Europe Nucleic Acid Isolation and Purification Market Size, Growth, Share & Trends Analysis
Europe Nucleic Acid Isolation and Purification Market by Product (Kits, Reagents, Instruments), Method (Column, Magnetic Beads), Type (Genomic DNA, Plasmid DNA, mRNA), Application (Diagnostics, Personalized Medicine), End User (CROs) - Forecast to 2030
OVERVIEW
Source: Secondary Research, Interviews with Experts, MarketsandMarkets Analysis
TThe Europe nucleic acid isolation and purification market, valued at USD1.52 billion in 2024, stood at UUSD1.61 billion in 2025 and is projected to advance at a resilient CAGR of 8.4% from 2025 to 2030, culminating in a forecasted valuation of USD2.41 billion by the end of the period. The growth of the Europe nucleic acid isolation and purification market is strongly linked to the region’s high volume of molecular tests and the steady adoption of PCR- and NGS-based workflows. Hospitals, public health labs, and reference laboratories need clean, inhibitor-free DNA/RNA for routine diagnostics, oncology panels, and sequencing. Demand is also rising in infectious disease surveillance, genetic screening, and liquid biopsy/cfDNA testing, where extraction quality directly impacts sensitivity.
KEY TAKEAWAYS
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By CountryGermany accounted for a 33.9% revenue share of the Europe nucleic acid isolation and purification market in 2024.
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By ProductBy product, the kits segment is projected to register the highest growth rate of 8.8% in the Europe nucleic acid isolation and purification market during the forecast period.
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By TypeBy type, the plasmid DNA isolation and purification segment is projected to register a CAGR of 10.0% during the forecast period.
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By methodBy method, the magnetic bead-based isolation and purification segment dominated the market in 2024.
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By ApplicationBy application, the personalized medicine segment is projected to grow at the fastest rate from 2025 to 2030.
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Competitive Landscape - Key PlayersCompanies such as Thermo Fisher Scientific, Merck KGaA, and QIAGEN were identified as some of the key players in the Europe nucleic acid isolation and purification market, given their strong market share and product footprint.
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Competitive Landscape - Startups/SMEsCompanies such as PCR Biosystems and LGC Biosearch Technologies, among others, have distinguished themselves among startups and SMEs by securing strong footholds in specialized niche areas, underscoring their potential as emerging market leaders.
The Europe nucleic acid isolation and purification market is growing with the steady rise in PCR- and NGS-based testing across both clinical and research laboratories. There is an increasing need for high-purity, consistent DNA/RNA to support oncology panels, infectious disease testing, genetic screening, and microbiome research. In Europe, liquid biopsy and cfDNA workflows are also growing and these sample types demand stringent extraction performance to protect sensitivity and reduce variability.
TRENDS & DISRUPTIONS IMPACTING CUSTOMERS' CUSTOMERS
The impact on stakeholders’ businesses in the Europe nucleic acid isolation and purification market is shaped by the region’s shift toward molecular decision-making in healthcare and life sciences. As PCR, qPCR, and NGS become routine across infectious disease testing, oncology profiling, and genetic screening, the demand is rising for high-quality, inhibitor-free DNA/RNA extraction as a critical first step. Across Europe, clinical laboratories, reference labs, and public health networks are major end users because they manage large sample volumes and require speed, consistency, and traceability.
Source: Secondary Research, Interviews with Experts, MarketsandMarkets Analysis
MARKET DYNAMICS
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Growing demand for genetic testing and personalized medicine

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Technological advancements and automation
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High cost of advanced purification systems
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Expansion of point-of-care and rapid diagnostics
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Sample variability and technical hurdles
Source: Secondary Research, Interviews with Experts, MarketsandMarkets Analysis
Driver: Growing demand for genetic testing and personalized medicine
There has been a substantial rise in the demand for nucleic acid isolation and purification kits due to the focus on genetic screening and personalized medicine in the Europe market. As there is an emphasis on personalized medicine based on genetic information, the demand for extracting DNA and RNA in laboratories to perform these analyses has increased, thereby promoting the adoption of advanced nucleic acid purification kits and instruments.
Restraint: High cost of advanced purification systems
Advanced nucleic acid isolation instruments and kits mostly are high priced, which can limit adoption among smaller labs and academic institutions with limited budgets. The cost factor is a significant restraint, especially for advanced automated systems that provide high throughput and precision but require high capital investment.
Opportunity: Expansion of point-of-care and rapid diagnostics
There is an emerging need for more portable and rapid solutions for the isolation of nucleic acids that could be implemented at the point of care, in a clinic setting, or in a decentralized environment. Such rapid purification tools would enable more rapid decision-making for diagnosis, particularly with infectious diseases.
Challenge: Sample variability and technical hurdles
Different biological sample types (e.g., blood, tissues, saliva) present challenges due to diverse nucleic acid concentrations and inhibitory substances. Ensuring consistent recovery and purity across such varied matrices remains a technical challenge in the market, often requiring specialized protocols or reagents. Thus, sample variability is a practical challenge.
EUROPE NUCLEIC ACID ISOLATION AND PURIFICATION MARKET: COMMERCIAL USE CASES ACROSS INDUSTRIES
| COMPANY | USE CASE DESCRIPTION | BENEFITS |
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PHE Cambridge assessed an automated workflow using QIAsymphony RGQ along with artus CMV QS-RGQ assay for CMV DNA testing. | The workflow was positioned as highly suited for CMV DNA extraction and detection in urine and respiratory samples |
Logos and trademarks shown above are the property of their respective owners. Their use here is for informational and illustrative purposes only.
MARKET ECOSYSTEM
The Europe nucleic acid isolation and purification market ecosystem comprises various constituents along the entire sample-to-result process. These include suppliers of extraction kits and reagents such as lysis buffers, silica columns, magnetic beads, and elution/wash chemistry. Apart from these participants, suppliers of automated instruments for extraction, which range from semi-automated to fully automated, user-friendly instruments for efficient extraction, can also be considered part of the Europe landscape. Additionally, Europe has participants in sample collection and stabilization tools like swabs, viral transport media, blood collection tubes for cfDNA, and RNA stabilization solutions.
Logos and trademarks shown above are the property of their respective owners. Their use here is for informational and illustrative purposes only.
MARKET SEGMENTS
Source: Secondary Research, Interviews with Experts, MarketsandMarkets Analysis
Europe Nucleic Acid Isolation and Purification Market, by Product
In 2024, kits dominated the Europe nucleic acid isolation and purification market. This can be attributed to the consumables-intensive nature of nucleic acid extraction, which involves the use of DNA/RNA extraction kits in the process. Clinical and reference labs in the Europe market favor the use of kits due to their validity, standardization, and ease of operation by different operators.
Europe Nucleic Acid Isolation and Purification Market, by Type
In 2024, plasmid DNA isolation and purification dominated the Europe market. This is largely because plasmids are a core part of modern molecular biology workflows. European biopharma and biotech end users use plasmids heavily for gene and cell therapy development, viral vector programs, and mRNA/DNA platform work, where plasmid preparation is a requirement.
Europe Nucleic Acid Isolation and Purification Market, by Method
In 2024, magnetic bead-based isolation and purification accounted for the largest method segment in the Europe market. This is mainly because bead-based workflows are well-suited for automation and high-throughput processing, which many Europe clinical and reference labs rely on. The method delivers strong performance across a wide range of samples, including swabs, blood, plasma, and tissue lysates, while helping reduce inhibitor carryover in PCR- and NGS-linked testing.
Europe Nucleic Acid Isolation and Purification Market, by Application
In 2024, diagnostics was the dominant application in the Europe nucleic acid isolation and purification market. This is mainly because hospital labs, reference laboratories, and public health networks in Europe run large volumes of PCR and qPCR tests that depend on the extraction of clean DNA/RNA. Routine diagnostics in infectious diseases is still driving steady demand, and labs also need reliable extraction for respiratory panels, STI testing, sepsis workups, and blood-borne pathogen screening.
Europe Nucleic Acid Isolation and Purification Market, by End User
In 2024, hospitals and diagnostic centers dominated the Europe nucleic acid isolation and purification market by end user. This is mainly because they run the highest volume of routine PCR/qPCR diagnostics and increasingly support NGS-linked clinical testing. Large hospital networks and regional diagnostic hubs routinely process diverse sample types, so they need extraction workflows that are fast, standardized and repeatable across shifts and sites.
REGION
Germany to be the fastest-growing country in the Europe nucleic acid isolation and purification market during the forecast period
Germany is emerging as the fastest-growing country in the Europe nucleic acid isolation and purification market. This is supported by its strong diagnostics footprint and well-established life sciences ecosystem. The country has a dense network of hospital laboratories, reference labs, and research institutes, due to which it has a high demand for routine DNA/RNA extraction across the PCR and sequencing workflow.

EUROPE NUCLEIC ACID ISOLATION AND PURIFICATION MARKET: COMPANY EVALUATION MATRIX
In the Europe nucleic acid isolation and purification market matrix, Thermo Fisher Scientific (star) is a key player with strong reach across hospital labs, reference labs, academic institutes, and biopharma teams. Its portfolio covers magnetic bead- and column-based extraction kits, automation-ready workflows, and supporting plastics and buffers. LGC Biosearch Technologies (Emerging Leader) is enhancing its market position in Europe for enabling high-performance nucleic acid analysis.
Source: Secondary Research, Interviews with Experts, MarketsandMarkets Analysis
KEY MARKET PLAYERS
- Thermo Fisher Scientific, Inc. (US)
- Danaher Corporation (US)
- QIAGEN (Germany)
- F. Hoffman-La Roche (Switzerland)
- Agilent Technologies, Inc. (US)
- Illumina, Inc. (US)
- Merck KGaA (Germany)
- Bio-Rad Laboratories Inc. (US)
- LGC Biosearch Technologies (UK)
MARKET SCOPE
| REPORT METRIC | DETAILS |
|---|---|
| Market Size in 2024 (Value) | USD 1.52 Billion |
| Market Forecast in 2030 (Value) | USD 2.41 Billion |
| Growth Rate | CAGR of 8.4% from 2025-2030 |
| Years Considered | 2023-2030 |
| Base Year | 2024 |
| Forecast Period | 2025-2030 |
| Units Considered | Value (USD Billion) |
| Report Coverage | Revenue Forecast, Company Ranking, Competitive Landscape, Growth Factors, and Trends |
| Segments Covered |
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| Countries Covered | Germany, UK, France, Italy, Spain, and Rest of Europe |
| Parent & Related Segment Reports |
Nucleic Acid Isolation & Purification Market North America Nucleic Acid Isolation and Purification Market Asia Pacific Nucleic Acid Isolation and Purification Market Nucleic Acid Isolation and Purification Kits Market |
WHAT IS IN IT FOR YOU: EUROPE NUCLEIC ACID ISOLATION AND PURIFICATION MARKET REPORT CONTENT GUIDE

DELIVERED CUSTOMIZATIONS
We have successfully delivered the following deep-dive customizations:
| CLIENT REQUEST | CUSTOMIZATION DELIVERED | VALUE ADDS |
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| Europe diagnostics company planning to scale molecular testing |
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RECENT DEVELOPMENTS
- September 2023 : QIAGEN launched two new nucleic acid extraction kits: the QIAwave RNeasy Plus Mini Kit and QIAwave DNA/RNA Mini Kit, eco-friendlier versions of the RNeasy Plus Mini Kit and the All DNA/RNA Mini Kit.
- August 2023 : Danaher entered into a definitive agreement to acquire all the outstanding shares of Abcam. Through this development, Abcam is expected to operate as a standalone operating company within Danaher's Life Sciences segment.
- January 2023 : QIAGEN launched the EZ2 Connect MDx platform for automated sample processing in diagnostic labs.
Table of Contents
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Methodology
This research study involved the extensive use of secondary sources, directories, and databases to identify and collect valuable information for the analysis of the nucleic acid isolation and purification kit market. In-depth interviews were conducted with various primary respondents, including key industry participants, subject-matter experts (SMEs), C-level executives of key market players, and industry consultants, to obtain and verify critical qualitative and quantitative information and assess the growth prospects of the market. The global market size estimated through secondary research was then triangulated with inputs from primary research to arrive at the final market size.
Secondary Research
The secondary sources referred for this research study include publications from government sources such as the World Health Organization (WHO), National Institutes of Health (NIH), Centers for Disease Control and Prevention (CDC), European Society of Human Genetics (ESHG), University Hospitals Southampton NHS Foundation Trust, Genomics England, Scottish Genome Partnership, Berlin Institute of Health, Max Delbrück Center for Molecular Medicine, and European Federation of Biotechnology (EFB). Company Websites, Annual Reports, SEC Filings, Press Releases, Investor Presentations, Journals, Expert Interviews, and MarketsandMarkets Analysis. Secondary data was collected and analyzed to arrive at the overall size of the global market, which was then validated by primary research.
Primary Research
Primary research was conducted to validate the market segmentation, identify key players, and gather insights into key industry trends and market dynamics.
Extensive primary research was conducted after acquiring basic knowledge about the global market scenario through secondary research. Several primary interviews were conducted with market experts from the demand side (hospitals and diagnostics centers, academic institutes and government organizations, pharmaceutical and biotechnology companies, and others) and supply side (C-level and D-level executives, product managers, and marketing and sales managers of key manufacturers, distributors, and channel partners, among others, from Tier 1 and Tier 2 companies engaged in offering products) across five major regions, namely, North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa. Approximately 80% of primary interviews were conducted with supply-side representatives, while demand-side participants accounted for the remaining share. The primary data was collected through questionnaires, e-mails, online surveys, personal interviews, and telephonic interviews.
Market Size Estimation
The report presents a detailed assessment of the nucleic acid isolation and purification kit market and qualitative inputs and insights from MarketsandMarkets. The total market size was determined after data triangulation from three different approaches. After completing each approach, the weighted average of the three approaches was taken based on each approach’s level of assumptions. A detailed market estimation approach was followed to estimate and validate the value of the market and other dependent submarkets. These methods were also used extensively to estimate the size of various subsegments in the market. The research methodology used to estimate the market size includes the following:
- From the list of manufacturers in the market, companies were identified and finalized from secondary research.
- Revenues for individual companies were gathered from public sources and databases.
- The business shares of leading players were gathered from secondary sources to the extent available. In certain cases, the shares of product businesses were ascertained through a detailed analysis of various parameters, including product portfolios and market positioning.
- Individual shares or revenue estimates were validated through expert interviews.
Approach: MnM Repository Analysis
For the estimation of the nucleic acid isolation and purification kit market, related market reports in the MnM repository were considered. The global and regional market values of the nucleic acid isolation and purification kit and dependent submarkets were extracted from the MnM repository and validated through secondary and primary research. The final global market size was triangulated through the average of all approaches and validated through primary interviews with industry experts.
Data Triangulation
After arriving at the market size from the market size estimation process explained above, the total market was divided into several segments and subsegments. Data triangulation and market breakdown procedures were employed, wherever applicable, to complete the overall market engineering process and arrive at the exact statistics for all segments and subsegments.
Market Definition:
nucleic acid isolation and purification kit is a set of molecular biology techniques used for the extraction of DNA and RNA for use in downstream applications, such as sequencing, cloning, and polymerase chain reaction. These downstream applications are important parts of life science research, molecular diagnostics, forensics, and genetic engineering.
Key Stakeholders
- Manufacturers and vendors of nucleic acid isolation and purification kit kits and instruments
- Research associations related to genomics
- Hospitals & diagnostic centers
- Contract research organizations
- Healthcare institutions
- Research institutes
- Pharmaceutical & biotechnology companies
- Government & academic institutes
- Community centers
Report Objectives
- To define, describe, and forecast the nucleic acid isolation and purification kit market by product, method, type, application, end user, and region
- To provide detailed information regarding the major factors influencing the market growth (such as drivers, restraints, opportunities, and challenges)
- To strategically analyze micro markets with respect to individual growth trends, future prospects, and contributions to the overall market
- To analyze the opportunities in the market for stakeholders and provide details of the competitive landscape for market leaders
- To forecast the size of the market segments with respect to five main regions: North America, Europe, the Asia Pacific, Latin America, and the Middle East & Africa
- To profile the key players and comprehensively analyze their product portfolios, market positions, and core competencies
- To track and analyze competitive developments, such as acquisitions, product launches, expansions, agreements, partnerships, and collaborations, in the global market
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