RoW)
  • To profile the key players and comprehensively analyze their product portfolios, market positions, and core competencies
  • To track and analyze competitive developments such as acquisitions, agreements, and collaborations, product launch, and , expansions in the organs-on-chips market

Scope of the report

Report Metric

Details

Market size available for years

2015–2022

Base year considered

2016

Forecast period

2017–2022

Forecast units

Value (USD)

Segments covered

Type, Offering, Application, End Users and Region

Geographies covered

North America (US and Canada), Europe (Germany, UK, and RoE), Asia, and the Rest of the World

Companies covered

CN Bio (UK), Emulate (US), TissUse (Germany), Mimetas (Netherlands), InSphero (Switzerland), Ascendance Bio (US), Kirkstall (UK), HUREL (US), SynVivo (US), AxoSim (US), and Nortis (US)

This report categorizes the organs-on-chips market into following segments and subsegments:

By Type

  • Liver-on-a-chip
  • Kidney-on-a-chip
  • Lung-on-a-chip
  • Heart-on-a-chip
  • Other Organs

By Offerings

  • Products
  • Services

By Application

  • Physiological Model Development
  • Drug Discovery
  • Toxicology Research

By End User

  • Pharmaceutical & Biotechnology Companies
  • Academic & Research Institutes
  • Cosmetics Industry
  • Other End Users

By Region

  • North America
    • US
    • Canada
  • Europe
    • Germany
    • UK
    • RoE
  • Asia
  • Rest of the World (RoW)

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The following customization options are available for this report.

Company Information

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Report Code
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Published ON
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