The US Minimal Residual Disease Market was valued at $371.8 Million in 2024 and projected to reach to $660.7 Million by 2029, representing a compound annual growth rate of 12.2%. The US Minimal Residual Disease market is poised for sustained expansion through 2029, driven by increasing clinical adoption of MRD testing in hematologic malignancies and solid tumors.
| Market Size in | USD 26.32 MN |
| Market Forecast in | |
| CAGR | |
| Forecast Period | |
| Units Considered | Value (USD MN) |
The US MRD market is valued at $371.8 million in 2024, with strong momentum driven by increasing adoption of precision oncology diagnostics across major US healthcare institutions and cancer centers.
With a CAGR of 12.2%, the US market is projected to reach $660.7 million by 2029, reflecting accelerating demand for early cancer detection and treatment monitoring technologies in American healthcare systems.
The US benefits from FDA approvals of advanced MRD testing platforms, strong intellectual property protections, and substantial R&D investments from leading diagnostic and pharmaceutical companies operating in the American market.
High healthcare spending, widespread insurance coverage, and established clinical laboratory networks across the US enable rapid adoption of MRD technologies in oncology practices and hospital systems nationwide.
| Report Metric | Details |
|---|---|
| Base Year | 2024 |
| Fastest Growing Segment | MULTIPLE MYELOMA (Application) |
| Forecast Period | 2024-2029 |
| Growth Rate | CAGR of 12.2% from 2024 to 2029 |
| Largest Segment | ASSAY KITS & REAGENTS (Product) |
| Market Size Base Year (Billions) | ~USD 1.43 (2024) |
| Revenue Forecast (Billions) | ~USD 2.55 (2029) |
| Segments Covered | Product, Technology, Application, Type, End User |
5 segment dimensions are covered across the global market.
| Segment | 2022 | 2023 | 2024 | 2025 | 2026 | 2027 | 2028 | 2029 | CAGR (%) |
|---|---|---|---|---|---|---|---|---|---|
| ACADEMIC & RESEARCH INSTITUTES | 44.6 | 50.4 | 56.7 | 63.7 | 71.3 | 79.5 | 88.5 | 98.2 | 11.6 |
| DIAGNOSTIC LABORATORIES | 138.7 | 159.9 | 183.5 | 210.1 | 239.9 | 273.1 | 310 | 351.1 | 13.9 |
| HOSPITALS & SPECIALTY CLINICS | 227.7 | 259.3 | 293.8 | 332.2 | 374.5 | 420.9 | 471.4 | 527.1 | 12.4 |
| OTHER END USERS | 25.8 | 29.1 | 32.6 | 36.4 | 40.6 | 45.1 | 50 | 55.3 | 11.1 |
| TOTAL | 436.8 | 498.7 | 566.6 | 642.4 | 726.3 | 818.6 | 919.9 | 1031.7 | 12.7 |
The US MRD market was valued at $371.8 million in 2024 and is expected to grow to $660.7 million by 2029.
The US MRD market is projected to grow at a compound annual growth rate (CAGR) of 12.2% from 2024 to 2029.
Growth in the US is driven by rising cancer incidence, increased clinical adoption of MRD testing, strong regulatory support, and growing evidence of MRD's prognostic value in treatment optimization.
Both hematologic malignancies and solid tumors are driving MRD testing adoption in the US, with increasing integration into standard treatment protocols.
The US represents a significant portion of the global MRD market, benefiting from advanced healthcare infrastructure, high spending capacity, and early adoption of precision oncology technologies.
This study involved four major activities in estimating the current size of the minimal residual disease testing market. Exhaustive secondary research was carried out to collect information on the market, its peer markets, and its parent market. The next step was to validate these findings, assumptions, and sizing with industry experts across the value chain through primary research. Both top-down and bottom-up approaches were employed to estimate the complete market size. After that, market breakdown and data triangulation procedures were used to estimate segments and subsegments' market size.
In the secondary research process, various secondary sources such as annual reports, press releases & investor presentations of companies, white papers, certified publications, articles by recognized authors, gold-standard & silver-standard websites, regulatory bodies, and databases (such as D&B Hoovers, Bloomberg Business, and Factiva) were referred to identify and collect information for this study.
In the primary research process, various sources from both the supply and demand sides were interviewed to obtain qualitative and quantitative information for this report. Primary sources were mainly industry experts from the core and related industries and preferred suppliers, manufacturers, distributors, service providers, technology developers, researchers, and organizations related to all segments of this industry’s value chain. In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts, C-level executives of key market players, and industry consultants, to obtain and verify the critical qualitative and quantitative information as well as assess prospects.
The following is a breakdown of the primary respondents:
Note 1: Others include sales managers, marketing managers, and product managers.
Note 2: Companies are classified into tiers based on their total revenues. As of 2022/2023, Tier 1 = >USD 100 million, Tier 2 = USD 10 million to USD 100 million, and Tier 3 = < USD 10 million.
To know about the assumptions considered for the study, download the pdf brochure
| COMPANY NAME | DESIGNATION |
|---|---|
| Roche Ltd. | General Manager |
| Gaurdant | Area Sales Manager |
Both top-down and bottom-up approaches were used to estimate and validate the minimal residual disease testing market's total size. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:
The research methodology used to estimate the market size includes the following:

After arriving at the overall market size applying the process mentioned above, the total market was split into several segments and subsegments. To complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments, data triangulation and market breakdown procedures were employed, wherever applicable. The data was triangulated by studying various factors and trends from both the demand and supply sides.
Minimal Residual Disease (MRD) refers to the small number of cancer cells left in a body after cancer treatment. MRD tests are performed to diagnose and monitor patients with various hematology cancers, such as leukemia, lymphoma, and myeloma. An MRD test looks for cancer cells not killed by chemotherapy or other cancer treatments. Moreover, these tests also play a crucial role in clinical trials of hemato-oncology therapeutics.
Full forecast, segment splits, and company analysis for all Minimal Residual Disease Market.
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