3D Cell Culture Market by Product (Scaffold-free (Hanging Drop, Bioreactor), Microfluidics, Magnetic Levitation), Application (Cancer, Stem Cell Research, Drug Discovery), End User (Pharmaceutical, Biotech, Research) - Global Forecast to 2022
[140 Pages Report] The 3D cell culture market is expected to reach USD 1,720.3 Million by 2022 from USD 570.4 Million in 2016 growing at a CAGR of 20.3% during the forecast period. The base year considered for the study is 2016 and the forecast period is from 2017 to 2022.
Market Dynamics
Focus on developing alternatives to animal testing
Animal models are widely used in cell biology research for studying human-specific diseases. However, this carries several disadvantages—the possibility of harm to animals, difficulties in ensuring result accuracy due to differences in species, disease mechanisms, and drug responses. To overcome these issues, various institutes are involved in developing alternative methods for drug development. The Directive on the Protection of Animals Used for Scientific Purposes (2010/63); the Regulation on Cosmetic Products (1223/2009); REACH (2007/2006); and Classification, Labeling, and Packaging (CLP) (1272/2008) are some European regulations that strongly encourage the replacement of animal testing. Additionally, the Canadian Centre for Alternatives to Animal Methods and Canadian Centre for the Validation of Alternative Methods; Cruelty Free International; and the Fund for the Replacement of Animals in Medical Experiments oppose the use of animal-based models for research.
As 3D cell cultures can serve as an economical alternative to animal models, the current focus on lessening animal use in research is expected to support the growth of the 3D cell culture market.
Lack of infrastructure
The lack of infrastructure for 3D cell-based research is significantly limiting the overall growth of the 3D cell culture market. Basic research laboratories and the necessary equipment to use advanced techniques are some of the prerequisites of cell culture research. 3D cell culture itself is not well supported with required instrumentation and accessories to analyze the cells, although this basic infrastructure is well developed for 2D cell culture. Moreover, many cell culture laboratories still use 2D cell culture, which is very time-consuming, labor-intensive, and error-prone.
Regenerative medicine, an alternative to organ transplantation
Traditional organ transplantation is often risky, due to the possibility of organ rejection; also, the supply of viable organs globally is currently insufficient, with the list of patients requiring organs growing by the day. According to the US Department of Health and Human Services, there were 123,304 people in the US waiting for organ transplants in 2015. The US government estimates that about 30 people die each day, due to the unavailability of organs for transplants.
In this scenario, regenerative medicine—a branch of translational research that involves the regeneration of human cells, tissues, and organs—is gaining increasing importance. 3D cell culture can be employed to create a 3D cellular environment that mimics the physiological conditions of major organ systems; innovative techniques, such as 3D bioprinting and microfluidics can also be used for tissue and organ generation. The focus on regenerative medicine—and 3D cell culture in this application—is expected to grow significantly in the future, which will showcase strong growth opportunities for stakeholders in this sector.
The objectives of this study are as follows:
- To define, describe, segment, and forecast the global market on the basis of product application, end user, and region
- To provide detailed information regarding the major factors influencing the growth of the market (drivers, restraints, opportunities, challenges, and market-specific trends)
- To analyze micromarkets with respect to individual growth trends, future prospects, and contributions to the overall market
- To analyze the opportunities in the market for stakeholders and provide details of competitive landscape for market leaders
- To forecast the size of the market segments with respect to four main regions, namely, North America, Europe, Asia Pacific, and the Rest of the World (RoW)
- To profile key players and comprehensively analyze their market shares and core competencies
- To track and analyze competitive developments such as agreements, partnerships, and collaborations; acquisitions; product launches and approvals; expansions; and R&D activities in the global market
Research Methodology
The study estimates the 3D cell culture market size for 2017 and projects its demand till 2022. In the primary research process, various sources from both demand side and supply side were interviewed to obtain qualitative and quantitative information for the report. Primary sources from the demand side include various industry CEOs, vice presidents, marketing directors, technology and innovation directors, and related key executives from the various players in the global market. For the market estimation process, both top-down and bottom-up approaches were used to estimate and validate the market size of the market as well as to estimate the market size of various other dependent submarkets. All possible parameters that affect the market covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data. This data was consolidated and added to detailed inputs and analysis from MarketsandMarkets and presented in this report.
The 3D cell culture market is highly competitive with the presence of various players. Some of the major players operating in the market are Thermo Fisher (US), Corning (US), Lonza (Switzerland), Merck (Germany), ReproCELL (Japan), and InSphero (Switzerland). The other players operating in this market include Global Cell Solutions (US), Synthecon (US), 3D Biotek (US), Kuraray (Japan), Hamilton Company (US), Mimetas (Netherlands), Emulate (US), Nano3D Biosciences (US), and QGel (Switzerland).
Target Audience for this Report:
- Manufacturers of 3D cell culture products
- Pharmaceutical and biotechnology companies
- Research and development companies
- Research institutes
- Research and consulting firms
- Venture capitalists
Scope of the Report
This report categorizes the market into following segments and subsegments:
By Product
- Scaffold-based 3D Cell Culture
- Hydrogels/ECM Analogs
- Solid Scaffolds
- Micropatterned Surfaces
- Scaffold-free Cell Culture
- Low-adhesion Microplates
- Hanging Drop Plates
- 3D Bioreactors
- 3D Petri Dishes
- Microfluidics-based 3D Cell Culture
- Magnetic levitation & 3D Bioprinting
By Application
- Cancer and Stem Cell Research
- Drug Discovery and Toxicology
- Tissue Engineering & Regenerative Medicine
By End User
- Pharmaceutical & Biotechnology Companies
- Research Institutes
By Region
- North America
- US
- Canada
- Europe
- Germany
- UK
- France
- RoE
- Asia Pacific
- Rest of the World (RoW)
Available Customizations
With the given market data, MarketsandMarkets offers customizations as per the company‘s specific needs.
The following customization options are available for this report.
Company Information
Detailed analysis and profiling of additional market players (up to 5)
The global 3D cell culture market is projected to reach USD 1,720.3 Million by 2022 from USD 682.8 Million in 2017, at a CAGR of 20.3%. Factors such as rising focus on developing alternative methods for animal testing, funding initiatives from government and private investors, technological advancements and product launches, and growing awareness are driving the growth of the market.
The report segments the global market into by type of product, application, end user, and region.
Based on product, the market is segmented into scaffold-based 3D cell culture, scaffold-free 3D cell culture, microfluidics-based 3D cell culture, and magnetic levitation and 3D bioprinting. The scaffold-based 3D cell culture products segment is expected to account for the largest market share in 2017, and is projected to register the highest CAGR during the forecast period. The high growth in this segment is attributed to the ability of scaffold-based products to mimic in vivo conditions, thus driving their adoption among end users.
By type, the scaffold-based 3D cell culture market is segmented into hydrogels/ECM analogs, solid scaffolds, and micropatterned surfaces. The hydrogels/ECM segment analogs are expected to account for the largest share of the scaffold-based market owing to their wide acceptance among researchers.
The global market, by applications, is segmented into cancer and stem cell research, drug discovery and toxicology testing, and tissue engineering & regenerative medicine. The cancer and stem cell research segment is estimated to account for the largest market share in 2017. Growth of this application segment is attributed to increasing incidence of cancer and significant funding initiatives for cancer research from government as well as private organizations.
Based on end users, the market is segmented into pharmaceutical & biotechnology companies and research institutes. In 2017, pharmaceutical and biotechnology companies are expected to form the largest end-user segment. The presence of a large number of pharmaceutical and biotechnology companies, increasing R&D spending in these companies, and growing focus on alternative testing models instead of animal techniques are the key drivers for this end-user segment.
The market is dominated by North America, followed by Europe, Asia Pacific, and the Rest of the World (RoW). The dominance of the North American market is attributed to factors such as increase in incidence of cancer, presence of well-established pharmaceutical and biotechnology industry, and availability of technologically advanced products.
While the Laboratory Informatics market represents significant growth opportunities, market growth may be hindered due to lack of infrastructure for 3D cell culture research. The market is highly competitive with the presence of several big and small players.
To speak to our analyst for a discussion on the above findings, click Speak to Analyst
Table of Contents
1 Introduction (Page No. - 14)
1.1 Objectives of the Study
1.2 Market Definition
1.3 Market Scope
1.3.1 Markets Covered
1.3.2 Years Considered for the Study
1.4 Currency
1.5 Limitations
1.6 Market Stakeholders
2 Research Methodology (Page No. - 17)
2.1 Research Data
2.2 Secondary Data
2.2.1 Secondary Sources
2.3 Primary Data
2.3.1 Primary Sources
2.3.2 Industry Insights
2.4 Market Size Estimation
2.5 Market Breakdown and Data Triangulation
2.6 Market Share Estimation
2.7 Assumptions for the Study
3 Executive Summary (Page No. - 25)
4 Premium Insights (Page No. - 29)
4.1 3D Cell Culture Market Overview
4.2 Global Market, By Product
4.3 Europe: Scaffold-Free Market, By Type
4.4 Global Market, By Application
4.5 Global Market, By End User
4.6 Global Market: Geographic Snapshot
5 Market Overview (Page No. - 33)
5.1 Introduction
5.2 Market Dynamics
5.2.1 Market Drivers
5.2.1.1 Focus on Developing Alternatives to Animal Testing
5.2.1.2 Availability of Funding for Research
5.2.1.3 Technological Advancements & New Product Launches
5.2.1.4 Growing Awareness
5.2.2 Restraints
5.2.2.1 Lack of Infrastructure
5.2.3 Opportunities
5.2.3.1 Emergence of Microfluidics-Based 3D Cell Culture
5.2.3.2 Regenerative Medicine, an Alternative to Organ Transplantation
5.2.4 Challenges
5.2.4.1 Lack of Consistency in 3D Cell Culture Products
6 3D Cell Culture Market, By Product (Page No. - 38)
6.1 Introduction
6.2 Scaffold-Based 3D Cell Culture
6.2.1 Hydrogels/ECM Analogs
6.2.2 Solid Scaffolds
6.2.3 Micropatterned Surfaces
6.3 Scaffold-Free 3D Cell Culture
6.3.1 Low-Adhesion Microplates
6.3.2 Hanging Drop Plates
6.3.3 3D Bioreactors
6.3.4 3D Petri Dishes
6.4 Microfluidics-Based 3D Cell Culture
6.5 Magnetic Levitation & 3D Bioprinting
7 3D Cell Culture Market, By Application (Page No. - 57)
7.1 Introduction
7.2 Cancer and Stem Cell Research
7.3 Drug Discovery and Toxicology Testing
7.4 Tissue Engineering and Regenerative Medicine
8 3D Cell Culture Market, By End User (Page No. - 64)
8.1 Introduction
8.2 Pharmaceutical & Biotechnology Companies
8.3 Research Institutes
9 3D Cell Culture Market, By Region (Page No. - 69)
9.1 Introduction
9.2 North America
9.2.1 US
9.2.2 Canada
9.3 Europe
9.3.1 Germany
9.3.2 UK
9.3.3 France
9.3.4 Rest of Europe (RoE)
9.4 Asia Pacific (APAC)
9.5 Rest of the World (RoW)
10 Competitive Landscape (Page No. - 99)
10.1 Overview
10.2 Market Share Analysis
10.3 Competitive Situation and Trends
10.3.1 Agreements, Partnerships, and Collaborations
10.3.2 Product Launches and Approvals
10.3.3 Expansions
10.3.4 Acquisitions
11 Company Profiles (Page No. - 106)
(Business Overview, Strength of Product Portfolio, Business Strategy Excellence, Recent Developments,)*
11.1 Thermo Fisher Scientific
11.2 Corning
11.3 Merck
11.4 Lonza
11.5 Reprocell
11.6 3D Biotek
11.7 Emulate
11.8 Global Cell Solutions
11.9 Hamilton
11.10 Insphero
11.11 Kuraray
11.12 Mimetas
11.13 Nano3D Biosciences
11.14 Synthecon
11.15 Qgel
*Details on Business Overview, Strength of Product Portfolio, Business Strategy Excellence, Recent Developments, Might Not Be Captured in Case of Unlisted Companies.
12 Appendix (Page No. - 133)
12.1 Insights Form Industry Experts
12.2 Discussion Guide
12.3 Knowledge Store: Marketsandmarkets’ Subscription Portal
12.4 Introducing RT: Real-Time Market Intelligence
12.5 Available Customizations
12.6 Related Reports
12.7 Author Details
List of Tables (111 Tables)
Table 1 Key Product Launches (2014-2017)
Table 2 Recent Conferences, Workshops, and Forums for 3D Cell Culture Market
Table 3 Market, By Product, 2015-2022, USD Million
Table 4 Scaffold-Based Market, By Type, 2015-2022, USD Million
Table 5 Scaffold-Based Market, By Region, 2015-2022, USD Million
Table 6 North America: Scaffold-Based Market, By Country, 2015-2022 (USD Million)
Table 7 Europe: Scaffold-Based Market, By Country, 2015-2022 (USD Million)
Table 8 Hydrogels/ECM Analogs Market, By Region, 2015-2020, USD Million
Table 9 North America: Hydrogels/ECM Analogs Market, By Country, 2015-2022 (USD Million)
Table 10 Europe: Hydrogels/ECM Analogs Market, By Country, 2015-2022 (USD Million)
Table 11 Solid Scaffolds Market, By Region, 2015-2020, USD Million
Table 12 North America: Solid Scaffolds Market, By Country, 2015-2022 (USD Million)
Table 13 Europe: Solid Scaffolds Market, By Country, 2015-2022 (USD Million)
Table 14 Micropatterned Surfaces Market, By Region, 2015-2020, USD Million
Table 15 North America: Micropatterned Surfaces Market, By Country, 2015-2022 (USD Million)
Table 16 Europe: Micropatterned Surfaces Market, By Country, 2015-2022 (USD Million)
Table 17 Scaffold-Free 3D Cell Culture Market, By Type, 2015-2020, USD Million
Table 18 Low-Adhesion Microplates Market, By Region, 2015-2020, USD Million
Table 19 North America: Low-Adhesion Microplates Market, By Country, 2015-2022 (USD Million)
Table 20 Europe: Low-Adhesion Microplates Market, By Country, 2015-2022 (USD Million)
Table 21 Hanging Drop Plates Market, By Region, 2015-2020, USD Million
Table 22 North America: Hanging Drop Plates Market, By Country, 2015-2022 (USD Million)
Table 23 Europe: Hanging Drop Plates Market, By Country, 2015-2022 (USD Million)
Table 24 3D Bioreactors Market, By Region, 2015-2020, USD Million
Table 25 North America: 3D Bioreactors Market, By Country, 2015-2022 (USD Million)
Table 26 Europe: 3D Bioreactors Market, By Country, 2015-2022 (USD Million)
Table 27 3D Petri Dishes Market, By Region, 2015-2020, USD Million
Table 28 North America: 3D Petri Dishes Market, By Country, 2015-2022 (USD Million)
Table 29 Europe: 3D Petri Dishes Market, By Country, 2015-2022 (USD Million)
Table 30 Microfluidics-Based 3D Cell Culture Market, By Region, 2015-2020, USD Million
Table 31 North America: Microfluidics-Based Market, By Country, 2015-2022 (USD Million)
Table 32 Europe: Microfluidics-Based 3D Cell Culture Market, By Country, 2015-2022 (USD Million)
Table 33 Magnetic Levitation & 3D Bioprinting Market, By Region, 2015-2020, USD Million
Table 34 North America: Magnetic Levitation & 3D Bioprinting Market, By Country, 2015-2022 (USD Million)
Table 35 Europe: Magnetic Levitation & 3D Bioprinting Market, By Country, 2015-2022 (USD Million)
Table 36 3D Cell Culture Market, By Application, 2015–2022 (USD Million)
Table 37 Global Market for Cancer and Stem Cell Research, By Region, 2015–2022 (USD Million)
Table 38 North America: Market for Cancer and Stem Cell Research, By Country, 2015–2022 (USD Million)
Table 39 Europe: Market for Cancer and Stem Cell Research, By Country, 2015–2022 (USD Million)
Table 40 3D Cell Culture Market for Drug Discovery and Toxicity Testing, By Region, 2015–2022 (USD Million)
Table 41 North America: Market for Drug Discovery and Toxicity Testing, By Country, 2015–2022 (USD Million)
Table 42 Europe: Market for Drug Discovery and Toxicity Testing, By Country, 2015–2022 (USD Million)
Table 43 Market for Tissue Engineering and Regenerative Medicine, By Region, 2015–2022 (USD Million)
Table 44 North America: Market for Tissue Engineering and Regenerative Medicine, By Country, 2015–2022 (USD Million)
Table 45 Europe: Market for Tissue Engineering and Regenerative Medicine, By Country, 2015–2022 (USD Million)
Table 46 3D Cell Culture Market, By End User, 2015–2022 (USD Million)
Table 47 Market for Pharmaceutical & Biotechnology Companies, By Region, 2015–2022 (USD Million)
Table 48 North America: Market for Pharmaceutical & Biotechnology Companies, By Country, 2015–2022 (USD Million)
Table 49 Europe: Market for Pharmaceutical & Biotechnology Companies, By Country, 2015–2022 (USD Million)
Table 50 Market for Research Institutes, By Region, 2015–2022 (USD Million)
Table 51 North America: Market for Research Institutes, By Country, 2015–2022 (USD Million)
Table 52 Europe: Market for Research Institutes, By Country, 2015–2022 (USD Million)
Table 53 Market, By Region, 2015–2022 (USD Million)
Table 54 North America: 3D Cell Culture Market, By Country, 2015–2022 (USD Million)
Table 55 North America: Market, By Product, 2015–2022 (USD Million)
Table 56 North America: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 57 North America: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 58 North America: Market, By Application, 2015–2022 (USD Million)
Table 59 North America: Market, By End User, 2015–2022 (USD Million)
Table 60 US: 3D Cell Culture Market, By Product, 2015–2022 (USD Million)
Table 61 US: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 62 US: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 63 US: Market, By Application, 2015–2022 (USD Million)
Table 64 US: Market, By End User, 2015–2022 (USD Million)
Table 65 Canada: Market, By Product, 2015–2022 (USD Million)
Table 66 Canada: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 67 Canada: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 68 Canada: Market, By Application, 2015–2022 (USD Million)
Table 69 Canada: Market, By End User, 2015–2022 (USD Million)
Table 70 Europe: 3D Cell Culture Market, By Country, 2015–2022 (USD Million)
Table 71 Europe: Market, By Product, 2015–2022 (USD Million)
Table 72 Europe: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 73 Europe: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 74 Europe: Market, By Application, 2015–2022 (USD Million)
Table 75 Europe: Market, By End User, 2015–2022 (USD Million)
Table 76 Germany: 3D Cell Culture Market, By Product, 2015–2022 (USD Million)
Table 77 Germany: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 78 Germany: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 79 Germany: Market, By Application, 2015–2022 (USD Million)
Table 80 Germany: Market, By End User, 2015–2022 (USD Million)
Table 81 UK: 3D Cell Culture Market, By Product, 2015–2022 (USD Million)
Table 82 UK: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 83 UK: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 84 UK: Market, By Application, 2015–2022 (USD Million)
Table 85 UK: Market, By End User, 2015–2022 (USD Million)
Table 86 France: 3D Cell Culture Market, By Product, 2015–2022 (USD Million)
Table 87 France: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 88 France: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 89 France: Market, By Application, 2015–2022 (USD Million)
Table 90 France: Market, By End User, 2015–2022 (USD Million)
Table 91 RoE: Market, By Product, 2015–2022 (USD Million)
Table 92 RoE: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 93 RoE: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 94 RoE: Market, By Application, 2015–2022 (USD Million)
Table 95 RoE: Market, By End User, 2015–2022 (USD Million)
Table 96 APAC: 3D Cell Culture Market, By Product, 2015–2022 (USD Million)
Table 97 APAC: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 98 APAC: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 99 APAC: Market, By Application, 2015–2022 (USD Million)
Table 100 APAC: Market, By End User, 2015–2022 (USD Million)
Table 101 RoW: 3D Cell Culture Market, By Product, 2015–2022 (USD Million)
Table 102 RoW: Scaffold-Based Market, By Type, 2015–2022 (USD Million)
Table 103 RoW: Scaffold-Free Market, By Type, 2015–2022 (USD Million)
Table 104 RoW : Market, By Application, 2015–2022 (USD Million)
Table 105 RoW: Market, By End User, 2015–2022 (USD Million)
Table 106 Recent Agreements, Partnerships, and Collaborations
Table 107 Recent Product Launch and Approvals
Table 108 Recent Expansions
Table 109 Recent Acquisitions
Table 110 Exchange Rates (Utilized for Conversion of Euro to USD)
Table 111 Exchange Rates (Utilized for Conversion of Chf to USD)
List of Figures (35 Figures)
Figure 1 Research Design
Figure 2 Break Down of Primary Interviews: By Company, Designation, and Region
Figure 3 Market Estimation: Bottom-Up Approach
Figure 4 Global Market Size of 3D Cel Culture Market : Top-Down Approach
Figure 5 Data Triangulation Methododlogy
Figure 6 Scaffold-Based 3D Cell Culture Products to Offer Significant Growth Opportunities
Figure 7 Hydrogels/ECM Analogs to Witness Highest Growth During the Forecast Period
Figure 8 Cancer & Stem Cell Research Segment to Dominate the 3D Cell Culture Applications Market in 2017
Figure 9 Pharmaceutical & Biotechnology Companies to Dominate the 3D Cell Culture End-User Market
Figure 10 Europe to Witness High Growth During the Forecast Period
Figure 11 Focus on Developing Alternatives to Animal Testing to Drive the Growth of the Market
Figure 12 Scaffold-Based 3D Cell Culture to Account for the Largest Market Share in 2017
Figure 13 Europe: Ultra-Low Adhesion Plates to Account for the Largest Share of the Scaffold-Free 3D Cell Culture Market in 2017
Figure 14 Cancer & Stem Cell Research to Witness High Growth From 2017 to 2022
Figure 15 Pharmaceutical & Biotechnology Companies to Account for the Largest Share of the Market in 2017
Figure 16 Germany to Witness Highest Growth During the Forecast Period
Figure 17 Market Drivers, Restraints, Opportunities, and Challenges
Figure 18 Scaffold-Based 3D Cell Culture to Dominate the Market During the Forecast Period
Figure 19 Hydrogels/ECM Analogs to Dominate the Market During the Forecast Period
Figure 20 Low-Adhesion Microplates to Grow at the Highest CAGR During the Forecast Period
Figure 21 Cancer and Stem Cell Research is Estimated to Be the Largest Application Segment in the Market
Figure 22 Pharmaceutical & Biotechnology Companies to Dominate the 3D Cell
Figure 23 Culture Market During the Forecast Period
Figure 24 North America Will Continue to Dominate the Market in 2022
Figure 25 North America: Market Snapshot
Figure 26 Europe: Market Snapshot
Figure 27 Asia Pacific: Market Snapshot
Figure 28 RoW: Market Snapshot
Figure 29 Market Evolution Framework
Figure 30 Market Share Analysis, By Key Player (2016)
Figure 31 Thermo Fisher Scientific, : Company Snapshot (2016)
Figure 32 Corning: Company Snapshot (2016)
Figure 33 Merck : Company Snapshot (2016)
Figure 34 Lonza: Company Snapshot (2016)
Figure 35 Kuraray: Company Overview (2016)
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Growth opportunities and latent adjacency in 3D Cell Culture Market